Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Barbara Seifert"'
Publikováno v:
Friess, F.; Roch, T.; Seifert, B.; Lendlein, A.; Wischke, C.: Phagocytosis of spherical and ellipsoidal micronetwork colloids from crosslinked poly(ε-caprolactone). In: International Journal of Pharmaceutics. Vol. 567 (2019) 118461. (DOI: /10.1016/j.ijpharm.2019.118461)
The effect of non-spherical particle shapes on cellular uptake has been reported as a general design parameter to control cellular recognition of particulate drug carriers. Beside shape, also size and cell-particle ratio should mutually effect phagoc
Autor:
Rumiana Tzoneva, V. Pehlivanova, Iana Tsoneva, Tino Becker, Andreas Lendlein, V. Krasteva, Karola Lützow, Klaus Richau, Barbara Seifert
Publikováno v:
Journal of Materials Research. 28:2180-2186
Tissue engineering principles suggest the formation of 3D scaffolds based on polymer fibers and adhesive proteins. These scaffolds aim to mimic the native extracellular matrix and thus providing a favorable environment for cell attachment and prolife
Publikováno v:
Tzoneva, R.; Seifert, B.; Behl, M.; Lendlein, A.: Elastic multiblock copolymers for vascular regeneration: Protein adsorption and hemocompatibility. In: Clinical Hemorheology and Microcirculation. Vol. 52 (2012) 2-4, 337-348. (DOI: 10.3233/CH-2012-1609)
Hemocompatibility of elastic multiblock copolymers PDC, based on poly(p-dioxanone) (PPDO)/poly(ε-caprolactone)-segments, capable of a shape-memory effect, and PDD, based on PPDO/poly((adipinate-alt-1,4-butanediol)-co-(adipinate-alt-ethylene glycol)-
Autor:
George Altankov, Thomas Weigel, Natalia Krasteva, Wolfgang Albrecht, Thomas Groth, Michael Schossig, Barbara Seifert
Publikováno v:
Biomaterials. 25:2467-2476
The effect of the porosity of acrylonitrile-N-vinylpyrrolidone copolymer membranes on human C3A hepatoblastoma cell adhesive interaction and functioning is investigated on four membranes with an average pore size ranging between 6 and 12 nm. Adhesion
Autor:
Thomas Groth, Yannis F. Missirlis, Wolfgang Albrecht, Barbara Seifert, Dieter Paul, G von Sengbusch, Klaus Richau, G. Mihanetzis
Publikováno v:
Artificial Organs. 26:189-199
Membranes for biohybrid organs such as the biohybrid liver support system have to face 2 different environments, namely blood and tissue cells. Accordingly, the respective membrane surfaces must have optimal properties in terms of biocompatibility fo
Publikováno v:
Clinical hemorheology and microcirculation. 52(2-4)
A dataset of 439 confocal laser scanning microscopic images was analyzed to investigate the potential of an image-based automated analysis for identifying and assessing adherent thrombocytes on polymer surfaces. Parameters for image optimization of g
Autor:
Andreas Lendlein, Marc Behl, Iana Tsoneva, Claudia Weckwerth, Barbara Seifert, Matthias Heuchel, Rumiana Tzoneva
Publikováno v:
Journal of biomaterials science. Polymer edition. 22(16)
There is a need to create cell- and histocompatible implant materials, which might temporarily replace the mechanical function of a native tissue for regenerative therapies. To match the elastic behavior of the native tissue two different multiblock
Autor:
Barbara Seifert, Karola Lützow, Maik Lange, Frank Klein, Bernhard Hiebl, Karl Kratz, Friedrich Jung, Andreas Lendlein, Thomas Weigel
Publikováno v:
Journal of biotechnology. 148(1)
Most polymers used in clinical applications today are materials that have been developed originally for application areas other than biomedicine. Testing the cell- and tissue-compatibility of novel materials in vitro and in vivo is of key importance
Autor:
Barbara Seifert, Guenter Malsch, Wolfgang Albrecht, George Altankov, Andreas Lendlein, Thomas Groth, Aneliya Kostadinova
Publikováno v:
Kostadinova, A.; Seifert, B.; Albrecht, W.; Malsch, G.; Groth, T.; Lendlein, A.; Altankov, G.: Novel Polymer Blends for the Preparation of Membranes for Biohybrid Liver Systems . In: Journal of Biomaterials Science-Polymer Edition. Vol. 20 (2009) 5-6, 821-839. (DOI: 10.1163/156856209X427005)
It was found previously that membranes based on co-polymers of acrylonitrile (AN) and 2-acrylamido-2-methyl-propansulfonic acid (AMPS) greatly stimulated the functionality and survival of primary hepatocytes. In those studies, however, the pure AN-AM
Autor:
Wolfgang Albrecht, Rumiana Tzoneva, Thomas Groth, Andreas Lendlein, Klaus Richau, Barbara Seifert
Publikováno v:
Tzoneva, R.; Seifert, B.; Albrecht, W.; Richau, K.; Lendlein, A.; Groth, T.: Poly(ether imide) membranes: studies on the effect of surface modification and protein pre-adsorption on endothelial cell adhesion, growth and function. In: Journal of Biomaterials Science-Polymer Edition. Vol. 19 (2008) 7, 837-852. (DOI: 10.1163/156856208784613523)
Poly(ether imide) (PEI) membranes of which the surface was modified with carboxylic groups were tested in comparison to pure PEI and poly(ethylene terephtalate) (PET) for their ability to support attachment, growth and function of human umbilical vei