Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bari Gabbitas"'
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Journal of Bone and Mineral Research. 9:1999-2005
Insulin-like growth factors (IGF) I and II are among the most prevalent growth factors secreted by bone cells and are presumed to act as autocrine regulators of bone formation. Certain growth factors, synthesized by skeletal cells and known to stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5b0e90610b750d4472da4313d8ecfa
https://doi.org/10.1002/jbmr.5650091221
https://doi.org/10.1002/jbmr.5650091221
Insulin-Like Growth Factor II Promoter Expression in Cultured Rodent Osteoblasts and Adult Rat Bone*
Publikováno v:
Endocrinology. 139:2287-2292
Insulin-like growth factor (IGF)-II stimulates bone formation by increasing the replication of cells of the osteoblastic lineage and by enhancing the differentiated function of the osteoblast. Although IGF-II is synthesized by skeletal cells, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c695389c761fc2cf2aab83a5f4bbd34
https://doi.org/10.1210/endo.139.5.5964
https://doi.org/10.1210/endo.139.5.5964
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Journal of Cellular Physiology. 172:253-264
Insulin-like growth factors (IGF) I and II are the most abundant growth factors secreted by skeletal cells, and retinoic acid has many important actions on cell differentiation and osteoblastic function. Some of these actions may be mediated by chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::904e5b4d98cad832cde11274ecb01288
https://doi.org/10.1002/(sici)1097-4652(199708)172:2<253::aid-jcp12>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199708)172:2<253::aid-jcp12>3.0.co
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Journal of Cellular Biochemistry. 66:77-86
Previously we have shown that transforming growth factor β (TGF β) 1, basic fibroblast growth factor (FGF), and platelet-derived growth factor (PDGF) BB inhibit the synthesis of insulin-like growth factor (IGF) II, but their effects on IGF binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f4b3411544cbfb1c0810898e02076a
https://doi.org/10.1002/(sici)1097-4644(19970701)66:1<77::aid-jcb9>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19970701)66:1<77::aid-jcb9>3.0.co
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Journal of Cellular Physiology. 169:15-22
Retinoic acid has important actions on cell differentiation and osteoblastic function, and some of these actions may be mediated by changes in the insulin-like growth factor (IGF) axis. Skeletal cells synthesize IGF I and II and the six known IGF bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f565a4492a6bbabf2fd8b364ad79360f
https://doi.org/10.1002/(sici)1097-4652(199610)169:1<15::aid-jcp2>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199610)169:1<15::aid-jcp2>3.0.co
Publikováno v:
Journal of Biological Chemistry. 271:9033-9038
Glucocorticoids inhibit the synthesis of insulin-like growth factor-binding protein-5 (IGFBP-5) in osteoblasts, but the mechanisms involved are unknown. IGFBP-5 stimulates bone cell growth, and its inhibition by glucocorticoids may be relevant to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc059d40ae3fab7330d59246bea2b27
https://doi.org/10.1074/jbc.271.15.9033
https://doi.org/10.1074/jbc.271.15.9033
Publikováno v:
Endocrinology. 137:431-437
Platelet-derived growth factor (PDGF), a bone cell mitogen, stimulates bone collagen degradation and does not enhance bone matrix apposition rates. The mechanism of the effect on collagen degradation is unknown, and it could involve changes in inters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58777bae8184e321ba52524cf7bbee6a
https://doi.org/10.1210/endo.137.2.8593786
https://doi.org/10.1210/endo.137.2.8593786
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
The American journal of physiology. 275(2)
Insulin-like growth factors (IGFs) I and II are considered to be autocrine regulators of bone cell function. Recently, we demonstrated that IGF-I induces IGF-binding protein-5 (IGFBP-5) expression in cultures of osteoblast-enriched cells from 22-day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2959a871884ad8032b6c0648cbed024
https://pubmed.ncbi.nlm.nih.gov/9688622
https://pubmed.ncbi.nlm.nih.gov/9688622
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Endocrinology. 137(5)
Previous work indicate that glucocorticoids inhibit the synthesis of insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IG-FBP-3), -4, and -5, but not IGFBP-6, in osteoblast cultures. IGFBP-6 binds IGF-II with high affinity and prevents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b1d6fc9b82b60ddf8162c7bae2b395
https://pubmed.ncbi.nlm.nih.gov/8612502
https://pubmed.ncbi.nlm.nih.gov/8612502
Autor:
Ernesto Canalis, Bari Gabbitas
Publikováno v:
Endocrinology. 136(6)
Previous work from our laboratory indicated that bone morphogenetic protein-2 (BMP-2) enhances the synthesis of insulin-like growth factor-I (IGF-I) and IGF-II by skeletal cells. The activity of IGF-I and -II is regulated by six known IGF-binding pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38156749b7c385b41c60cd34be36cd7f
https://pubmed.ncbi.nlm.nih.gov/7538461
https://pubmed.ncbi.nlm.nih.gov/7538461