Výsledky vyhledávání - "Barbara Roig"

The discoidin domain receptor 1 gene has a functional A2RE sequence

Autor: Barbara, Roig, Sílvia, Moyano, Lourdes, Martorell, Javier, Costas, Elisabet, Vilella

Publikováno v: Journal of neurochemistry. 120(3)

Discoidin domain receptor 1 (DDR1) is expressed in myelin oligodendrocytes and co-localizes with myelin basic protein (MBP). Alternative splicing of DDR1 generates five isoforms designated DDR1a-e. The MBP mRNA contains an hnRNP A2 response element (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbc316a31b7656c99437c113824f7d9f
https://pubmed.ncbi.nlm.nih.gov/22077590

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Assessment of nucleotide excision repair XPD polymorphisms in the peripheral blood of gemcitabine/cisplatin-treated advanced non-small-cell lung cancer patients

Autor: Barbara Roig, Miguel Taron, Jose Javier Sanchez, Carlos Camps, Cristina Queralt, Natividad Martínez, Carmen Sarries, Rafael Rosell, Eva Sancho

Publikováno v: Clinical lung cancer. 4(4)

Only about one third of non—small-cell lung cancer (NSCLC) patients respond to cisplatin-based chemotherapy. Cisplatin DNA adducts are commonly repaired through the nucleotide excision repair pathway. The study of rare inherited disorders such as x

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0496849fb49bffdba92c06320fccd77
https://pubmed.ncbi.nlm.nih.gov/14624713

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Methylation patterns and K-ras mutations in tumor and paired serum of resected non-small-cell lung cancer patients

Autor: Miquel Taron, Mireia Margeli, Rafael Rosell, Carme Sarries, Barbara Roig, Jose Miguel Sanchez, Jose Luis Ramirez, Itziar de Aguirre, Cristina Queralt, Julio Astudillo, Jose Luis Manzano, Jose Javier Sanchez, Pedro López de Castro, Daniel Escuin

Publikováno v: Cancer letters. 193(2)

Gene methylation and K-ras mutations were examined in tumor and paired serum DNA of 50 resected non-small-cell lung cancer patients. RASSF1A, death associated protein kinase and target of methylation-induced silencing were methylated in 17/50 (34%),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b430f25f25079a93d5e1bb78031e6879
https://pubmed.ncbi.nlm.nih.gov/14744528

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Nucleotide excision repair pathways involved in cisplatin resistance in non-small-cell lung cancer

Autor: Agustí Barnadas, Rafael Rosell, Carme Sarries, Miquel Taron, Barbara Roig, Giorgio V. Scagliotti

In spite of the growing list of genetic abnormalities identified as being involved in DNA repair pathways that alter chemosensitivity in non-small-cell lung cancer (NSCLC) patients, translational assays have not yet been developed for use in individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5adba77b95edfc5ff219d52d0a377b
http://hdl.handle.net/2318/1691276

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Pharmacogenomic strategies for developing customized chemotherapy in non-small cell lung cancer

Autor: Albert Abad, Rafael Rosell, Carme Sarries, Barbara Roig, Miquel Taron, Eric B. Haura, Giorgio V. Scagliotti

Publikováno v: Pharmacogenomics. 3(6)

We deal with six groups of cytotoxic drugs commonly used in the treatment of non-small cell lung cancer (NSCLC). Although there are many reviews of thymidylate synthase (TS) and antifolate inhibitors, in this article, we have tried to highlight aspec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900b3bed344c0cfc3a2e12a71c632f57
https://pubmed.ncbi.nlm.nih.gov/12437479

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β-Tubulin mutational analysis: tantalizing findings

Autor: Cristina Queralt, Barbara Roig, Rafael Rosell, Carme Sarries, Miquel Taron

Publikováno v: Lung Cancer. 38:99-100

Resistance to taxanes could be due to alterations in the intracellular target, tubulin. Such alterations can include decreased tubulin, point mutations, altered expression of b-tubulin isotypes and acetylation of atubulin. Acquired b-tubulin mutation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452d4c94ddefce5eab8280c30d4eb499
https://doi.org/10.1016/s0169-5002(02)00188-5

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