Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Baris E. Polat"'
Autor:
Stacy Mo, Baris E. Polat, Ross Barman, Robert Langer, Sharanya Srinivasan, Daniel Blankschtein, Carl M. Schoellhammer
Publikováno v:
PMC
Low-frequency ultrasound presents an attractive method for transdermal drug delivery. The controlled, yet non-specific nature of enhancement broadens the range of therapeutics that can be delivered, while minimizing necessary reformulation efforts fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d324fd9181b9d81312454ca43c300a7a
https://doi.org/10.1016/j.jconrel.2015.02.002
https://doi.org/10.1016/j.jconrel.2015.02.002
Publikováno v:
Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement ISBN: 9783662532713
In this chapter, the combination of ultrasound and other physical enhancers, such as injections, electroporation, microneedles, and microdermabrasion, as well as the simultaneous use of low-frequency and high-frequency ultrasound, for enhanced transd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::397c3693f5400f1ecebb9731d670263b
https://doi.org/10.1007/978-3-662-53273-7_23
https://doi.org/10.1007/978-3-662-53273-7_23
Publikováno v:
PMC
The synergism between low-frequency sonophoresis (LFS) and chemical penetration enhancers (CPEs), especially surfactants, in transdermal enhancement has been investigated extensively since this phenomenon was first observed over a decade ago. In spit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d256cff03fb4aa98d222445c5ef6629
https://doi.org/10.1016/j.jconrel.2011.11.008
https://doi.org/10.1016/j.jconrel.2011.11.008
Autor:
Daniel Blankschtein, Baris E. Polat, Jonathan D. Mendenhall, Robert Langer, Brett VanVeller, Shangchao Lin
Publikováno v:
The Journal of Physical Chemistry B. 115:1394-1402
Sulforhodamine B (SRB), a common fluorescent dye, is often considered to be a purely hydrophilic molecule, having no impact on bulk or interfacial properties of aqueous solutions. This assumption is due to the high water solubility of SRB relative to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115c5cde03ecc81074bb0584ec75fecc
https://doi.org/10.1021/jp109866q
https://doi.org/10.1021/jp109866q
Autor:
Daniel Blankschtein, Baris E. Polat, Renata Fonseca Vianna Lopez, Jennifer E. Seto, Robert Langer
Publikováno v:
PMC
The simultaneous application of ultrasound and the surfactant sodium lauryl sulfate (referred to as US/SLS) to skin enhances transdermal drug delivery (TDD) in a synergistic mechanical and chemical manner. Since full-thickness skin (FTS) and split-th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fb52bc81888fad1d359885ce343d56
https://doi.org/10.1016/j.jconrel.2010.03.013
https://doi.org/10.1016/j.jconrel.2010.03.013
Autor:
Gregory Y. Lauwers, Ruby Maa, Baris E. Polat, Daniel G. Anderson, Daniel Blankschtein, Avi Schroeder, Carl M. Schoellhammer, Robert Langer, Giovanni Traverso
Publikováno v:
Traverso
Both patients and physicians prefer the oral route of drug delivery. The gastrointestinal (GI) tract, though, limits the bioavailability of certain therapeutics because of its protease and bacteria-rich environment as well as general pH variability f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4d81c349c48afa5eafcfd5274db602
https://pubmed.ncbi.nlm.nih.gov/25250829
https://pubmed.ncbi.nlm.nih.gov/25250829
Publikováno v:
PMC
Importance of the field: Transdermal delivery of macromolecules provides an attractive alternative route of drug administration when compared to oral delivery and hypodermic injection because of its ability to bypass the harsh gastrointestinal tract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff0f4aedb00308fe9033107c0d10390
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0003-4255-0492
Publikováno v:
PMC
This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS). Pig full-thickness skin (FTS) and pig split-thickness skin (STS) treated with LFS/SL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ec7e8e006addb22aa5d479d51c116f
https://europepmc.org/articles/PMC3085549/
https://europepmc.org/articles/PMC3085549/
Publikováno v:
PMC
The use of ultrasound for the delivery of drugs to, or through, the skin is commonly known as sonophoresis or phonophoresis. The use of therapeutic and high frequencies of ultrasound (≥ 0.7 MHz) for sonophoresis (HFS) dates back to as early as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f94a98867e0cd4a09eabcfd2e2abf5
http://hdl.handle.net/1721.1/99225
http://hdl.handle.net/1721.1/99225
Publikováno v:
PMC
Recent advances in transdermal drug delivery utilizing low-frequency sonophoresis (LFS) and sodium lauryl sulfate (SLS) have revealed that skin permeability enhancement is not homogenous across the skin surface. Instead, highly perturbed skin regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22588fbdab60a1e277822b00e3953f89
https://pubmed.ncbi.nlm.nih.gov/20740667
https://pubmed.ncbi.nlm.nih.gov/20740667