Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Barbara Thalenfeld"'
Autor:
Yaron Ilan, M Gomori, Barbara Thalenfeld, Dean Engelhardt, Eran Elinav, Oren Shibolet, Ruslana Alper, Elazar Rabbani, M. Margalit, Miri Sklair-Levy, Orit Pappo
Publikováno v:
The Journal of Pathology. 209:121-128
The aim of this study was to determine the effect of adoptive transfer of regulatory natural killer T (NKT) lymphocytes on the metabolic disorder in leptin-deficient ob/ob mice, which feature depletion and defective function of NKT and CD4 lymphocyte
Autor:
Maya, Margalit, Samir, Abu Gazala, Samir Abu, Ghazala, Ruslana, Alper, Eran, Elinav, Athalia, Klein, Victoria, Doviner, Yoav, Sherman, Barbara, Thalenfeld, Dean, Engelhardt, Elazar, Rabbani, Yaron, Ilan
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 289:G917-G925
Concanavalin A (ConA) induces natural killer T (NKT) cell-mediated liver damage. Glucocerebroside (GC) is a naturally occurring glycolipid. Our aims were to determine the effect of GC in a murine model of ConA-induced hepatitis. Mice in groups A and
Autor:
Elazar Rabbani, Oren Shibolet, Ruslana Alper, Eran Elinav, Yaron Ilan, Barbara Thalenfeld, Maya Margalit, Dean Engelhardt, Athalia Klein
Publikováno v:
International Journal of Cancer. 115:443-449
NKT cells are a regulatory subset of T lymphocytes with immune modulatory effects and an important role in anti-tumor immunity. The feasibility of “ex-vivo education” of NKT cells has recently been demonstrated. To evaluate the anti-tumor effect
Autor:
Lydia Zolotarov, Shivti Trop, Elazar Rabbani, Yaron Ilan, Dean Engelhardt, Oren Shibolet, Barbara Thalenfeld, Ruslana Alper
Publikováno v:
Clinical Immunology. 111:82-92
The liver was previously suggested as a site of lymphocyte clearance. Liver-associated lymphocytes that express NK1.1 marker (NKT LAL) play a role in immune modulation. Aim: To determine the role of the liver and of NKT LAL in determining the CD4+/CD
Autor:
Barbara Thalenfeld, Yaron Ilan, Dean Engelhardt, Elazar Rabbani, Lydia Zolotarov, Ruslana Alper, Oren Shibolet, Athalia Klein, Yossef Kalish
Publikováno v:
Journal of Leukocyte Biology. 75:76-86
T lymphocyte-expressing natural killer (NK) cell markers (NKT cells) play a role in immune regulation. Our aim was to evaluate the in vivo effect of adoptive transfer of immune-programmed NKT cells. Colitis was induced in C57/B6 mice by 2,4,6-trinitr
Autor:
Eran Elinav, Maya Margalit, Dean Engelhardt, Yaron Ilan, Oren Shibolet, Roslana Alper, Miriam Sklair-Levy, Elazar Rabbani, Orit Pappo, Moshe Gomori, Barbara Thalenfeld
Publikováno v:
The Journal of pathology. 208(1)
Non-alcoholic steatohepatitis (NASH) is a common cause of cryptogenic cirrhosis in the Western world. In an animal model of NASH, leptin-deficient ob/ob mice present with alterations in number and function of hepatic NKT and peripheral CD4 lymphocyte
Autor:
Athalia Klein, Barbara Thalenfeld, Oren Shibolet, Eran Israeli, Elazar Rabbani, Yaron Ilan, Alaa Melhem, Nilla Hemed, Orit Pappo, Rifaat Safadi, Dean Engelhardt
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 24(4)
Background: Anti-viral immunity can be modulated via oral feeding of viral proteins. Hepatitis B and C viral (HBV, HCV)-associated hepatocellular injury is mediated by a defective host anti-viral immune response. Aims: To determine the effect of oral
Autor:
Yaron Ilan, Orit Papo, Elazar Rabbani, Barbara Thalenfeld, Aharon Bloch, Nilla Hemed, Oren Shibolet, Athalia Klein, Mina Rowe, Eran Israeli, Rifaat Safadi, Dean Engelhardt, Alaa Melhem, Ruslana Alper, Ori Segol
Publikováno v:
The American journal of gastroenterology. 98(11)
Hepatitis B virus (HBV) is a noncytopathic virus, and hepatocellular injury is mediated by a defective host antiviral immune response. We have previously shown that antiviral immunity can be modulated through oral feeding of viral proteins. The aims
Autor:
Dean Engelhardt, Elazar Rabbani, Oren Shibolet, Lydia Zlotogarov, Yaron Ilan, Barbara Thalenfeld, Ruslana Alper
Publikováno v:
International journal of cancer. 106(2)
Dendritic cells (DCs) are antigen presenting cells that play a role in T-cell activation. Liver-associated natural killer T lymphocytes (NKTs) are a unique subset of lymphocytes that may be important in antitumor immunity. Hepatitis B virus (HBV)-ass
Autor:
Yaron Ilan, Barbara Thalenfeld, Dean Engelhardt, Lydia Zlotogarov, Ruslana Alper, Elazar Rabbani, Oren Shibolet
Publikováno v:
Oncology. 66(4)
Background: Oral immune regulation towards viral proteins was previously shown to modulate the anti-HBV immune response. Adoptive transfer of orally immunomodulated lymphocytes suppressed the growth of hepatocellular carcinoma (HCC) expressing HBsAg