Výsledky vyhledávání - "Barlow, David John"

Nicotinamide N-methyltransferase in health and disease, with special reference to cancer

Autor: Ramsden, David B., Waring, RH, Barlow, David John, Parsons, Richard Bramwell

Publikováno v: Ramsden, D B, Waring, RH, Barlow, D J & Parsons, R B 2017, ' Nicotinamide N-methyltransferase in health and disease, with special reference to cancer ', International Journal of Tryptophan Research, vol. 10, pp. 1-19 . https://doi.org/10.1177/1178646917691739

Over the past decade, the roles of nicotinamide N-methyltransferase and its product 1-methyl nicotinamide have emerged from playing merely minor roles in phase 2 xenobiotic metabolism as actors in some of the most important scenes of human life. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::a2da4308c6c17db8ae1ace0584881486
https://kclpure.kcl.ac.uk/ws/files/94738197/J_Trypt_Res_NNMT_review_in_health_and_disease_special_reference_to_cancer.pdf

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Application of Machine Learning in Knowledge Discovery for Pharmaceutical Drug-drug Interactions

Autor: Herrero Zazo, Maria, Lille, Maxime, Barlow, David John

Publikováno v: Herrero Zazo, M, Lille, M & Barlow, D J 2016, ' Application of Machine Learning in Knowledge Discovery for Pharmaceutical Drug-drug Interactions ', CEUR Workshop Proceedings . < http://ceur-ws.org/Vol-1748/paper-13.pdf >

Artificial neural networks (ANNs) have been developed to predict the clinical significance of drug-drug interactions (DDIs) for a set of 35 phar-maceutical drugs using data compiled from the Web-based resources, Lexi-comp® and Vidal®, with inputs f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::a27fac3414bf983e01050f6fc9938957
https://kclpure.kcl.ac.uk/en/publications/c668d806-df49-43f3-becf-2c8e189e90f7

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Periodical

Conformational Analysis of 9-Substituted Adenines in Relation to Their Microsomal N1-Oxidation

Autor: Lam, Siu Ping, Barlow, David John, Gorrod, John William

Publikováno v: Journal of Pharmacy and Pharmacology; June 1989, Vol. 41 Issue: 6 p373-378, 6p

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Dissertation/ Thesis

Agonists of the transcriptional Keap1-Nrf2 gatekeeper

Autor: Gacesa, Ranko

Oxidative stress has been associated with numerous degenerative diseases and disorders, as well as cancer and the process of ageing. In higher animals, the response to oxidative stress is largely regulated by the master transcription factor Nrf2, whi

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718628

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Dissertation/ Thesis

Design, synthesis and antimalarial evaluation of novel azafluorenone analogues

Autor: Huang, Xiangchen

With the rapid spread of drug resistance to chloroquine, the development of effective, safe, and affordable antimalrial drugs has become one of the most pressing health priorities worldwide. Two azafluorenone alkaloids isolated from Mitrephora divers

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679789

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Dissertation/ Thesis

The role of nicotinamide N-methyltransferase in Parkinson's disease

Autor: Thomas, Martin Geoffrey

Parkinson’s disease (PD) is a progressive neurological movement disorder characterised by degenerating dopaminergic neurons in the midbrain’s substantia nigra pars compacta (SNpc). In the majority of cases, PD is thought to be caused by a plethor

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677129

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Elektronická kniha

British Biographical Index

Autor: Tommaso Nappo

The British Biographical Index, 3rd cumulated and enlarged ed., contains information on more than 420,000 individuals from Great Britain and Ireland from the beginnings until the end of the 20th century. 760 sources, published between 1601 and 2002,

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