Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Barbara S. Skinner"'
Autor:
Andrew Burchat, Michael M. Friedman, David J. Calderwood, Barbara S. Skinner, Kurt Ritter, Gavin C. Hirst, Biqin Li, Paul Rafferty
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:1687-1690
A series of para-substituted 3-phenyl pyrazolopyrimidines was synthesized and evaluated as inhibitors of lck. The nature of the substitution affected enzyme selectivity and potency for lck, src, kdr, and tie-2. The para-phenoxyphenyl analogue 2 is an
Autor:
Andrew Burchat, Barbara S. Skinner, Gavin C. Hirst, Biqin Li, Paul Rafferty, David J. Calderwood, Michael M. Friedman, Kurt Ritter
Publikováno v:
ChemInform. 33
A series of para-substituted 3-phenyl pyrazolopyrimidines was synthesized and evaluated as inhibitors of lck. The nature of the substitution affected enzyme selectivity and potency for lck, src, kdr, and tie-2. The para-phenoxyphenyl analogue 2 is an