Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Barbora Vitovcova"'
Autor:
Katerina Dvorakova, Veronika Skarkova, Barbora Vitovcova, Jiri Soukup, Hana Vosmikova, Zuzana Pleskacova, Adam Skarka, Michael Christian Bartos, Petr Krupa, Petra Kasparova, Jiri Petera, Emil Rudolf
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with complex signaling patterns
Externí odkaz:
https://doaj.org/article/964b88145a47461bb95f1a49a365e2b5
Autor:
Zuzana Pleskacova, Michael Bartos, Hana Vosmikova, Rafael Dolezal, Petr Krupa, Barbora Vitovcova, Petra Kasparova, Emil Rudolf, Veronika Skarkova, Denisa Pohankova, Veronika Novotna, Jiri Petera
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1210 (2024)
Background: Although several prognostic factors for survival have been identified in glioblastoma, there are numerous other potential markers (such as hemoglobin) whose role has not yet been confirmed. The aim of this study was to evaluate a wide ran
Externí odkaz:
https://doaj.org/article/ab1d1b26cf1b4391bed3f87122d98f20
Autor:
Jiri Soukup, Lucie Gerykova, Anjali Rachelkar, Helena Hornychova, Michael Christian Bartos, Petr Krupa, Barbora Vitovcova, Zuzana Pleskacova, Petra Kasparova, Katerina Dvorakova, Veronika Skarkova, Jiri Petera
Publikováno v:
Diagnostics, Vol 13, Iss 15, p 2546 (2023)
Histological identification of dispersed glioma cells in small biopsies can be challenging, especially in tumours lacking the IDH1 R132H mutation or alterations in TP53. We postulated that immunohistochemical detection of proteins expressed preferent
Externí odkaz:
https://doaj.org/article/d7be2a049cff41569d5bf51ef8f2b6ab
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5324 (2020)
Glioblastoma multiforme (GBM) represents approximately 60% of all brain tumors in adults. This malignancy shows a high biological and genetic heterogeneity associated with exceptional aggressiveness, leading to a poor survival of patients. This revie
Externí odkaz:
https://doaj.org/article/c5dff8f93a1f4adb9d325f1d92d4e98c
Autor:
Veronika Skarkova, Marketa Krupova, Barbora Vitovcova, Adam Skarka, Petra Kasparova, Petr Krupa, Vera Kralova, Emil Rudolf
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4630 (2019)
Purpose: Primary cell lines are a valuable tool for evaluation of tumor behavior or sensitivity to anticancer treatment and appropriate dissociation of cells could preserve genomic profile of the original tissue. The main aim of our study was to comp
Externí odkaz:
https://doaj.org/article/1375bba21e7e48a4ac041389f01aa9fc
Publikováno v:
Cells, Vol 8, Iss 3, p 234 (2019)
Chemoresistance has been found in all malignant tumors including colorectal carcinoma (CRC). Nowadays chemoresistance is understood as a major reason for therapy failure, with consequent tumor growth and spreading leading ultimately to the patient’
Externí odkaz:
https://doaj.org/article/25a9ee66e81846a994bb58af3acdf5e2
Autor:
Jiri Soukup, Monika Manethova, Hana Faistova, Lukas Krbal, Barbora Vitovcova, Helena Hornychova, Jan Drugda, Tomas Cesak, David Netuka, Filip Gabalec, Ales Ryska
Publikováno v:
Histopathology. 81:799-807
Pitx2 is a transcription factor responsible for establishment of the right-left axis and development of the gut and pituitary. In mouse embryos, Pitx2 is expressed in the greater curvature of the stomach and midgut. Previously, Pitx2 was studied in p
Autor:
Veronika Skarkova, Barbora Vitovcova, Petra Matouskova, Monika Manethova, Petra Kazimirova, Adam Skarka, Veronika Brynychova, Pavel Soucek, Hana Vosmikova, Emil Rudolf
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5146
(1) Background: N-cadherin expression, epithelial-to-mesenchymal transition (EMT) and aggressive biological phenotype of tumor cells are linked although the underlying mechanisms are not entirely clear. (2) Methods: In this study, we used two differe
Autor:
David Netuka, Monika Manethova, Filip Gabalec, Helena Hornychova, Barbora Vitovcova, Ludmila Michnova, Tomas Cesak, Jan Cap, Jiri Soukup, Ales Ryska
Publikováno v:
HistopathologyReferences. 79(3)
AIMS In somatotroph pituitary neuroendocrine tumours (adenomas), a pattern of cytokeratin (CK) 18 expression is used for tumour subclassification, with possible clinical implications. Rare somatotroph tumours do not express CK 18. We aimed to charact
Autor:
Barbora Vítovcová, Veronika Skarková, Radim Havelek, Jiří Soukup, Ananya Pande, Kateřina Caltová, Emil Rudolf
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Glioblastoma multiforme (GBM) belongs to most aggressive and invasive primary brain tumor in adults whose prognosis and survival remains poor. Potential new treatment modalities include targeting the cytoskeleton. In our study, we demonstrat
Externí odkaz:
https://doaj.org/article/c47cc9fa09f44377be5987321e1967de