1,2,4-Oxadiazole Derivatives: Physicochemical Properties, Antileishmanial Potential, Docking and Molecular Dynamic Simulations of Leishmania infantum Target Proteins.

Autor: Barbosa DCS; Department of Microbiology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil., Holanda VN; Department of Biomedicine, University Center of Vitória de Santo Antão (UNIVISA), Vitória de Santo Antão 55610-050, PE, Brazil., Lima EMA; Center for Exact and Natural Sciences, Federal University of Pernambuco (UFPE), Recife 50740-560, PE, Brazil., Cavalcante MKA; Parasitology Laboratory, Academic Center of Vitória, Federal University of Pernambuco (UFPE), Recife 50670-420, PE, Brazil.; Department of Immunology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil., Brelaz-de-Castro MCA; Parasitology Laboratory, Academic Center of Vitória, Federal University of Pernambuco (UFPE), Recife 50670-420, PE, Brazil.; Department of Immunology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil., Chaves EJF; Department of Chemistry, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil., Rocha GB; Department of Chemistry, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil., Silva CJO; Department of Fundamental Chemistry, Federal University of Pernambuco (UFPE), Recife 50740-540, PE, Brazil., Oliveira RN; Department of Chemistry, Federal Rural University of Pernambuco (UFRPE), Recife 52171-900, PE, Brazil., Figueiredo RCBQ; Department of Microbiology, Aggeu Magalhães Institute (IAM-FIOCRUZ), Recife 50740-465, PE, Brazil.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2024 Sep 30; Vol. 29 (19). Date of Electronic Publication: 2024 Sep 30.