Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.

Autor: Lohoff T; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Epigenetics Programme, Babraham Institute, Cambridge, UK., Ghazanfar S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Missarova A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK., Koulena N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Pierson N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Griffiths JA; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Genomics Plc, Cambridge, UK., Bardot ES; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Eng CL; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Tyser RCV; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Argelaguet R; Epigenetics Programme, Babraham Institute, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK., Guibentif C; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Sahlgrenska Center for Cancer Research, Department of Microbiology and Immunology, University of Gothenburg, Gothenburg, Sweden., Srinivas S; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Briscoe J; The Francis Crick Institute, London, UK., Simons BD; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; The Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK., Hadjantonakis AK; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Göttgens B; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Reik W; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. wolf.reik@babraham.ac.uk.; Epigenetics Programme, Babraham Institute, Cambridge, UK. wolf.reik@babraham.ac.uk.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK. wolf.reik@babraham.ac.uk.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. wolf.reik@babraham.ac.uk., Nichols J; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. jn270@cam.ac.uk.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. jn270@cam.ac.uk., Cai L; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. lcai@caltech.edu., Marioni JC; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. marioni@ebi.ac.uk.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK. marioni@ebi.ac.uk.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. marioni@ebi.ac.uk.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2022 Jan; Vol. 40 (1), pp. 74-85. Date of Electronic Publication: 2021 Sep 06.

A Watershed Finding for Heart Regeneration.

Autor: Bardot ES; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dubois NC; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: nicole.dubois@mssm.edu.

Publikováno v: Cell [Cell] 2019 Feb 21; Vol. 176 (5), pp. 947-949.

Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network.

Autor: Perdigoto CN; Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bardot ES; Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Valdes VJ; Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Santoriello FJ; Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ezhkova E; Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA elena.ezhkova@mssm.edu.

Publikováno v: Development (Cambridge, England) [Development] 2014 Dec; Vol. 141 (24), pp. 4690-6.

Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells.

Autor: Bardot ES; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Valdes VJ, Zhang J, Perdigoto CN, Nicolis S, Hearn SA, Silva JM, Ezhkova E

Publikováno v: The EMBO journal [EMBO J] 2013 Jul 17; Vol. 32 (14), pp. 1990-2000. Date of Electronic Publication: 2013 May 14.

Epigenetic regulation of skin: focus on the Polycomb complex.

Autor: Zhang J, Bardot ES, Ezhkova E

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2012 Jul; Vol. 69 (13), pp. 2161-2172.