Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Barbara Rakitsch"'
Publikováno v:
Journal of Mathematics in Industry, Vol 14, Iss 1, Pp 1-36 (2024)
Abstract Design patterns provide a systematic way to convey solutions to recurring modeling challenges. This paper introduces design patterns for hybrid modeling, an approach that combines modeling based on first principles with data-driven modeling
Externí odkaz:
https://doaj.org/article/803faca22cfe4632b32642a5b2e9b77c
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006693 (2017)
Joint genetic models for multiple traits have helped to enhance association analyses. Most existing multi-trait models have been designed to increase power for detecting associations, whereas the analysis of interactions has received considerably les
Externí odkaz:
https://doaj.org/article/0ab3dd7d328a46a2b2b3b1d23f4a799f
Publikováno v:
IEEE transactions on pattern analysis and machine intelligence.
Neural Stochastic Differential Equations (NSDEs) model the drift and diffusion functions of a stochastic process as neural networks. While NSDEs are known to make accurate predictions, their uncertainty quantification properties have been remained un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb567e42e70d53717cc4b1492d74da9a
https://pubmed.ncbi.nlm.nih.gov/36037461
https://pubmed.ncbi.nlm.nih.gov/36037461
Publikováno v:
University of Southern Denmark
Gaussian Process state-space models capture complex temporal dependencies in a principled manner by placing a Gaussian Process prior on the transition function. These models have a natural interpretation as discretized stochastic differential equatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc452d6dfb22c913b8b696a5e3b2db7c
http://arxiv.org/abs/2112.03230
http://arxiv.org/abs/2112.03230
Publikováno v:
University of Southern Denmark
Neural Stochastic Differential Equations model a dynamical environment with neural nets assigned to their drift and diffusion terms. The high expressive power of their nonlinearity comes at the expense of instability in the identification of the larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12ec1ce73b522de6e1d4277fe64957e
http://arxiv.org/abs/2006.09914
http://arxiv.org/abs/2006.09914
Publikováno v:
Nature Methods. 12:755-758
Set tests are a powerful approach for genome-wide association testing between groups of genetic variants and quantitative traits. We describe mtSet (http://github.com/PMBio/limix), a mixed-model approach that enables joint analysis across multiple co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c46c9cb73b9c33ca9832f8dbe203d2
https://doi.org/10.1038/nmeth.3439
https://doi.org/10.1038/nmeth.3439
Autor:
Dominik G. Grimm, Carmen Martín Pizarro, Karsten M. Borgwardt, François Vasseur, Eunyoung Chae, Anette Habring-Müller, Detlef Weigel, Daniel Koenig, Danelle K. Seymour, Barbara Rakitsch
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 46
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Significance Hybrid progeny of inbred parents are often more fit than their parents. Such hybrid vigor, or heterosis, is the focus of many plant breeding programs, and the rewards are evident. Hybrid maize has for many decades accounted for the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14c25f5f10c30c9140168daacff41b8
https://escholarship.org/uc/item/4xr1p4hk
https://escholarship.org/uc/item/4xr1p4hk
Autor:
Benjamin M. Neale, Jacqueline I. Goldstein, Hailiang Huang, Gina M. Peloso, Mark J. Daly, Carl-Johann Simon-Gabriel, Barbara Rakitsch, Daniel P. Howrigan, Karsten M. Borgwardt
Recent advances in genotyping and sequencing technologies have made detecting rare variants in large cohorts possible. Various analytic methods for associating disease to rare variants have been proposed, including burden tests, C-alpha and SKAT. Mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b205cbfcf6a8727a2f0511395348e98d
Autor:
Katy Morgan, Barbara Rakitsch, Mark Leaver, Karsten M. Borgwardt, Christian Rödelsperger, Ralf J. Sommer, Jan M. Meyer, Vahan Serobyan, Dominik G. Grimm, Angela McGaughran, Eduardo Moreno
Publikováno v:
Molecular Biology and Evolution
Understanding how new species form requires investigation of evolutionary forces that cause phenotypic and genotypic changes among populations. However, the mechanisms underlying speciation vary and little is known about whether genomes diversify in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9a53dfd3aa1aec981d7df122e2a0be
https://hdl.handle.net/21.11116/0000-000C-F2A2-B
https://hdl.handle.net/21.11116/0000-000C-F2A2-B
Autor:
Norbert Hilf, Barbara Rakitsch, Helen Hörzer, Arun Satelli, Franziska Hoffgaard, Oliver Schoor, Harpreet Singh-Jasuja, Weinschenk Toni, Jens Fritsche
Publikováno v:
Cancer Research. 78:662-662
Adoptive cellular therapy (ACT) has dramatically changed the landscape of cancer immunotherapy. ACTolog® and ACTengine® are actively personalized ACT approaches employing T-cell receptor products based on a warehouse of human leucocyte antigen (HLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d16c4cebf791b90f55a25513c69f285
https://doi.org/10.1158/1538-7445.am2018-662
https://doi.org/10.1158/1538-7445.am2018-662