Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science.

Autor: Breault É; Institut de Pharmacologie de Sherbrooke, Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12e avenue Nord, Sherbrooke, QC J1H 5N4, Canada., Desgagné M; Institut de Pharmacologie de Sherbrooke, Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12e avenue Nord, Sherbrooke, QC J1H 5N4, Canada., Neve J; Research Group of Organic Chemistry, Departments of Chemistry and Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, Brussels 1050, Belgium., Côté J; Institut de Pharmacologie de Sherbrooke, Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12e avenue Nord, Sherbrooke, QC J1H 5N4, Canada., Barlow TMA; Research Group of Organic Chemistry, Departments of Chemistry and Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, Brussels 1050, Belgium., Ballet S; Research Group of Organic Chemistry, Departments of Chemistry and Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, Brussels 1050, Belgium., Sarret P; Institut de Pharmacologie de Sherbrooke, Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12e avenue Nord, Sherbrooke, QC J1H 5N4, Canada. Electronic address: philippe.sarret@usherbrooke.ca.

Publikováno v: Pharmacological research [Pharmacol Res] 2024 Nov; Vol. 209, pp. 107408. Date of Electronic Publication: 2024 Sep 21.

Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses.

Autor: Lozada C; BioCIS, CNRS, CY Cergy-Paris Université, Cergy-Pontoise, France.; Research Group of Organic Chemistry, Vrije Universiteit Brussel, Brussels, Belgium., Barlow TMA; Research Group of Organic Chemistry, Vrije Universiteit Brussel, Brussels, Belgium., Gonzalez S; BioCIS, CNRS, CY Cergy-Paris Université, Cergy-Pontoise, France., Lubin-Germain N; BioCIS, CNRS, CY Cergy-Paris Université, Cergy-Pontoise, France., Ballet S; Research Group of Organic Chemistry, Vrije Universiteit Brussel, Brussels, Belgium.

Publikováno v: Frontiers in chemistry [Front Chem] 2021 Aug 23; Vol. 9, pp. 689006. Date of Electronic Publication: 2021 Aug 23 (Print Publication: 2021).

Essential role of an ERV-derived Env38 protein in adaptive humoral immunity against an exogenous SVCV infection in a zebrafish model.

Autor: Hong, Yun¹ (AUTHOR), Hu, Chong-bin¹ (AUTHOR), Bai, Jun¹ (AUTHOR), Fan, Dong-dong¹ (AUTHOR), Lin, Ai-fu¹ (AUTHOR), Xiang, Li-xin¹ (AUTHOR) xianglx@zju.edu.cn, Shao, Jian-zhong^1,2 (AUTHOR) xianglx@zju.edu.cn

Publikováno v: PLoS Pathogens. 4/4/2023, Vol. 18 Issue 4, p1-39. 39p.

From antibiotic to antiviral: computational screening reveals a multi-targeting antibiotic from Streptomyces spp. against Nipah virus fusion proteins.

Autor: Odchimar NMO; Virology and Vaccine Research and Development Program, Department of Science and Technology - Industrial Technology Development Institute, 1631, Taguig City, Metro Manila, Philippines., Macalalad MAB; Virology and Vaccine Research and Development Program, Department of Science and Technology - Industrial Technology Development Institute, 1631, Taguig City, Metro Manila, Philippines., Orosco FL; Virology and Vaccine Research and Development Program, Department of Science and Technology - Industrial Technology Development Institute, 1631, Taguig City, Metro Manila, Philippines. orosco.fredmoore@gmail.com.; S&T Fellows Program, Department of Science and Technology, 1631, Taguig City, Metro Manila, Philippines. orosco.fredmoore@gmail.com.; Department of Biology, College of Arts and Sciences, University of the Philippines - Manila, 1000, Manila, Metro Manila, Philippines. orosco.fredmoore@gmail.com.

Publikováno v: Molecular diversity [Mol Divers] 2024 Jul 26. Date of Electronic Publication: 2024 Jul 26.

Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion.

Autor: Lāce, Ilze, Cotroneo, Elena R., Hesselbarth, Nils, Simeth, Nadja A.

Publikováno v: Journal of Peptide Science; May2023, Vol. 29 Issue 5, p1-30, 30p