(-)-Tarchonanthuslactone: Design of New Analogues, Evaluation of their Antiproliferative Activity on Cancer Cell Lines, and Preliminary Mechanistic Studies.

Autor: Toneto Novaes LF; Institute of Chemistry, University of Campinas (Unicamp), C.P. 6154, 13084-971, Campinas, SP (Brazil)., Martins Avila C; Institute of Chemistry, University of Campinas (Unicamp), C.P. 6154, 13084-971, Campinas, SP (Brazil)., Pelizzaro-Rocha KJ; Department of Biochemistry, Biology Institute, University of Campinas (Unicamp), 13083-862, Campinas, SP (Brazil)., Vendramini-Costa DB; Division of Pharmacology and Toxicology-CPQBA, University of Campinas (Unicamp), 13083-970, Campinas, SP (Brazil)., Pereira Dias M; Department of Biochemistry, Biology Institute, University of Campinas (Unicamp), 13083-862, Campinas, SP (Brazil)., Barbosa Trivella DB; Brazilian Biosciences National Laboratory, National Center for Research in Energy and Material, 13083-970, Campinas, SP (Brazil)., Ernesto de Carvalho J; Division of Pharmacology and Toxicology-CPQBA, University of Campinas (Unicamp), 13083-970, Campinas, SP (Brazil)., Ferreira-Halder CV; Department of Biochemistry, Biology Institute, University of Campinas (Unicamp), 13083-862, Campinas, SP (Brazil)., Pilli RA; Institute of Chemistry, University of Campinas (Unicamp), C.P. 6154, 13084-971, Campinas, SP (Brazil). pilli@iqm.unicamp.br.

Publikováno v: ChemMedChem [ChemMedChem] 2015 Oct; Vol. 10 (10), pp. 1687-99. Date of Electronic Publication: 2015 Aug 25.