Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Barbara Tenci"'
Autor:
Lorenzo Di Cesare Mannelli, Laura Micheli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Barbara Tenci, Matteo Zanardelli, Jacopo Junio Valerio Branca, Alessandra Pacini, Carla Ghelardini
Publikováno v:
Molecules, Vol 25, Iss 9, p 2117 (2020)
Sarcopenia is a clinical problem associated with several pathological and non-pathological conditions. The aim of the present research is the evaluation of the pharmacological profile of the leucine metabolite β-hydroxy-β-methyl butyrate (HMB) asso
Externí odkaz:
https://doaj.org/article/a69edac2ba8041e2b8729559c2f11a37
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Neuropathies are characterized by a complex response of the central nervous system to injuries. Glial cells are recruited to maintain neuronal homeostasis but dysregulated activation leads to pain signaling amplification and reduces the glial neuropr
Externí odkaz:
https://doaj.org/article/0787dc65ea1448aab812c71116b77adf
Autor:
Carmen Parisio, Carla Ghelardini, Barbara Tenci, Elena Lucarini, Alessandra Toti, Alessandra Pacini, Jacopo Junio Valerio Branca, Laura Micheli, Lorenzo Di Cesare Mannelli, Matteo Zanardelli
Publikováno v:
Molecules
Volume 25
Issue 9
Molecules, Vol 25, Iss 2117, p 2117 (2020)
Volume 25
Issue 9
Molecules, Vol 25, Iss 2117, p 2117 (2020)
Sarcopenia is a clinical problem associated with several pathological and non-pathological conditions. The aim of the present research is the evaluation of the pharmacological profile of the leucine metabolite &beta
hydroxy-&beta
methyl but
hydroxy-&beta
methyl but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a836942c1fc9c15b34b3c6ee69cc36a
Autor:
Barbara Tenci, Mohamad Khatib, Marzia Innocenti, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Laura Micheli, Mario Maresca, Nadia Mulinacci
Publikováno v:
Journal of Ethnopharmacology. 193:456-465
Ethnopharmacological relevance Capparis spinosa L. originates from dry regions of Asia and Mediterranean basin. In traditional medicine of these areas, infusions from caper root are considered to be beneficial for the treatment of rheumatism, gout an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5cecb3b59ff094c2231a9cc422d21f
https://doi.org/10.1016/j.jep.2016.09.032
https://doi.org/10.1016/j.jep.2016.09.032
Autor:
Massimo Gulisano, Gabriele Morucci, Alessandra Pacini, Jacopo Junio Valerio Branca, Ferdinando Paternostro, Mario Maresca, Carla Ghelardini, Barbara Tenci, Lorenzo Di Cesare Mannelli, Roberta Cascella
Cadmium (Cd), a worldwide occupational pollutant, is an extremely toxic heavy metal, capable of damaging several organs, including the brain. Its toxicity has been related to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304e8724aefda341a1782a3b376c2520
http://hdl.handle.net/11568/1053376
http://hdl.handle.net/11568/1053376
Autor:
Lorenzo Di Cesare Mannelli, Carla Ghelardini, Luisa Mattoli, Anna Maidecchi, Matteo Zanardelli, Andrea Lugli, Barbara Tenci
Publikováno v:
Phytomedicine. 22:752-758
Background Tanacetum parthenium L., commonly called Feverfew, is known for anti-inflammatory and anti-migraine properties. Purpose Aimed to individuate new therapeutical strategies to control acute and persistent pain induced by different origins we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00946019086d404fdcf8c28502a4e69d
https://doi.org/10.1016/j.phymed.2015.05.006
https://doi.org/10.1016/j.phymed.2015.05.006
Autor:
Paola Gratteri, Claudiu T. Supuran, Carrie L. Lomelino, Robert McKenna, Barbara Tenci, Silvia Bua, Marta Menicatti, Gianluca Bartolucci, Lorenzo Di Cesare Mannelli, Alessio Nocentini, Carla Ghelardini
Publikováno v:
ACS medicinal chemistry letters. 8(12)
Incorporation of the purine/pyrimidine moieties as tails to classical benzenesulfonamide scaffolds afforded two series of human (h) carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. The compounds were designed according to the molecular hybridization a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78be8efb0975f13a3c290682ec19b38
https://pubmed.ncbi.nlm.nih.gov/29259754
https://pubmed.ncbi.nlm.nih.gov/29259754
Autor:
Claudiu T. Supuran, Matteo Falsini, Alessandro Bonardi, Flavia Varano, Barbara Tenci, Daniela Catarzi, Andrea Angeli, Carla Ghelardini, Vittoria Colotta, Lorenzo Di Cesare Mannelli
Publikováno v:
European journal of medicinal chemistry. 146
Human carbonic anhydrases (hCAs, EC 4.2.1.1) IX and XII are overexpressed in a wide variety of cancers and are considered available drug targets for anti-tumor therapy since their inhibition has been shown to reduce tumor growth and metastasis. A set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f754a6627585db013254587b148d967
https://pubmed.ncbi.nlm.nih.gov/29407972
https://pubmed.ncbi.nlm.nih.gov/29407972
Autor:
Andrea Angeli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Muhammet Tanc, Daniela Catarzi, Flavia Varano, Barbara Tenci, Lucia Squarcialupi, Matteo Falsini, Vittoria Colotta, Claudiu T. Supuran, Marco Betti
Publikováno v:
Journal of medicinal chemistry. 60(14)
In this paper, we describe the discovery of the 3-hydroxyquinazoline-2,4-dione as a useful scaffold to obtain potent inhibitors of the tumor-associated human carbonic anhydrases (hCAs) IX and XII. A set of derivatives (1–29), bearing different subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46453ed09d74c220260767681b8b43a2
https://pubmed.ncbi.nlm.nih.gov/28658574
https://pubmed.ncbi.nlm.nih.gov/28658574
Autor:
Ann Maria Clemente, Laura Micheli, Barbara Tenci, Lorenzo Di Cesare Mannelli, Alessia Vona, Matteo Zanardelli, Andrea Lapucci, Carla Ghelardini, Paola Failli, Francesca Corti
Oxaliplatin therapy of colorectal cancer induces a dose-dependent neuropathic syndrome in 50% of patients. Pharmacological treatments may offer limited relief; scientific efforts are needed for new therapeutic approaches. Therefore we evaluated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90888cb328930deda7f72bd292a7330a
http://hdl.handle.net/2158/1108297
http://hdl.handle.net/2158/1108297