Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

Autor: Sechrest ER; Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, United States., Barbera RJ; Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, United States., Ma X; Department of Ophthalmology, University of Florida, Gainesville, FL, United States., Dyka F; Department of Ophthalmology, University of Florida, Gainesville, FL, United States., Ahn J; Department of Chemistry, University of Virginia, Charlottesville, VA, United States., Brothers BA; Department of Biochemistry, West Virginia University, Morgantown, WV, United States., Cahill ME; Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, United States.; Department of Biology, West Virginia University, Morgantown, WV, United States., Hall I; Department of Natural Sciences, Fairmont State University, Fairmont, WV, United States., Baehr W; Department of Ophthalmology, John A. Moran Eye Center, University of Utah Health Science Center, Salt Lake City, UT, United States.; Department of Neurobiology and Anatomy, University of Utah Health Science Center, Salt Lake City, UT, United States.; Department of Biology, University of Utah, Salt Lake City, UT, United States., Deng WT; Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, United States.; Department of Biochemistry, West Virginia University, Morgantown, WV, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2024 Feb 12; Vol. 18, pp. 1368089. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).