Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Barnaby Balmforth"'
Autor:
Paulina Klaudyna Powalowska, Barnaby Balmforth, Palmer Rebecca, Ana-Luisa Silva, Eleanor R. Gray, Magdalena Stolarek, Cameron Alexander Frayling, Bram Herman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Accurate detection of somatic variants, against a background of wild-type molecules, is essential for clinical decision making in oncology. Existing approaches, such as allele-specific real-time PCR, are typically limited to a single target gene and
Autor:
Eleanor Gray, Justyna Mordaka, Efthimia Christoforou, Kristine von Bargen, Nicola Potts, Rebecca Palmer, Barnaby Balmforth
Publikováno v:
Cancer Research. 82:4104-4104
Introduction: The FDA has approved 11 therapies for non-small cell lung cancer (NSCLC) patients diagnosed with gene fusions. Importantly, these life-saving targeted therapies remain underutilized due to a lack of cost-effective, comprehensive, and si
Autor:
Paulina Powalowska, Nicola Potts, Brandon A. Smith, Kala F. Schilter, Honey V. Reddi, Lan Beppu, Jerald Radich, Charles Massie, Quentin Vicentini, Tom Brown, Robert Osborne, Barnaby Balmforth
Publikováno v:
Cancer Research. 82:4105-4105
Introduction: While the FDA has approved over 20 targeted therapies for non-small cell lung cancer (NSCLC), less than half of patients in the US undergo comprehensive biomarker testing to determine if they would benefit from these agents. This gap in
Autor:
David M. Love, James Bush, Fabian Tolle, Lindsey A Ibbotson, Boris Breiner, Neil M. Bell, Aya Shibahara, Ana-Luisa Silva, Olympia Pachoumi, Kerr Johnson, Cameron Alexander Frayling, Magdalena Stolarek, Michele Amasio, Leigh R Shelford, Podd Gareth, Mei Wu, Maciej Sosna, Barnaby Balmforth, Aurel Negrea, Douglas J Kelly, Sheridan Eoin, Edoardo Petrini, Tom H Isaac, Jasmin Chana, Paul H. Dear, Monica S Saavedra, Palmer Rebecca, Alexander Dunning, Mark Dethlefsen, Jekaterina Kuleshova
Publikováno v:
Nucleic Acids Research
A new approach to single-molecule DNA sequencing in which dNTPs, released by pyrophosphorolysis from the strand to be sequenced, are captured in microdroplets and read directly could have substantial advantages over current sequence-by-synthesis meth
Autor:
Douglas J Kelly, David M. Love, Barnaby Balmforth, Tim J Puchtler, Ana-Luisa Silva, Rachel Knox, Magdalena Stolarek, James Bush, Aya Shibahara, Richard J Ingham, Cameron Alexander Frayling, Jekaterina Kuleshova, Palmer Rebecca, Alexander Dunning, Lindsey A Ibbotson, Paulina Klaudyna Powalowska, Emma L Talbot, Justyna M Mordaka, Tom H Isaac, Podd Gareth, Maciej Sosna, Aurel Negrea, Paul H. Dear, Kerr Johnson, Mei Wu, Michael Haggis-Powell, Ibrahim S Topkaya, Thomas Huckvale, Boris Breiner, Andreas M Waeber, Evangelia-Nefeli Athanasopoulou, Oliver J Newell, Cunha Pedro, Jasmin Chana, Justinas Šlikas, Neil M. Bell, Christina Xyrafaki, Mark Dethlefsen
Publikováno v:
Nucleic Acids Research
Despite remarkable progress in DNA sequencing technologies there remains a trade-off between short-read platforms, having limited ability to sequence homopolymers, repeated motifs or long-range structural variation, and long-read platforms, which ten