Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Barbara Sherry"'
Autor:
Haruki Watanabe, Minakshi Rana, Myoungsun Son, Pui Yan Chiu, Yurong Fei-Bloom, Kwangmin Choi, Betty Diamond, Barbara Sherry
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-22 (2024)
Abstract Background Sepsis survivors exhibit immune dysregulation that contributes to poor long-term outcomes. Phenotypic and functional alterations within the myeloid compartment are believed to be a contributing factor. Here we dissect the cellular
Externí odkaz:
https://doaj.org/article/cd20bcf3fc7f4dae8d46999c17da69b2
Autor:
Deepti Gadi, Stephen P. Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M. Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C. Fisher, Philippe Armand, Matthew S. Davids, Scott Rodig, Barbara Sherry, Jennifer R. Brown
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract PI3Kδ inhibitors are approved for the therapy of B cell malignancies, but their clinical use has been limited by unpredictable autoimmune toxicity, despite promising efficacy and evidence that toxicity is associated with improved clinical o
Externí odkaz:
https://doaj.org/article/94914f0b3bca45c9ad51c3edd14b1ac9
Autor:
Ibrahim T. Mughrabi, Mahendar Ochani, Mirza Tanovic, Ping Wang, Betty Diamond, Barbara Sherry, Valentin A. Pavlov, Seza Ozen, Daniel L. Kastner, Jae Jin Chae, Yousef Al-Abed
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-11 (2022)
Abstract Background Autoinflammatory diseases, a diverse group of inherited conditions characterized by excessive innate immune activation, have limited therapeutic options. Neuroimmune circuits of the inflammatory reflex control innate immune overac
Externí odkaz:
https://doaj.org/article/31c2573a5b13408bb668d631563ddf84
Autor:
Ahmad Altiti, Mingzhu He, Sonya VanPatten, Kai Fan Cheng, Umair Ahmed, Pui Yan Chiu, Ibrahim T. Mughrabi, Bayan Al Jabari, Ronald M. Burch, Kirk R. Manogue, Kevin J. Tracey, Betty Diamond, Christine N. Metz, Huan Yang, LaQueta K. Hudson, Stavros Zanos, Myoungsun Son, Barbara Sherry, Thomas R. Coleman, Yousef Al-Abed
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The rapid protease degradation of peptides is currently limiting their therapeutic utility. Here, the authors report functionalised thiocarbazate scaffolds as precursors of aza-amino acids that can be integrated in peptide sequences, extending their
Externí odkaz:
https://doaj.org/article/a48c24524daa4e5cb8838c0018607cb6
Autor:
Byeongho Jung, Gerardo Ferrer, Pui Yan Chiu, Rukhsana Aslam, Anita Ng, Florencia Palacios, Michael Wysota, Martina Cardillo, Jonathan E. Kolitz, Steven L. Allen, Jacqueline C. Barrientos, Kanti R. Rai, Nicholas Chiorazzi, Barbara Sherry
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Chronic lymphocytic leukemia (CLL) results from expansion of a CD5+ B cell clone that requires interactions with other cell types, including T cells. Moreover, patients with CLL have elevated levels of circulating IL-17A+ and IL-17F+ CD4+ T (Th17) ce
Externí odkaz:
https://doaj.org/article/1c7c156072fb450faf5d7195756c1e4c
Autor:
Sylvia H. Ferguson, Derek M. Foster, Barbara Sherry, Scott T. Magness, Dahlia M. Nielsen, Jody L. Gookin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 1, Pp 1-20 (2019)
Background & Aims: The epithelial response is critical for intestinal defense against Cryptosporidium, but is poorly understood. To uncover the host strategy for defense against Cryptosporidium, we examined the transcriptional response of intestinal
Externí odkaz:
https://doaj.org/article/32aa2df03fe9482eab7563eb8a4c4ed7
Autor:
Minakshi Rana, Yurong Fei-Bloom, Myoungsun Son, Andrea La Bella, Mahendar Ochani, Yaakov A. Levine, Pui Yan Chiu, Ping Wang, Sangeeta S. Chavan, Bruce T. Volpe, Barbara Sherry, Betty Diamond
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Patients surviving a septic episode exhibit persistent immune impairment and increased mortality due to enhanced vulnerability to infections. In the present study, using the cecal ligation and puncture (CLP) model of polymicrobial sepsis, we addresse
Externí odkaz:
https://doaj.org/article/4a0ebd6aa74c41bb97bd020ab28a5ab7
Autor:
Manojkumar Gunasekaran, Prodyot K. Chatterjee, Andrew Shih, Gavin H. Imperato, Meghan Addorisio, Gopal Kumar, Annette Lee, John F. Graf, Dan Meyer, Michael Marino, Christopher Puleo, Jeffrey Ashe, Maureen A. Cox, Tak W. Mak, Chad Bouton, Barbara Sherry, Betty Diamond, Ulf Andersson, Thomas R. Coleman, Christine N. Metz, Kevin J. Tracey, Sangeeta S. Chavan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The immune and nervous systems are two major organ systems responsible for host defense and memory. Both systems achieve memory and learning that can be retained, retrieved, and utilized for decades. Here, we report the surprising discovery that peri
Externí odkaz:
https://doaj.org/article/9c71b92f46bd42d5be41688497de3e7d
Autor:
Preetesh Jain, Mohammad Javdan, Franziska K. Feger, Pui Yan Chiu, Cristina Sison, Rajendra N. Damle, Tawfiqul A. Bhuiya, Filiz Sen, Lynne V. Abruzzo, Jan A. Burger, Andreas Rosenwald, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Nicholas Chiorazzi, Barbara Sherry
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
Background The levels and clinical relevance of Th17 cells and other interleukin-17-producing cells have not been analyzed in chronic lymphocytic leukemia. The objective of this study was to quantify blood and tissue levels of Th17 and other interleu
Externí odkaz:
https://doaj.org/article/255a3ce5dc8c48988504c3494e9ec965
Autor:
Gonzalo Blanco, Florencia Palacios, Kamala Vanarsa, Poojitha Dugyala, Pui Yan Chiu, Steven L Allen, Yasmine Kieso, Anna Puiggros, Jacqueline C. Barrientos, Xavier Calvo, Jonathan E. Kolitz, Eva Gimeno, Joanna M. Rhodes, Ana Ferrer, Kanti R Rai, Barbara Sherry, Blanca Espinet, Chandra Mohan, Nicholas Chiorazzi
Publikováno v:
Blood. 140:9859-9861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b43af6632a97f98a0776188a7883558
https://doi.org/10.1182/blood-2022-169722
https://doi.org/10.1182/blood-2022-169722