Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Barbra Sasu"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/dd13ef1431cc4f949f301e3b91f80ee8
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/59acd264995d4d32b8f77ceda825dac7
Autor:
Kristen Zhang, Jerick Sanchez, Duy Nguyen, Barbra Sasu, Elvin J Lauron, Vidhya Ramanathan, George Nguyen, Cesar Sommer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/5d4b61874df0479a8030ae4c5125f6ec
Autor:
Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Cell-based immunotherapies have had remarkable success in the clinic, specifically in the treatment of hematologic malignancies. However, these strategies have had limited efficacy in patients with solid tumors. To better understand the challenges in
Externí odkaz:
https://doaj.org/article/f4500c9773db47d7abfb74eccac2d857
Autor:
Ana M. Metelo, Agnieszka Jozwik, Le Anh Luong, Delaney Dominey-Foy, Charlotte Graham, Charlotte Attwood, Shafqat Inam, Alan Dunlop, Katy Sanchez, Kirsty Cuthill, Carmel Rice, Matthew Streetly, Trevor Bentley, Bijan Boldajipour, Cesar Sommer, Barbra Sasu, Reuben Benjamin
Publikováno v:
Cancer Research Communications. 2:158-171
Multiple myeloma remains an incurable plasma cell malignancy despite the rapidly evolving treatment landscape. Chimeric antigen receptor T cells targeted against BCMA have recently shown great promise in relapsed refractory multiple myeloma; however,
Autor:
Hsinyuan Cheng, Michael Yi, Michael Bethune, Eric Gschweng, Melinda Au, Duy Nguyen, Kristen Zhang, Tanu Shenoy, Barbra Sasu, Thomas Van Blarcom, Cesar Sommer
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Barbra Sasu
Publikováno v:
Immuno Oncology Insights. 2:187-193
Autor:
Pascua Edward Derrick, Barbra Sasu, Javier Chaparro-Riggers, Regina Lin, Robert T. Abraham, Spencer Park, Zea Melton, Xiaodi Deng, Theodore O. Johnson, Jaume Pons, Kevin Lindquist, Thomas Van Blarcom, Bijan Boldajipour, Christopher R. Kimberlin, Yvonne S. L. Mak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells.
Autor:
Janette Sutton, Cesar Sommer, Hsin-Yuan Cheng, Moustafa Hamze, Javier Chaparro-Riggers, Julianne Smith, Danielle Dettling, Duy Nguyen, Barbra Sasu, Julien Valton, Ivana Djuretic, Yik Andy Yeung
Publikováno v:
Mol Ther
Patients with relapsed or refractory acute myeloid leukemia (AML) have a dismal prognosis and limited treatment options. Chimeric antigen receptor (CAR) T cells have achieved unprecedented clinical responses in patients with B cell leukemias and lymp
Autor:
Siler Panowski, Surabhi Srinivasan, Nguyen Tan, Silvia Tacheva-Grigorova, Bryan Smith, Yvonne Mak, Hongxiu Ning, Jonathan Villanueva, Dinali Wijewarnasuriya, Shanshan Lang, Zea Melton, Adit Ghosh, Mathilde Dusseaux, Roman Galetto, Jonathan Heyen, Tao Sai, Thomas Van Blarcom, Javier Chaparro-Riggers, Barbra Sasu
Publikováno v:
Cancer Research. 82:LB210-LB210
CD70 is highly expressed on renal cell carcinoma (RCC), with limited normal tissue expression, making it an attractive CAR T target for an immunogenic solid tumor indication. Here we generated and characterized a panel of anti-CD70 scFv-based CAR T c