Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Barbara de la Pena Avalos"'
Autor:
Sribalasubashini Muralimanoharan, Ross Shamby, Nicholas Stansbury, Robert Schenken, Barbara de la Pena Avalos, Samin Javanmardi, Eloise Dray, Patrick Sung, Thomas G. Boyer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Uterine fibroid (UF) driver mutations in Mediator complex subunit 12 (MED12) trigger genomic instability and tumor development through unknown mechanisms. Herein, we show that MED12 mutations trigger aberrant R-loop-induced replication stres
Externí odkaz:
https://doaj.org/article/c0125838d6f34460b746424e73028e09
Autor:
Clare E. Murray, Anand V. R. Kornepati, Carlos Ontiveros, Yiji Liao, Bárbara de la Peña Avalos, Cody M. Rogers, Zexuan Liu, Yilun Deng, Haiyan Bai, Suresh Kari, Alvaro S. Padron, Jacob T. Boyd, Ryan Reyes, Curtis A. Clark, Robert S. Svatek, Rong Li, Yanfen Hu, Meiling Wang, José R. Conejo-Garcia, Lauren A. Byers, Kavya Ramkumar, Anil K. Sood, Jung-Min Lee, Christin E. Burd, Ratna K. Vadlamudi, Harshita B. Gupta, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Background Aside from the canonical role of PDL1 as a tumour surface-expressed immune checkpoint molecule, tumour-intrinsic PDL1 signals regulate non-canonical immunopathological pathways mediating treatment resistance whose significance, me
Externí odkaz:
https://doaj.org/article/324b033e9fa34bbcab45721b8054a03a
Autor:
Prajwal C Boddu, Abhishek Gupta, Rahul Roy, Barbara De La Pena Avalos, Ane Olazabal Herrero, Nils Neuenkirchen, Josh Zimmer, Namrata Chandhok, Darren King, Yashuhito Nannya, Seishi Ogawa, Haifan Lin, Matthew Simon, Eloise Dray, Gary Kupfer, Amit K. Verma, Karla M. Neugebauer, Manoj M Pillai
Publikováno v:
bioRxiv
Transcription and splicing of pre-messenger RNA are closely coordinated, but how this functional coupling is disrupted in human disease remains unexplored. Here, we investigated the impact of non-synonymous mutations in SF3B1 and U2AF1, two commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc52bc1a58f7506bad42b4fd807506b
https://europepmc.org/articles/PMC9994134/
https://europepmc.org/articles/PMC9994134/
Autor:
Patrick J. Conway, Bárbara De La Peña Avalos, Jonathan Dao, Sebastian Montagnino, Dmytro Kovalskyy, Eloise Dray, Daruka Mahadevan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 55, Iss , Pp 101014- (2024)
Chemotherapy induced polyploidy is a mechanism of inherited drug resistance resulting in an aggressive disease course in cancer patients. Alisertib, an Aurora Kinase A (AK-A) ATP site inhibitor, induces cell cycle disruption resulting in polyaneuploi
Externí odkaz:
https://doaj.org/article/fdf3550c509b4ad3a071ef8341bf288c
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract The Eyes Absent (EYA) family of proteins is an atypical group of four dual-functioning protein phosphatases (PP), which have been linked to many vital cellular processes and organogenesis pathways. The four family members of this PP family p
Externí odkaz:
https://doaj.org/article/84a501a5d1624c18945c54c7315e35a6