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pro vyhledávání: '"Barbara Temporelli"'
Autor:
Edward F. Elslager, Leslie M. Werbel, Leo Rane, Judith L. Johnson, Barbara Temporelli, Donald F. Worth, Marland P. Hutt, Patricia Jacob
Publikováno v:
Journal of Medicinal Chemistry. 22:1247-1257
Oxidation of an array of 2,4-diamino-6-(arylthio)quinazolines provided the corresponding arylsulfinyl and arylsulfonyl analogues. A variety of these nonclassical analogues of methotrexate exhibited suppressive antimalarial activity superior to that o