Mycophenolate and azathioprine efficacy in interstitial lung disease: a systematic review and meta-analysis

Autor: Sally Singh, Mark Jones, Michael Kreuter, Maria Molina-Molina, Imre Noth, Andrew Wilson, Martin Brutsche, Naftali Kaminski, Gary M Hunninghake, Michael Keane, Nazia Chaudhuri, Ian Forrest, Bruno Crestani, Fernando J Martinez, Mohsen Sadatsafavi, Luca Richeldi, Antje Prasse, Fasihul Khan, Iain Stewart, Steve Jones, Gisli Jenkins, Gauri Saini, David Turner, Killian Hurley, Lucilla Piccari, Andrew Palmer, Joseph A Lasky, Simon Hart, Joyce Lee, Anthony Gordon, John Blaikley, Kirsty Hett, Helmut Prosch, Elisabeth Bendstrup, Christopher Huntley, Helen Parfrey, Huzaifa Adamali, Paul Beirne, Stephen Bianchi, George Chalmers, Sophie Fletcher, Peter George, Michael Gibbons, Mark Spears, Laura Fabbri, Felix Chua, Michael Henry, Cormac McCarthy, Sabrina Paganoni, Joseph Jacob, Mark Toshner, Bibek Gooptu, Andrew Briggs, Philip L Molyneaux, Athol Wells, Charlotte Summers, Leticia Kawano-Dourado, Ian Glaspole, Melanie Quintana, Christopher J Ryerson, Paolo Spagnolo, Francesco Bonella, Carisi Anne Polanczyk, Anjali Crawshaw, Laurence Pearmain, Avinash Anil Nair, Raphaël Borie, Alexandre Biasi Cavalcanti, Emanuela Falaschetti, Jonathan Chung, James Eaden, Kate Johnson, Shaney Barratt, Chris Ryerson, Juergen Behr, Andreas Guenther, Nik Hirani, Karin Storrer, Deepak Talwar, Claudia Ravaglia, Katerina Antoniou, Sara Freitas, Carlo Vancheri, Laura Price, Amanda Goodwin, Daniel Chambers, Gunnar Gudmundsson, Roger Lewis, Ingrid Cox, Anne Holland, Erica Farrand, Argyrios Tzouvelekis, Rui Rolo, Duncan Richards, Larissa Schwarzkopf, Sabina Guler, Devesh Dhasmana, Claudia Valenzuela, John S Kim, Louise Crowley, Lisa Watson, Amanda Bravery, Elisabetta Balestro, Wendy Adams, Francesco Lombardi, Ali Mojibian, Ana Etges, Ana Sousa Marcelino Boshoff, Anne Bergeron Anna-MariaHoffmann-Vold, Athina Trachalaki, Barbara Wendelberger, Bhavika Kaul Ben Hope-Gill, Bruno Baldi, Carlos Robalo, Chris Grainge, Christophe von Garnier, Conal Hayton, Dapeng Wang, Daphne Bablis, David Thicket, Deji Adegunsoye, Devaraj Anand, Dhruv Parek, Diane Griffiths, Eliana Santucci, Eliza Tsitoura, Emma Karlsen, Ena Gupta, Harold Collard, Hernan Fainberg, Iazsmin Bauer-Ventura, Irina Strambu, Jacobo Sellares, Janet Johnston, Jeff Swigris, Karina Negrelli, Katarzyna Lewandowska, Katrin Hostettler, Kerri Johannson, Liam Galvin, Lisa G. Spencer, Manuela Funke Chambour, Marlies Wijsenbeek-Lourens, Martina Vasakova, Milena Man Iuliu Hatieganu, Nick Weatherley, Ovidiu Fira Mladinescu Victor Babes, Peter Bryce, Pilar Rivera Ortega, Radu Crisan-Dabija, Rahul Maida, Sara Piciucchi, Shama Malik, Simone Dal Corso, Stefan Stanel

Publikováno v: BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)

Objectives Mycophenolate mofetil (MMF) and azathioprine (AZA) are immunomodulatory treatments in interstitial lung disease (ILD). This systematic review aimed to evaluate the efficacy of MMF or AZA on pulmonary function in ILD.Design Population inclu

Externí odkaz: https://doaj.org/article/2ac47dada7d648a4a2a2a9b8b2f6ab10

ICU‐free days as a more sensitive primary outcome for clinical trials in critically ill pediatric patients

Autor: Hanjin Cho, Barbara Wendelberger, Marianne Gausche‐Hill, Henry E Wang, Matthew Hansen, Nichole Bosson, Roger J. Lewis

Publikováno v: Journal of the American College of Emergency Physicians Open, Vol 2, Iss 4, Pp n/a-n/a (2021)

Abstract Background Our objective was to assess the association between intensive care unit (ICU)‐free days and patient outcomes in pediatric prehospital care and to evaluate whether ICU‐free days is a more sensitive outcome measure for emergency

Externí odkaz: https://doaj.org/article/89311e5867824e1a91a636a330fa80be

Design of a novel clinical trial of prehospital pediatric airway management

Autor: Nichole Bosson, Matthew Hansen, Marianne Gausche-Hill, Roger J Lewis, Barbara Wendelberger, Manish I Shah, John M VanBuren, Henry E Wang

Publikováno v: Clinical Trials. 19:62-70

Emergency Medical Services personnel are often the first to intervene in the care of critically ill children. Airway management is a fundamental step in prehospital resuscitation, yet there is significant variation in current prehospital airway manag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaf8507df418f2e5ea53ffa8d27ccb6
https://doi.org/10.1177/17407745211059855

Latent disease models estimate symptom onset in familial frontotemporal lobar degeneration and enable novel designs for early‐stage clinical trials

Autor: Bradley F. Boeve, Amy Wolf, Yann Cobigo, Chiadi U. Onyike, Adam L. Boxer, Sheng‐Yang Matthew Goh, Howard J. Rosen, Melanie Quintana, Barbara Wendelberger, Hilary W. Heuer, Adam M. Staffaroni, Julio C. Rojas

Publikováno v: Alzheimer's & Dementia. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fd31acb93fc3309f1c8b6e3f725d83f
https://doi.org/10.1002/alz.045854