Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Barbara Schreier"'
Autor:
Virginie Dubourg, Gerald Schwerdt, Barbara Schreier, Michael Kopf, Sigrid Mildenberger, Ralf A. Benndorf, Michael Gekle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Endothelial cells (EC) are key players in vascular function, homeostasis and inflammation. EC show substantial heterogeneity due to inter-individual variability (e.g. sex-differences) and intra-individual differences as they originate from d
Externí odkaz:
https://doaj.org/article/d85fe54df585415eadc3aa04dfbb82dd
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2241 (2023)
(1) Background: Obesity is associated with hypertension because of endocrine dysregulation of the adrenergic and the renin–angiotensin–aldosterone systems. The epidermal growth factor receptor (EGFR) is an important signaling hub in the cardiovas
Externí odkaz:
https://doaj.org/article/82ad53fb64e64b18bf61a75e7d832853
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Background Cardiovascular disease is the leading cause of death worldwide. Cardiac electrical remodeling including altered ion channel expression and imbalance of calcium homeostasis can have detrimental effects on cardiac function. While it
Externí odkaz:
https://doaj.org/article/78d3075246294c98ab957cbd4f148eb3
Autor:
Katharina Stroedecke, Sandra Meinel, Fritz Markwardt, Udo Kloeckner, Nicole Straetz, Katja Quarch, Barbara Schreier, Michael Kopf, Michael Gekle, Claudia Grossmann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The EGF receptor (EGFR) has been extensively studied in tumor biology and recently a role in cardiovascular pathophysiology was suggested. The mineralocorticoid receptor (MR) is an important effector of the renin–angiotensin–aldosterone-
Externí odkaz:
https://doaj.org/article/e7c08a9ce14145d4984ef05ebc288861
Autor:
Barbara Schreier, Christian Stern, Virginie Dubourg, Alexander Nolze, Sindy Rabe, Sigrid Mildenberger, Claudia Wickenhauser, Michael Gekle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Vascular EGF receptors (EGFR) influence function and structure of arterial vessels. In genetic mouse models we described the role of vascular smooth muscle (VSMC) EGFR for proper physiological function and structure as well as for pathophysi
Externí odkaz:
https://doaj.org/article/239465dc77464e889819e565945224a9
Autor:
Virginie Dubourg, Barbara Schreier, Gerald Schwerdt, Sindy Rabe, Ralf A. Benndorf, Michael Gekle
Publikováno v:
Cells, Vol 11, Iss 12, p 1936 (2022)
In vivo, cells are simultaneously exposed to multiple stimuli whose effects are difficult to distinguish. Therefore, they are often investigated in experimental cell culture conditions where stimuli are applied separately. However, it cannot be presu
Externí odkaz:
https://doaj.org/article/4edd169391d546f584bf698c7b4e6648
Autor:
Julia Hupfeld, Maximilian Ernst, Maria Knyrim, Stephanie Binas, Udo Kloeckner, Sindy Rabe, Katja Quarch, Danny Misiak, Matthew Fuszard, Claudia Grossmann, Michael Gekle, Barbara Schreier
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 719 (2021)
MicroRNAs (miRs) contribute to different aspects of cardiovascular pathology, among them cardiac hypertrophy and atrial fibrillation. Cardiac miR expression was analyzed in a mouse model with structural and electrical remodeling. Next-generation sequ
Externí odkaz:
https://doaj.org/article/5789de281c084aa7ac2f8d900502e997
Autor:
Sarah M. Grundmann, Alexandra Schutkowski, Barbara Schreier, Sindy Rabe, Bettina König, Michael Gekle, Gabriele I. Stangl
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Vitamin D is thought to play a role in blood pressure regulation, which in turn can influence cardiovascular risk. Several meta-analyses of cohort studies found low serum levels of 25-hydroxyvitamin D to be associated with increased blood pressure or
Externí odkaz:
https://doaj.org/article/dee6fa63b33a40a4aed8055cadd8ea22
Publikováno v:
Emerging Infectious Diseases, Vol 16, Iss 4, Pp - (2010)
Externí odkaz:
https://doaj.org/article/9cab32ef770749428abcfd9e65e1a34e
Autor:
Heike Braun, Michael Hauke, Robert Eckenstaler, Markus Petermann, Anne Ripperger, Niklas Kühn, Edzard Schwedhelm, Beatrice Ludwig-Kraus, Frank Bernhard Kraus, Virginie Dubourg, Alma Zernecke, Barbara Schreier, Michael Gekle, Ralf A. Benndorf
Publikováno v:
Free Radical Biology and Medicine. 185:36-45
The F2-isoprostane 8-iso-PGF2α (also known as 15-F2t-isoprostane, iPF2α-III, 8-epi PGF2α, 15(S)-8-iso-PGF2α, or 8-Isoprostane), a thromboxane A2 receptor (TP) agonist, stable biomarker of oxidative stress, and risk marker of cardiovascular diseas