Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Barbara Saccà"'
Autor:
Richard Kosinski, Ann Mukhortava, Wolfgang Pfeifer, Andrea Candelli, Philipp Rauch, Barbara Saccà
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Self-assembly of DNA origami is a complex folding problem without a unified view of the energetic factors involved. Here the authors analyse identical structures that differ by nucleotide sequence and identify how mechanical stress at nucleation site
Externí odkaz:
https://doaj.org/article/18c3fb80b55445e2b7a1c1e064f84fa5
Autor:
Rico Schieweck, Elisa-Charlott Schöneweiss, Max Harner, Daniela Rieger, Christin Illig, Barbara Saccà, Bastian Popper, Michael A. Kiebler
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8998 (2021)
RNA-binding proteins (RBPs) are essential regulators controlling both the cellular transcriptome and translatome. These processes enable cellular plasticity, an important prerequisite for growth. Cellular growth is a complex, tightly controlled proce
Externí odkaz:
https://doaj.org/article/eb5e55f424c740aaaaa93a4ab1fb08d7
Autor:
Andreas Sprengel, Pascal Lill, Pierre Stegemann, Kenny Bravo-Rodriguez, Elisa-C. Schöneweiß, Melisa Merdanovic, Daniel Gudnason, Mikayel Aznauryan, Lisa Gamrad, Stephan Barcikowski, Elsa Sanchez-Garcia, Victoria Birkedal, Christos Gatsogiannis, Michael Ehrmann, Barbara Saccà
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Current strategies for protein encapsulation in DNA vessels for controlled enzymatic catalysis or therapeutic delivery rely on formation of covalent complexes. Here, the authors design a system that mimics natural reversible non-covalent host–guest
Externí odkaz:
https://doaj.org/article/5226d94ebae64287be29caae8f6fe6be
Publikováno v:
Molecules, Vol 25, Iss 23, p 5466 (2020)
Since the pioneering work of Ned Seeman in the early 1980s, the use of the DNA molecule as a construction material experienced a rapid growth and led to the establishment of a new field of science, nowadays called structural DNA nanotechnology. Here,
Externí odkaz:
https://doaj.org/article/4cf43dd6a1c24e29b42490d0f9ae3cd2
Publikováno v:
Molecules, Vol 24, Iss 20, p 3694 (2019)
Nucleic acids and proteins are two major classes of biopolymers in living systems. Whereas nucleic acids are characterized by robust molecular recognition properties, essential for the reliable storage and transmission of the genetic information, the
Externí odkaz:
https://doaj.org/article/5492232df16c46dc85c319c217682656
Autor:
Richard Kosinski, Barbara Saccà
Publikováno v:
DNA Origami. :241-260
Autor:
Lena J. Stenke, Barbara Saccà
Publikováno v:
Bioconjugate chemistry.
Over the past 40 years, structural and dynamic DNA nanotechnologies have undoubtedly demonstrated to be effective means for organizing matter at the nanoscale and reconfiguring equilibrium structures, in a predictable fashion and with an accuracy of
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany).
Compartmentalization is the strategy evolved by nature to control reactions in space and time. The ability to emulate this strategy through synthetic compartmentalization systems has rapidly evolved in the past years, accompanied by an increasing und
Autor:
Richard Kosinski, Joel Mieres Perez, Elisa-C. Schöneweiß, Yasser B. Ruiz-Blanco, Irene Ponzo, Kenny Bravo-Rodriguez, Michael Erkelenz, Sebastian Schlücker, Guido Uhlenbrock, Elsa Sanchez-Garcia, Barbara Saccà
Publikováno v:
Science Advances
Description
DNA nanostructures invert the catalytic response of thrombin to substrates of opposite net charge.
DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still poorly u
DNA nanostructures invert the catalytic response of thrombin to substrates of opposite net charge.
DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still poorly u
Autor:
Sarah E. Ochmann, Barbara Saccà, Himanshu Joshi, Ulrich F. Keyser, Pierre Stegemann, Henri G. Franquelim, E. Bueber, Philip Tinnefeld, Aleksei Aksimentiev
Publikováno v:
Nano letters. 21(20)
Signal transmission in neurons goes along with changes in the transmembrane potential. To report them, different approaches including optical voltage-sensing dyes and genetically encoded voltage indicators have evolved. Here, we present a DNA nanotec