Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Barbara Roniker"'
Autor:
Yuen-lung L. Sing, John A. Delyani, Dwain S. Tolbert, Chyung S. Cook, Brian Whelihan, Barbara Roniker, Stuart Levin, Diane Workman, Ricardo Rocha
Publikováno v:
Cardiovascular Drug Reviews. 19:185-200
Aldosterone, the final product of the renin-angiotensin-aldosterone system (RAAS), is a mineralocorticoid hormone that classically acts, via the mineralocorticoid (aldosterone) receptor, on epithelia of the kidneys, colon, and sweat glands to maintai
Autor:
Jeffrey L. Patrick, Scott Krause, Robert C. Davidson, Myron H. Weinberger, Thomas M. MacDonald, Barbara Roniker, William B. White, Luis M. Ruilope
Publikováno v:
American Heart Journal. 150:426-433
Background Sodium retention and volume expansion, mediated in part by aldosterone, are prominent features in low-renin hypertension. Agents that block aldosterone at its receptor sites, therefore, should have significant clinical benefit in patients
Autor:
Gordon H. Williams, Barbara Roniker, Joanna Niegowska, Luis M. Ruilope, Mark S Kipnes, Ellen Burgess, Jeffrey L. Patrick, R. Kolloch, Scott Krause
Publikováno v:
The American Journal of Cardiology. 93:990-996
This study compared the efficacy and tolerability of eplerenone and enalapril in 499 patients with stage 1 or 2 hypertension who were randomized to receive eplerenone or enalapril for 6 months in a 3-step titration-to-effect study. After 6 months, pa
Publikováno v:
The Journal of Clinical Pharmacology. 43:1203-1210
Since neither angiotensin-converting enzyme inhibitors (ACE-I) nor angiotensin II receptor blockers (ARB) can completely suppress aldosterone levels, there is a need for alternative/supplementary antihypertensive medications, such as the selective al
Autor:
Janice Kuse-Hamilton, Scott Krause, Barbara Roniker, Richard St Hillaire, William B. White, Michael A. Weber, Daniel Duprez
Publikováno v:
Hypertension. 41:1021-1026
Eplerenone is a highly selective aldosterone blocker, which is under development for the treatment of hypertension and heart failure. To assess its usefulness in older patients with systolic hypertension and widened pulse pressure, we compared the ef
Publikováno v:
American Journal of Hypertension. 15:709-716
Eplerenone, a selective aldosterone blocker (SAB) that is highly specific for the aldosterone receptor, has the potential to be efficacious in the treatment of hypertension.This 8-week, multicenter, double-blind, placebo-controlled trial assessed the
Autor:
Jose Lopez-Sendon, Dan Burns, Richard Bittman, Faiez Zannad, Barbara Roniker, Bertram Pitt, Felipe Martinez, Gordon H. Williams, James D. Neaton, Willem Remme, Jay H. Kleiman, Steve Hurley
Publikováno v:
Cardiovascular Drugs and Therapy. 15:79-87
Autor:
Robert S. Stern, T Daniel Fakouhi, Barbara Roniker, Nicholas J. Lowe, Teresa Bourget, Edward Allen Swabb
Publikováno v:
Clinical Pharmacology and Therapeutics. 56:587-591
Quinolone antimicrobials absorb ultraviolet radiation and, with appropriate drug concentrations, may cause photoreactions. Photoreactions have been reported for several quinolones, including lomefloxacin, a difluorinated quinolone antimicrobial. This
Autor:
Luis M. Ruilope-Urioste, Scott Krause, Jay H. Kleiman, Yves Lacourcière, Barbara Roniker, Ellen Burgess, Clement J. Maurath, Suzanne Oparil
Publikováno v:
Clinical therapeutics. 25(9)
Even within the normal range, aldosterone levels are linked to end-organ toxicity and mortality in patients with hypertension. Treatment with angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers does not sufficiently reduce plasm
Autor:
Roland Willenbrock, Jay Kleiman, Faiez Zannad, Robert A. Phillips, Gordon H. Williams, Barbara Roniker, Nathaniel Reichek, Bertram Pitt, Scott Krause, Daniel Burns
Publikováno v:
Circulation. 108(15)
Background— Elevated renin-angiotensin-aldosterone system activity correlates with left ventricular hypertrophy (LVH) and cardiovascular risk, but the relative contributions of angiotensin II and aldosterone remain unclear. This study compared LVH