A genetic screen in Drosophila reveals an unexpected role for the KIP1 ubiquitination-promoting complex in male fertility.

Autor: Weizhe Li, Jinqing Liang, Patricia Outeda, Stacey Turner, Barbara T Wakimoto, Terry Watnick

Publikováno v: PLoS Genetics, Vol 16, Iss 12, p e1009217 (2020)

A unifying feature of polycystin-2 channels is their localization to both primary and motile cilia/flagella. In Drosophila melanogaster, the fly polycystin-2 homologue, Amo, is an ER protein early in sperm development but the protein must ultimately

Externí odkaz: https://doaj.org/article/3de5abd451c94ce59dfb87e8c77f0287

The Deadbeat Paternal Effect of Uncapped Sperm Telomeres on Cell Cycle Progression and Chromosome Behavior in Drosophila melanogaster

Autor: Glenn K. Yasuda, Takuo Yamaki, Barbara T. Wakimoto

Publikováno v: Genetics. 203:799-816

Telomere-capping complexes (TCCs) protect the ends of linear chromosomes from illegitimate repair and end-to-end fusions and are required for genome stability. The identity and assembly of TCC components have been extensively studied, but whether TCC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e64db3857cef13e0d26498a1809043
https://doi.org/10.1534/genetics.115.182436

Facilitating Long-Term Changes in Student Approaches to Learning Science

Autor: Emile Pitre, Catharine Hoffman Beyer, Nevena Lalic, Paul D. Sampson, Jon E. Peterson, Brian J. Buchwitz, Barbara T. Wakimoto

Publikováno v: CBE Life Sciences Education

Undergraduates entering science curricula differ greatly in individual starting points and learning needs. The fast pace, high enrollment, and high stakes of introductory science courses, however, limit students’ opportunities to self-assess and mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcd69274004d3739084d3a593ade144
https://doi.org/10.1187/cbe.12-01-0011

Sperm plasma membrane breakdown during Drosophila fertilization requires Sneaky, an acrosomal membrane protein

Autor: Blaine T. Bafus, Barbara T. Wakimoto, Kathleen L. Wilson, Karen R. Fitch

Publikováno v: Development. 133:4871-4879

Fertilization typically involves membrane fusion between sperm and eggs. In Drosophila, however, sperm enter eggs with membranes intact. Consequently, sperm plasma membrane breakdown (PMBD) and subsequent events of sperm activation occur in the egg c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbf6e5a60b4f9362c69f90d554e9536
https://doi.org/10.1242/dev.02671

Genetic Dissection of Meiotic Cytokinesis inDrosophilaMales

Autor: Barbara T. Wakimoto, Silvia Bonaccorsi, Rebecca M. Farkas, Maria Grazia Giansanti, Dan L. Lindsley, Margaret T. Fuller, Maurizio Gatti

Publikováno v: Molecular biology of the cell 154 (2004): 23–34.
info:cnr-pdr/source/autori:Giansanti MG, Farkas RM, Bonaccorsi S, Lindsley DL, Wakimoto B, Fuller MT, Gatti M./titolo:Genetic dissection of meiotic cytokinesis in Drosophila males./doi:/rivista:Molecular biology of the cell/anno:2004/pagina_da:23/pagina_a:34/intervallo_pagine:23–34/volume:154
Molecular biology of the cell 15 (2004): 2509–2522. doi:10.1091/mbc.E03-08-0603
info:cnr-pdr/source/autori:Giansanti MG;Farkas RM;Bonaccorsi S; Lindsley DL; Wakimoto BT; Fuller MT; Gatti M./titolo:Genetic dissection of meiotic cytokinesis in Drosophila males./doi:10.1091%2Fmbc.E03-08-0603/rivista:Molecular biology of the cell/anno:2004/pagina_da:2509/pagina_a:2522/intervallo_pagine:2509–2522/volume:15

We have used Drosophila male meiosis as a model system for genetic dissection of the cytokinesis mechanism. Drosophila mutants defective in meiotic cytokinesis can be easily identified by their multinucleate spermatids. Moreover, the large size of me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b35482bec381fc8184b490d016d747d
https://doi.org/10.1091/mbc.e03-08-0603