Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Baris Alten"'
Autor:
Klaudia Jaczynska, Luis Esquivies, Richard A. Pfuetzner, Baris Alten, Kyle D. Brewer, Qiangjun Zhou, Ege T. Kavalali, Axel T. Brunger, Josep Rizo
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 26-50 (2023)
Characterizing interactions of Synaptotagmin‐1 with the SNARE complex is crucial to understand the mechanism of neurotransmitter release. X‐ray crystallography revealed how the Synaptotagmin‐1 C2B domain binds to the SNARE complex through a so
Externí odkaz:
https://doaj.org/article/4c5a346bf0504f2d810b8e365e02f59e
The nanoscale organization of proteins within synapses is critical for maintaining and regulating synaptic transmission and plasticity. Here, we use cryogenic electron tomography to directly visualize thein situthree-dimensional architecture and supr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::372463d595a62305b1930ec8eee3a073
https://doi.org/10.1101/2023.05.12.540562
https://doi.org/10.1101/2023.05.12.540562
Autor:
Klaudia Jaczynska, Luis Esquivies, Richard A. Pfuetzner, Baris Alten, Kyle D. Brewer, Qiangjun Zhou, Ege T. Kavalali, Axel T. Brunger, Josep Rizo
Publikováno v:
FEBS open bioReferences.
Characterizing interactions of Synaptotagmin-1 with the SNARE complex is crucial to understand the mechanism of neurotransmitter release. X-ray crystallography revealed how the Synaptotagmin-1 C
Autor:
Marwan Shinawi, Malay A. Phoong, Angela E. Scheuerle, Susan M. Voglmaier, Nitin Khandelwal, Magda S. Santos, Elliott H. Sherr, Roxanne Simmons, Ege T. Kavalali, Michael Chez, Ruiji Jiang, Haiyan Li, Bethany Smith-Packard, Kendall C. Parks, Shaun A. Hussain, Audrey Cortesi, Baris Alten, Brianna M. Paul, Sanam J. Lalani, Heather G. Fisher
Publikováno v:
Human Mutation. 41:1999-2011
Clinical and genetic features of five unrelated patients with de novo pathogenic variants in the synaptic vesicle-associated membrane protein 2 (VAMP2) reveal common features of global developmental delay, autistic tendencies, behavioral disturbances
Publikováno v:
Biophysical Journal. 122:419a
Publikováno v:
Cell reports
SUMMARY Inhibition of neurotransmitter release by neurotransmitter substances constitutes a fundamental means of neuromodulation. In contrast to well-delineated mechanisms that underlie inhibition of evoked release via suppression of voltage-gated Ca
Autor:
Lisa M. Monteggia, Rong Sun, Ok-Ho Shin, Pei-Yi Lin, K Ian White, Baris Alten, Qiangjun Zhou, Axel T. Brunger, Ege T. Kavalali, Luis Esquivies, Wendy K. Chung
Publikováno v:
Neuron. 109(1)
SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) complex, composed of synaptobrevin, syntaxin, and SNAP25, forms the essential fusion machinery for neurotransmitter release. Recent studies have reported several mutations
Publikováno v:
Cell Reports. 38:110255
Autor:
Sadik Taskin Tas, Erva Bayraktar, Yildirim Sara, Baris Alten, Canan Kurşungöz, Metin Yesiltepe, Ayse Yesim Gocmen, Ana Martínez
Publikováno v:
British Journal of Pharmacology. 175:4450-4463
BACKGROUND AND PURPOSE Children and adolescents are the top consumers of high-fructose corn syrup (HFCS) sweetened beverages. Even though the cardiometabolic consequences of HFCS consumption in adolescents are well known, the neuropsychiatric consequ