Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Barbara Ranscht"'
Autor:
Taka-aki Sakaue, Yuya Fujishima, Yoko Fukushima, Yuri Tsugawa-Shimizu, Shiro Fukuda, Shunbun Kita, Hitoshi Nishizawa, Barbara Ranscht, Kohji Nishida, Norikazu Maeda, Iichiro Shimomura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Adiponectin (APN), a protein abundantly secreted from adipocytes, has been reported to possess beneficial effects on cardiovascular diseases in association with its accumulation on target organs and cells by binding to T-cadherin. However, l
Externí odkaz:
https://doaj.org/article/b84f0b3047784279a16719e447e62d57
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The destruction of the myelin sheath that encircles axons leads to impairments of nerve conduction and neuronal dysfunctions. A major demyelinating disorder is multiple sclerosis (MS), a progressively disabling disease in which immune cells attack th
Externí odkaz:
https://doaj.org/article/6a0412df19c04beaa013b7cebb436796
Autor:
Marisol Veny, Daniela Grases, Karolina Kucharova, Wai Wai Lin, Jennifer Nguyen, Sarah Huang, Carl F. Ware, Barbara Ranscht, John R. Šedý
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuronal regulation of diverse physiological functions requires complex molecular interactions in innervated tissues to maintain proper organ function. Here we show that loss of the neuronal cell surface adhesion/recognition molecule Contactin-1 (Cnt
Externí odkaz:
https://doaj.org/article/a3263a6849d8466c87b739466b599d4d
Autor:
Jana Drgonova, Donna Walther, G. Luke Hartstein, Mohammad O. Bukhari, Michael H. Baumann, Jonathan Katz, F. Scott Hall, Elizabeth R. Arnold, Shaun Flax, Anthony Riley, Olga Rivero, Klaus-Peter Lesch, Juan Troncoso, Barbara Ranscht, George R. Uhl
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 537-547 (2016)
Abstract The Cadherin 13 (CDH13) gene encodes a cell adhesion molecule likely to influence development and connections of brain circuits that modulate addiction, locomotion and cognition, including those that involve midbrain dopamine neurons. Human
Externí odkaz:
https://doaj.org/article/f5a73434f62e4c7da5554e4adfb91325
Autor:
Aman P. Mann, Pablo Scodeller, Sazid Hussain, Jinmyoung Joo, Ester Kwon, Gary B. Braun, Tarmo Mölder, Zhi-Gang She, Venkata Ramana Kotamraju, Barbara Ranscht, Stan Krajewski, Tambet Teesalu, Sangeeta Bhatia, Michael J. Sailor, Erkki Ruoslahti
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Accurate treatment of traumatic brain injuries, a leading cause of neurological disability and death in young people, is hampered by poor accumulation of drugs in the brain. Here, the authors describe a tetrapeptide that can efficiently target brain
Externí odkaz:
https://doaj.org/article/9ba4b22334aa479f9406152857335901
Autor:
Lisette M. Acevedo, Jeffrey N. Lindquist, Breda M. Walsh, Peik Sia, Flavio Cimadamore, Connie Chen, Martin Denzel, Cameron D. Pernia, Barbara Ranscht, Alexey Terskikh, Evan Y. Snyder, David A. Cheresh
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1075-1088 (2015)
To gain insight into the cellular and molecular cues that promote neurovascular co-patterning at the earliest stages of human embryogenesis, we developed a human embryonic stem cell model to mimic the developing epiblast. Contact of ectoderm-derived
Externí odkaz:
https://doaj.org/article/06246247775f42d7b312dc2b3d07c835
Autor:
David I Kasahara, Alison S Williams, Leandro A Benedito, Barbara Ranscht, Lester Kobzik, Christopher Hug, Stephanie A Shore
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65829 (2013)
Adiponectin, an adipose derived hormone with pleiotropic functions, binds to several proteins, including T-cadherin. We have previously reported that adiponectin deficient (Adipo(-/-)) mice have increased IL-17A-dependent neutrophil accumulation in t
Externí odkaz:
https://doaj.org/article/670afc39aa1445eeb8add390567d3314
Autor:
Alison S Williams, David I Kasahara, Norah G Verbout, Alexey V Fedulov, Ming Zhu, Huiqing Si, Allison P Wurmbrand, Christopher Hug, Barbara Ranscht, Stephanie A Shore
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41088 (2012)
Adiponectin is an adipose derived hormone that declines in obesity. We have previously shown that exogenous administration of adiponectin reduces allergic airways responses in mice. T-cadherin (T-cad; Cdh13) is a binding protein for the high molecula
Externí odkaz:
https://doaj.org/article/9f2430ecc1524d4bae9b339bbf49f753
Autor:
Barbara Ranscht, Robert D. Cardiff, Lawrence Shapiro, Gregory Shostak, Lionel W. Hebbard, Martin S. Denzel
Supplementary Data from Adiponectin Deficiency Limits Tumor Vascularization in the MMTV-PyV-mT Mouse Model of Mammary Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02257586e9823b243aea980b7eae03b4
https://doi.org/10.1158/1078-0432.22439314
https://doi.org/10.1158/1078-0432.22439314
Autor:
Barbara Ranscht, Robert D. Cardiff, Lawrence Shapiro, Gregory Shostak, Lionel W. Hebbard, Martin S. Denzel
Purpose: High levels of the fat-secreted cytokine adiponectin (APN) are present in the circulation of healthy people, whereas low levels correlate with an increased incidence of breast cancer in women. The current study experimentally probes the phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfc7653cbff85df556ea0edc66c21ab
https://doi.org/10.1158/1078-0432.c.6516802.v1
https://doi.org/10.1158/1078-0432.c.6516802.v1