Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Barent N. DuBois"'
Autor:
Kripa Shankar, Nathan P. Metzger, Connor Lawrence, Deepali Gupta, Sherri Osborne-Lawrence, Salil Varshney, Omprakash Singh, Corine P. Richard, Alexander N. Zaykov, Rebecca Rolfts, Barent N. DuBois, Diego Perez-Tilve, Bharath K. Mani, Suntrea T.G. Hammer, Jeffrey M. Zigman
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101950- (2024)
Objective: The number of individuals affected by metabolic dysfunction associated fatty liver disease [1] is on the rise, yet hormonal contributors to the condition remain incompletely described and only a single FDA-approved treatment is available.
Externí odkaz:
https://doaj.org/article/d718b66ab372463e861b5c868d549a2d
Publikováno v:
Basicclinical pharmacologytoxicologyREFERENCES.
Chronic intraperitoneal injection of thioacetamide (TAA) in rats has been used as an animal model of human cirrhosis to study the effects of the disease on drug metabolism. However, TAA inhibits P450 enzymes directly and independently of cirrhosis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7163e5c67c6dce8a436b2c894e4a38f2
https://pubmed.ncbi.nlm.nih.gov/36370118
https://pubmed.ncbi.nlm.nih.gov/36370118
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 118:432-439
Adult individuals born with intrauterine growth restriction (IUGR) have physiological maladaptations that significantly increase risk of chronic disease. We suggested that such abnormalities in organ function would alter pharmacokinetics throughout l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9e914a6fa62116234bbe688977d203
https://doi.org/10.1111/bcpt.12523
https://doi.org/10.1111/bcpt.12523
Publikováno v:
Contraception. 91:71-75
Pharmacokinetics of norethindrone in combination oral contraceptive regimen are well described among HIV+ women treated with ritonavir-boosted protease inhibitor therapies; however, such characterization is lacking in women using progestin-only contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433459be48ecc8c300d28cd25e1b94aa
https://doi.org/10.1016/j.contraception.2014.08.009
https://doi.org/10.1016/j.contraception.2014.08.009
Autor:
Ganesh Cherala, Kent L. Thornburg, Barent N. DuBois, Jacob Pearson, Duc X. Nguyen, Tahir Mahmood
Publikováno v:
European Journal of Pharmacology. 728:39-47
Perinatal growth restriction programs higher risk for chronic disease during adulthood via morphological and physiological changes in organ systems. Perinatal growth restriction is highly correlated with a decreased nephron number, altered renal func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdc4f28d79f609d84effd64cde2bd73
https://doi.org/10.1016/j.ejphar.2014.01.056
https://doi.org/10.1016/j.ejphar.2014.01.056
Autor:
Ganesh Cherala, Myrna Y. Munar, Martha McInnis, Alison Edelman, Barent N. DuBois, Jeffrey T. Jensen, Frank Z. Stanczyk
Publikováno v:
Contraception. 87:220-226
Background Pharmacokinetic (PK) parameters based on short sampling times (48 h or less) may contain inaccuracies due to their dependency on extrapolated values. This study was designed to measure PK parameters with greater accuracy in obese users of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383855fdedf67a23316fc39c8a80e59a
https://doi.org/10.1016/j.contraception.2012.10.008
https://doi.org/10.1016/j.contraception.2012.10.008
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 42(3)
Dear Editor, With great enthusiasm we read a report of long-term programming of cytochrome P450 enzyme activities into adulthood as a result of early life insult ([Sohi et al., 2013][1]). It is likely that birth weight, a surrogate for early life env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab81bf48883dd866500477bc1a5f3e82
https://pubmed.ncbi.nlm.nih.gov/24212381
https://pubmed.ncbi.nlm.nih.gov/24212381
Autor:
Ganesh Cherala, Jacob Pearson, Kent L. Thornburg, Jacob E. Friedman, Barent N. DuBois, Perrie F. O'Tierney-Ginn
Cytochrome P4501A1 (CYP1A1), an important drug metabolizing enzyme, is expressed in human placenta throughout gestation as well as in fetal liver. Obesity, a chronic inflammatory condition, is known to alter CYP enzyme expression in non-placental tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9041879b1f2f827ad578e69d290cfa
https://europepmc.org/articles/PMC3504187/
https://europepmc.org/articles/PMC3504187/
Autor:
Tammy Chan, Bonnie Hastings, Ali Alnakhli, Tahir Mahmood, Jacob Pearson, Ganesh Cherala, Barent N. DuBois
Publikováno v:
Nutrition research (New York, N.Y.). 33(3)
Altered perinatal environment, often manifested as low birth weight, is thought to contribute to greater susceptibility for hypertension, hyperlipidemia, and diabetes as a result of epigenetic modifications and alteration of transcriptional activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efeff0761a401b73f6addb41336bc6cf
https://pubmed.ncbi.nlm.nih.gov/23507230
https://pubmed.ncbi.nlm.nih.gov/23507230