Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Barbora, Szotáková"'
Autor:
Nikola Rychlá, Martina Navrátilová, Eliška Kohoutová, Lucie Raisová Stuchlíková, Karolína Štěrbová, Josef Krátký, Petra Matoušková, Barbora Szotáková, Lenka Skálová
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-11 (2024)
Abstract Carbonyl-reducing enzymes (CREs) catalyse the reduction of carbonyl groups in many eobiotic and xenobiotic compounds in all organisms, including helminths. Previous studies have shown the important roles of CREs in the deactivation of severa
Externí odkaz:
https://doaj.org/article/5757a5985b1d4931a16eb602e217b7e7
Autor:
Antonio Pavičić, Markéta Zajíčková, Michaela Šadibolová, Gabriela Svobodová, Petra Matoušková, Barbora Szotáková, Lenka Langhansová, Petr Maršík, Lenka Skálová
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-10 (2023)
Abstract Most drugs used in the treatment of helminthiasis in humans and animals have lost their efficacy due to the development of drug-resistance in helminths. Moreover, since anthelmintics, like many pharmaceuticals, are now recognized as hazardou
Externí odkaz:
https://doaj.org/article/768d784900b640ea913dc2883927a4d2
Autor:
Pavlína Kellerová, Lucie Raisová Stuchlíková, Petra Matoušková, Karolína Štěrbová, Jiří Lamka, Martina Navrátilová, Ivan Vokřál, Barbora Szotáková, Lenka Skálová
Publikováno v:
Veterinary Research, Vol 51, Iss 1, Pp 1-17 (2020)
Abstract The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g. cytochromes P450 (
Externí odkaz:
https://doaj.org/article/fcef1c6e6dee49ce88c29696feba82c4
Autor:
Vokřál, Ivan, Michaela, Šadibolová, Radka, Podlipná, Jiří, Lamka, Lukáš, Prchal, Dominika, Sobotová, Kateřina, Lokvencová, Barbora, Szotáková, Lenka, Skálová
Publikováno v:
In Ecotoxicology and Environmental Safety March 2019 169:944-949
Autor:
Petra Matoušková, Lenka Lecová, Roz Laing, Diana Dimunová, Heiko Vogel, Lucie Raisová Stuchlíková, Linh Thuy Nguyen, Pavlína Kellerová, Ivan Vokřál, Jiří Lamka, Barbora Szotáková, Marián Várady, Lenka Skálová
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 3, Pp 420-429 (2018)
UDP-glycosyltransferases (UGT), catalysing conjugation of UDP-activated sugar donors to small lipophilic chemicals, are widespread in living organisms from bacteria to fungi, plant, or animals. The progress of genome sequencing has enabled an assessm
Externí odkaz:
https://doaj.org/article/91d5de2796d44a0da5a5dadbc53bc0ed
Autor:
Lucie Raisová Stuchlíková, Petra Matoušková, Ivan Vokřál, Jiří Lamka, Barbora Szotáková, Anna Sečkařová, Diana Dimunová, Linh Thuy Nguyen, Marián Várady, Lenka Skálová
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 1, Pp 50-58 (2018)
Haemonchus contortus (family Trichostrongylidae, Nematoda), a hematophagous gastrointestinal parasite found in small ruminants, has a great ability to develop resistance to anthelmintic drugs. We studied the biotransformation of the three benzimidazo
Externí odkaz:
https://doaj.org/article/2503c274010a4fb996178a272d7add6d
Autor:
Vladimír Kubíček, Lenka Skálová, Adam Skarka, Věra Králová, Jana Holubová, Jana Štěpánková, Zdeněk Šubrt, Barbora Szotáková
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Flubendazole (FLU), an anthelmintic drug of benzimidazole type, is now considered a promising anti-cancer agent due to its tubulin binding ability and low system toxicity. The present study was aimed at determining more information about FLU reductio
Externí odkaz:
https://doaj.org/article/02afe841c66e4d86826b5a44424b5c57
Autor:
Egle Milia, Simonetta Maria Bullitta, Giorgio Mastandrea, Barbora Szotáková, Aurélie Schoubben, Lenka Langhansová, Marina Quartu, Antonella Bortone, Sigrun Eick
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 425 (2021)
There is an increasing interest in revisiting plants for drug discovery, proving scientifically their role as remedies. The aim of this review was to give an overview of the ethnopharmacological uses of Pistacia lentiscus L. (PlL) leaves and fruits,
Externí odkaz:
https://doaj.org/article/ba2dcca5d0f64e16babc7460dd543531
Autor:
Martina Navrátilová, Lucie Raisová Stuchlíková, Kateřina Moťková, Barbora Szotáková, Lenka Skálová, Lenka Langhansová, Radka Podlipná
Publikováno v:
Molecules, Vol 25, Iss 16, p 3655 (2020)
In recent years interest has grown in the occurrence and the effects of pharmaceuticals in the environment. The aim of this work is to evaluate the risk of fertilizing crops with manure from livestock treated with anthelmintics. The present study was
Externí odkaz:
https://doaj.org/article/a6d2ee9e785041b7b8a1370ce305fd45
Autor:
Egle Milia, Marianna Usai, Barbora Szotáková, Marie Elstnerová, Věra Králová, Guy D’hallewin, Ylenia Spissu, Antonio Barberis, Mauro Marchetti, Antonella Bortone, Vincenzo Campanella, Giorgio Mastandrea, Lenka Langhansová, Sigrun Eick
Publikováno v:
Antibiotics, Vol 9, Iss 6, p 281 (2020)
Background: Given the increasing request for natural pharmacological molecules, this study assessed the antimicrobial capacity of Pistacia lentiscus L. essential oil (PLL-EO) obtained from the leaves of wild plants growing in North Sardinia (Italy) t
Externí odkaz:
https://doaj.org/article/5b48943ac0054835b3c7eab764ac343b