Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer

Autor: Corda, Gabriele, Sala, Gianluca, Lattanzio, Rossano, Iezzi, Manuela, Sallese, Michele, Fragassi, Giorgia, Lamolinara, Alessia, Mirza, Hasan, Barcaroli, Daniela, Ermler, Sibylle, Silva, Elisabete, Yasaei, Hemad, Newbold, Robert F., Vagnarelli, Paola, Mottolese, Marcella, Natali, Pier Giorgio, Perracchio, Letizia, Quist, Jelmar, Grigoriadis, Anita, Marra, Pierfrancesco, Tutt, Andrew N., Piantelli, Mauro, Iacobelli, Stefano, De Laurenzi, Vincenzo, Sala, Arturo

Publikováno v: The Journal of Pathology
Corda, G, Sala, G, Lattanzio, R, Iezzi, M, Sallese, M, Fragassi, G, Lamolinara, A, Mirza, H, Barcaroli, D, Ermler, S, Silva, E, Yasaei, H, Newbold, R F, Vagnarelli, P, Mottolese, M, Natali, P G, Perracchio, L, Quist, J, Grigoriadis, A, Marra, P, Tutt, A N, Piantelli, M, Iacobelli, S, De Laurenzi, V & Sala, A 2017, ' Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer ', Journal of pathology, vol. 241, no. 3, pp. 350-361 . https://doi.org/10.1002/path.4841

Frizzled receptors mediate Wnt ligand signalling, which is crucially involved in regulating tissue development and differentiation, and is often deregulated in cancer. In this study, we found that the gene encoding the Wnt receptor frizzled 6 (FZD6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e715b94912d8d8df179fb986eee8a8b
https://pubmed.ncbi.nlm.nih.gov/27859262

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Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling

Autor: Oddi, Sergio, Dainese, Enrico, Sandiford, Simone, Fezza, Filomena, Lanuti, Mirko, Chiurchiù, Valerio, Totaro, Antonio, Catanzaro, Giuseppina, Barcaroli, Daniela, De Laurenzi, Vincenzo, Centonze, Diego, Mukhopadhyay, Somnath, Selent, Jana, Howlett, Allyn C., Maccarrone, Mauro

The CB(1) cannabinoid receptor is regulated by its association with membrane microdomains such as lipid rafts. Here, we investigated the role of palmitoylation of the CB(1) receptor by analysing the functional consequences of site-specific mutation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::40761dc0e43c180ccb2be13964efa44f
http://hdl.handle.net/2108/53372

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