Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors

Autor: Nielsen, C.M., Ogbe, A., Pedroza-Pacheco, I., Doeleman, S.E., Chen, Y., Silk, S.E., Barrett, J.R., Elias, S.C., Miura, K., Diouf, A., Bardelli, M., Dabbs, R.A., Barfod, L., Long, C.A., Haynes, B.F., Payne, R.O., Minassian, A.M., Bradley, T., Draper, S.J., Borrow, P.

Interactions between B cells and CD4+ T follicular helper (Tfh) cells are key determinants of humoral responses. Using samples from clinical trials performed with the malaria vaccine candidate antigen Plasmodium falciparum merozoite protein (PfRH5),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::a73375caba41718468c1e924b56e483c

Functional comparison of blood-stage plasmodium falciparum malaria vaccine candidate antigens

Autor: Illingworth, JJ, Alanine, DG, Brown, R, Marshall, JM, Bartlett, HE, Silk, SE, Labbé, GM, Quinkert, D, Cho, JS, Wendler, JP, Pattinson, DJ, Barfod, L, Douglas, AD, Shea, MW, Wright, KE, De Cassan, SC, Higgins, MK, Draper, SJ

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)

The malaria genome encodes over 5,000 proteins and many of these have also been proposed to be potential vaccine candidates, although few of these have been tested clinically. RH5 is one of the leading blood-stage Plasmodium falciparum malaria vaccin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1dcbdd2a007f51dcba3068477caac2d9
http://ora.ox.ac.uk/objects/uuid:

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

Autor: Payne, RO, Silk, SE, Elias, SC, Miura, K, Diouf, A, Galaway, F, de Graaf, H, Brendish, NJ, Poulton, ID, Griffiths, OJ, Edwards, NJ, Jin, J, Labbé, GM, Alanine, DG, Siani, L, Di Marco, S, Roberts, R, Green, N, Berrie, E, Ishizuka, A.S., Nielsen, C.M., Bardelli, M., Partey, F.D., Ofori, M.F., Barfod, L., Wambua, J., Murungi, L.M., Osier, F.H., Biswas, S., McCarthy, J.S., Minassian, A.M., Ashfield, R., Viebig, N.K., Nugent, F.L., Douglas, A.D., Vekemans, J., Wright, G.J., Faust, S.N., Hill, A.V., Long, C.A., Lawrie, A.M., Draper, S.J.

Publikováno v: Payne, R O, Silk, S E, Elias, S C, Miura, K, Diouf, A, Galaway, F, de Graaf, H, Brendish, N J, Poulton, I D, Griffiths, O J, Edwards, N J, Jin, J, Labbé, G M, Alanine, D G, Siani, L, Di Marco, S, Roberts, R, Green, N, Berrie, E, Ishizuka, A S, Nielsen, C M, Bardelli, M, Partey, F D, Ofori, M F, Barfod, L, Wambua, J, Murungi, L M, Osier, F H, Biswas, S, McCarthy, J S, Minassian, A M, Ashfield, R, Viebig, N K, Nugent, F L, Douglas, A D, Vekemans, J, Wright, G J, Faust, S N, Hill, A V, Long, C A, Lawrie, A M & Draper, S J 2017, ' Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions ', JCI insight, vol. 2, no. 21, e96381 . https://doi.org/10.1172/jci.insight.96381

The development of a highly effective vaccine remains a key strategic goal to aid the control and eventual eradication of Plasmodium falciparum malaria. In recent years, the reticulocyte-binding protein homolog 5 (RH5) has emerged as the most promisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6bf35a8938147f9a47ac6504de737b6a
http://ora.ox.ac.uk/objects/uuid:

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.