The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo

Autor: Brook, Byron, Checkervarty, Abhinav Kumar, Barman, Soumik, Sweitzer, Cali, Bosco, Anna-Nicole, Sherman, Amy C., Baden, Lindsey R., Morrocchi, Elena, Sanchez-Schmitz, Guzman, Palma, Paolo, Nanishi, Etsuro, O’Meara, Timothy R., McGrath, Marisa E., Frieman, Matthew B., Soni, Dheeraj, van Haren, Simon D., Ozonoff, Al, Diray-Arce, Joann, Steen, Hanno, Dowling, David J., Levy, Ofer

Publikováno v: In iScience 15 November 2024 27(11)

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance

Autor: O'Meara, Timothy R., Nanishi, Etsuro, McGrath, Marisa E., Barman, Soumik, Dong, Danica, Dillen, Carly, Menon, Manisha, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Ernst, Robert K., Levy, Ofer, Frieman, Matthew B., Dowling, David J.

Publikováno v: In The Journal of Allergy and Clinical Immunology November 2023 152(5):1107-1120

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Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination.

Autor: Dowling, David J.^1,2 (AUTHOR), Barman, Soumik^1,2 (AUTHOR), Smith, Alyson J.^3,4 (AUTHOR), Borriello, Francesco^1,2,5,6,7 (AUTHOR), Chaney, Danielle^1,2 (AUTHOR), Brightman, Spencer E.¹ (AUTHOR), Melhem, Gandolina¹ (AUTHOR), Brook, Byron^1,2 (AUTHOR), Menon, Manisha¹ (AUTHOR), Soni, Dheeraj^1,2 (AUTHOR), Schüller, Simone^1,2 (AUTHOR), Siram, Karthik⁸ (AUTHOR), Nanishi, Etsuro^1,2 (AUTHOR), Bazin, Hélène G.^3,8 (AUTHOR), Burkhart, David J.^3,8 (AUTHOR), Levy, Ofer^1,2,9 (AUTHOR) ofer.levy@childrens.harvard.edu, Evans, Jay T.^3,8 (AUTHOR) jay.evans@mso.umt.edu

Publikováno v: Scientific Reports. 10/18/2022, Vol. 12 Issue 1, p1-17. 17p.

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