Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Barbara S, Sixt"'
Autor:
Robert J Bastidas, Mateusz Kędzior, Robert K Davidson, Stephen C Walsh, Lee Dolat, Barbara S Sixt, Jonathan N Pruneda, Jörn Coers, Raphael H Valdivia
Publikováno v:
eLife, Vol 12 (2024)
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen Chlamydia
Externí odkaz:
https://doaj.org/article/426a261476c445ab9709280aa9a9f586
Autor:
Karsten Meier, Lana H. Jachmann, Gözde Türköz, Mohammed Rizwan Babu Sait, Lucía Pérez, Oliver Kepp, Raphael H. Valdivia, Guido Kroemer, Barbara S. Sixt
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT The obligate intracellular bacterium Chlamydia trachomatis inserts a family of inclusion membrane (Inc) proteins into the membrane of its vacuole (the inclusion). The Inc CpoS is a critical suppressor of host cellular immune surveillance, bu
Externí odkaz:
https://doaj.org/article/c174e539b37e4bccb7df8b1155ca3c90
Autor:
Magnus Ölander, Barbara S Sixt
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010669 (2022)
Externí odkaz:
https://doaj.org/article/9b1d719ac11b42d1b4cf053c7230f5c7
Publikováno v:
Microbial Cell, Vol 4, Iss 3, Pp 101-104 (2017)
Bacteria of the phylum Chlamydiae infect a diverse range of eukaryotic host species, including vertebrate animals, invertebrates, and even protozoa. Characteristics shared by all Chlamydiae include their obligate intracellular lifestyle and a biphasi
Externí odkaz:
https://doaj.org/article/a13a01e027c14fe2aad102d0abc69493
Autor:
Kimberly Filcek, Katarina Vielfort, Samada Muraleedharan, Johan Henriksson, Raphael H Valdivia, Patrik M Bavoil, Barbara S Sixt
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224324 (2019)
The ability to introduce targeted genetic modifications in microbial genomes has revolutionized our ability to study the role and mode of action of individual bacterial virulence factors. Although the fastidious lifestyle of obligate intracellular ba
Externí odkaz:
https://doaj.org/article/df060dce5b814f3199d5fa99bacf57c2
Autor:
Robert J. Bastidas, Mateusz Kędzior, Lee Dolat, Barbara S. Sixt, Jonathan N. Pruneda, Raphael H. Valdivia
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Bacterial pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0636a3ffe7ff80f6ccc2e4cc48006bf0
https://doi.org/10.7554/elife.87386
https://doi.org/10.7554/elife.87386
Autor:
Barbara S. Sixt
Publikováno v:
Cell hostmicrobe. 30(4)
5 years ago, my colleagues and I revealed the Chlamydia trachomatis virulence factor CpoS as a suppressor of host cell-autonomous immunity. Here, I reflect on the events that inspired and enabled this research and place our discoveries in context to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3523b0847b30f08457e11dd9db2eea3
https://pubmed.ncbi.nlm.nih.gov/35421347
https://pubmed.ncbi.nlm.nih.gov/35421347
Autor:
Karsten Meier, Lana H. Jachmann, Lucía Pérez, Oliver Kepp, Raphael H. Valdivia, Guido Kroemer, Barbara S. Sixt
The obligate intracellular bacterium Chlamydia trachomatis inserts into the membrane of its vacuole (the inclusion) a family of poorly characterized Inc proteins. While the Inc CpoS was recently revealed as a critical suppressor of host cellular immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200f03c61a46a99bfa9efe445ee08b58
https://doi.org/10.1101/2022.02.18.481055
https://doi.org/10.1101/2022.02.18.481055
Autor:
Barbara S. Sixt
Publikováno v:
FEMS Microbiology Reviews
The phylum Chlamydiae constitutes a group of obligate intracellular bacteria that infect a remarkably diverse range of host species. Some representatives are significant pathogens of clinical or veterinary importance. For instance, Chlamydia trachoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814ff78afd6493ebc75c19eead76aec2
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181820
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181820
Autor:
Barbara S Sixt, Alexander Siegl, Constanze Müller, Margarete Watzka, Anna Wultsch, Dimitrios Tziotis, Jacqueline Montanaro, Andreas Richter, Philippe Schmitt-Kopplin, Matthias Horn
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003553 (2013)
The Chlamydiae are a highly successful group of obligate intracellular bacteria, whose members are remarkably diverse, ranging from major pathogens of humans and animals to symbionts of ubiquitous protozoa. While their infective developmental stage,
Externí odkaz:
https://doaj.org/article/413e6d8ffc4b4cbe84d2a40023d02624