Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions

Autor: Josephine Herz, Raluca Reitmeir, Sabine I. Hagen, Barbara S. Reinboth, Zeyun Guo, Anil Zechariah, Ayman ElAli, Thorsten R. Doeppner, Marco Bacigaluppi, Stefano Pluchino, Ülkan Kilic, Ertugrul Kilic, Dirk M. Hermann

Publikováno v: Neurobiology of Disease, Vol 45, Iss 3, Pp 1077-1085 (2012)

Vascular endothelial growth factor (VEGF) has potent angiogenic and neuroprotective effects in the ischemic brain. Its effect on axonal plasticity and neurological recovery in the post-acute stroke phase was unknown. Using behavioral tests combined w

Externí odkaz: https://doaj.org/article/d4062f5ecf414633a83b959ae6668ad9

Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia

Autor: Ursula Felderhoff-Müser, Wiebke Hansen, Ivo Bendix, Josephine Herz, Marco Sifringer, Katharina Lumpe, Karina Kempe, Ralf Herrmann, Martin Hadamitzky, Xinlin Hou, Yohan van de Looij, Meray Serdar, Stéphane Sizonenko, Barbara S. Reinboth, Rolf Heumann

Publikováno v: Brain, behavior, and immunity, Vol. 52 (2016) pp. 106-19

Cerebral white matter injury is a leading cause of adverse neurodevelopmental outcome in prematurely born infants involving cognitive deficits in later life. Despite increasing knowledge about the pathophysiology of perinatal brain injury, therapeuti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107efda10ac14301a02fe7283fc9f3ef
https://www.ncbi.nlm.nih.gov/pubmed/26456693

Erratum to: Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain

Autor: Raluca Reitmeir, Ertugrul Kilic, Barbara S. Reinboth, Zeyun Guo, Ayman ElAli, Anil Zechariah, Ülkan Kilic, Dirk M. Hermann

Publikováno v: Reitmeir, Raluca; Kilic, Ertugrul; Reinboth, Barbara S; Guo, Zeyun; ElAli, Ayman; Zechariah, Anil; Kilic, Ülkan; Hermann, Dirk M (2015). Erratum to: Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta neuropathologica, 130(4), p. 603. Springer 10.1007/s00401-015-1472-6

Erratum to: Acta Neuropathol (2012) 123:273–284. DOI 10.1007/s00401‑011‑0914‑z. The authors would like to correct Fig. 3 of the original manuscript, since the image in Fig. 3b does not correspond to a VEGF treated animal. Corrected Fig. 3 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae52dd962ce09e301fe7f07423159f1

Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain

Autor: Ulkan Kilic, Barbara S. Reinboth, Dirk M. Hermann, Ayman ElAli, Ertugrul Kilic, Anil Zechariah, Raluca Reitmeir, Zeyun Guo

Publikováno v: Reitmeir, Raluca; Kilic, Ertugrul; Reinboth, Barbara S; Guo, Zeyun; ElAli, Ayman; Zechariah, Anil; Kilic, Ulkan; Hermann, Dirk M (2012). Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta neuropathologica, 123(2), pp. 273-284. Berlin: Springer 10.1007/s00401-011-0914-z

Vascular endothelial growth factor (VEGF) is a potent angiogenic factor, which also has neuroprotective activity. In view of these dual actions on vessels and neurons, we were interested whether VEGF promotes long distance axonal plasticity in the is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05757be7d47211c0f2392d40d22c9506
https://boris.unibe.ch/15826/1/Reitmeir2012_Article_VascularEndothelialGrowthFacto.pdf

Endogenous hypothermic response to hypoxia reduces brain injury: Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal mice

Autor: Ivo Bendix, Hanna Abberger, Ursula Felderhoff-Müser, Sebastian Prager, Christian Köster, Barbara S. Reinboth, Josephine Herz

Publikováno v: Experimental Neurology. :264-275

Hypothermia treatment (HT) is the only formally endorsed treatment recommended for hypoxic-ischemic encephalopathy (HIE). However, its success in protecting against brain injury is limited with a number to treat of 7-8. The identification of the targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f867a6e2e7475f3106cba5f57966641