Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Barbara S. Sendtner"'
Autor:
Christiane D. Much, Barbara S. Sendtner, Konrad Schwefel, Eric Freund, Sander Bekeschus, Oliver Otto, Axel Pagenstecher, Ute Felbor, Matthias Rath, Stefanie Spiegler
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Cerebral cavernous malformations are slow-flow thrombi-containing vessels induced by two-step inactivation of the CCM1, CCM2 or CCM3 gene within endothelial cells. They predispose to intracerebral bleedings and focal neurological deficits. Our unders
Externí odkaz:
https://doaj.org/article/6235fddf84474db1b2750edac3925c4f
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
Abstract Background The CRISPR/Cas9 system has opened new perspectives to study the molecular basis of cerebral cavernous malformations (CCMs) in personalized disease models. However, precise genome editing in endothelial and other hard‐to‐transf
Externí odkaz:
https://doaj.org/article/e4129c3e1bc240e19044df029e923c5f
Autor:
Oliver Otto, Matthias Rath, Stefanie Spiegler, Ute Felbor, Axel Pagenstecher, Sander Bekeschus, Konrad Schwefel, Christiane D. Much, Eric Freund, Barbara S. Sendtner
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Cerebral cavernous malformations are slow-flow thrombi-containing vessels induced by two-step inactivation of the CCM1, CCM2 or CCM3 gene within endothelial cells. They predispose to intracerebral bleedings and focal neurological deficits. Our unders