Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Barbara Zielińska-Psuja"'
Autor:
Karina Sommerfeld-Klatta, Magdalena Łukasik-Głębocka, Sylwia Kobyłka, Barbara Zielińska-Psuja
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 2, Pp 335-340 (2023)
Valproic acid (VPA) is a broad-spectrum anticonvulsant drug. Its mechanism of action includes enhancing GABAergic transmission, blocking voltage-gated sodium channels, and affecting dopaminergic and serotonergic transmission (1). The mechanism of VPA
Externí odkaz:
https://doaj.org/article/945a3f4974274cd98c380ed6e1654d6e
Autor:
Karina Sommerfeld-Klatta, Magdalena Łukasik-Głębocka, Ewelina Krawczak, Anna Stodolska, Barbara Zielińska-Psuja
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 2, Pp 327-333 (2023)
Quetiapine (QT) belongs to the second generation of antipsychotics. It is mostly used to treat depression, bipolar disorder, and schizophrenia. During biotransformation via myeloperoxidase (MPO) QT is oxidized to quinoneimine and a reactive radical,
Externí odkaz:
https://doaj.org/article/766a8745375e47f7b61e8b01dbd36fa0
Autor:
Karina Sommerfeld-Klatta, Wiktoria Jiers, Magdalena Łukasik-Głębocka, Artur Tezyk, Klaudia Dolińska-Kaczmarek, Kamil Walter, Paweł Świderski, Szymon Rzepczyk, Barbara Zielińska-Psuja, Czesław Żaba
Publikováno v:
Toxics, Vol 11, Iss 10, p 872 (2023)
In recent years, the administration of fentanyl (FNTL) implicitly in transdermal drug delivery systems (TDDS) has vastly increased in chronic pain treatment. Non-medical and uncontrolled use of FNTL in TFDS (transdermal fentanyl delivery systems) may
Externí odkaz:
https://doaj.org/article/1a0b89b315df4080ab9d76cb6efe90b9
Autor:
Szymon Rzepczyk, Paweł Świderski, Karina Sommerfeld-Klatta, Artur Tezyk, Magdalena Łukasik-Głębocka, Barbara Zielińska-Psuja, Zbigniew Żaba, Czesław Żaba
Publikováno v:
Toxics, Vol 11, Iss 8, p 652 (2023)
Unconventional (alternative, natural) medicine in Poland and worldwide includes hundreds of non-scientifically verified “treatment” modalities. Among the most popular are biological therapies using chemical or natural compounds administered with
Externí odkaz:
https://doaj.org/article/6073f3a4afc445ba8c89dc54d3769c62
Autor:
Karina Sommerfeld-Klatta, Barbara Zielińska-Psuja, Marta Karaźniewcz-Łada, Franciszek K. Główka
Publikováno v:
Molecules, Vol 25, Iss 21, p 5083 (2020)
The review presents data from the last few years on bioanalytical methods used in therapeutic drug monitoring (TDM) of the 1st–3rd generation and the newest antiepileptic drug (AEDs) cenobamate in patients with various forms of seizures. Chemical c
Externí odkaz:
https://doaj.org/article/5b8a76cbb4784e81a6a85ca49ff4c2da
Publikováno v:
International Journal of Occupational Medicine and Environmental Health, Vol 26, Iss 5, Pp 802-812 (2013)
Objectives: The aim of the study was to evaluate the influence of acetylsalicylic acid (ASA) on benzene hematotoxicity in rats. Materials and Methods: The study was carried out on rats exposed for 2, 4 and 8 weeks to benzene vapour at a conentration
Externí odkaz:
https://doaj.org/article/cc4ff5d9be6c4076a9c1bb01ef55cbcf
Publikováno v:
Journal of Medical Science, Vol 83, Iss 1 (2014)
Introduction. Ethylene glycol (EG) is relatively nontoxic but undergoes a multi-step oxidation to toxic metabolites, aldehydes and acids. The accumulation of organic acids, mainly glycolates, leads to the development of profound, life-threatening met
Externí odkaz:
https://doaj.org/article/feb6078faad44be598a46826c67edabd
Autor:
Jan Krzysztof Nowak, Patrycja Krzyżanowska-Jankowska, Sławomira Drzymała-Czyż, Joanna Goździk-Spychalska, Irena Wojsyk-Banaszak, Wojciech Skorupa, Ewa Sapiejka, Anna Miśkiewicz-Chotnicka, Jan Brylak, Barbara Zielińska-Psuja, Aleksandra Lisowska, Jarosław Walkowiak
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 2; Pages: 462
Journal of Clinical Medicine, Vol 11, Iss 462, p 462 (2022)
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 11, Iss 462, p 462 (2022)
Journal of Clinical Medicine
Background: We aimed to assess a liposomal fat-soluble vitamin formulation containing vitamin K2 with standard treatment in cystic fibrosis (CF). Methods: A multi-center randomized controlled trial was carried out in 100 pancreatic-insufficient patie
Publikováno v:
Humanexperimental toxicology. 41
Ethylene glycol (EG), in addition to its neurotoxic and nephrotoxic effects, evokes oxidative stress. The aim of this study was to assess the influence of the ethylene glycol on the biochemical indicators and oxidoreductive balance of patients treate
Autor:
Jan K. Nowak, Paulina Sobkowiak, Sławomira Drzymała-Czyż, Patrycja Krzyżanowska-Jankowska, Ewa Sapiejka, Wojciech Skorupa, Andrzej Pogorzelski, Agata Nowicka, Irena Wojsyk-Banaszak, Szymon Kurek, Barbara Zielińska-Psuja, Aleksandra Lisowska, Jarosław Walkowiak
Publikováno v:
Nutrients; Volume 13; Issue 12; Pages: 4554
Nutrients
Nutrients, Vol 13, Iss 4554, p 4554 (2021)
Nutrients
Nutrients, Vol 13, Iss 4554, p 4554 (2021)
Fat-soluble vitamin deficiency remains a challenge in cystic fibrosis (CF), chronic pancreatitis, and biliary atresia. Liposomes and cyclodextrins can enhance their bioavailability, thus this multi-center randomized placebo-controlled trial compared