Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Barbara R. Tschida"'
Autor:
Caitlin B. Conboy, Germán L. Vélez‐Reyes, Barbara R. Tschida, Hsiangyu Hu, Gabriel Kaufmann, Nicholas Koes, Bryant Keller, Clara Alsinet, Helena Cornellà, Roser Pinyol, Juan E. Abrahante, Nuri A. Temiz, Michael A. Linden, Khalid Amin, Timothy P. Kuka, Vincent W. Keng, Josep M. Llovet, Timothy K. Starr, David A. Largaespada
Publikováno v:
Hepatology Communications, Vol 3, Iss 11, Pp 1496-1509 (2019)
Each year, more than 25,000 people succumb to liver cancer in the United States, and this neoplasm represents the second cause of cancer‐related death globally. R‐spondins (RSPOs) are secreted regulators of Wnt signaling that function in developm
Externí odkaz:
https://doaj.org/article/0eab1ccaa58a47a08d90c0ba26613dba
Autor:
Jeffrey C. To, Amy P. Chiu, Barbara R. Tschida, Lilian H. Lo, Cynthia H. Chiu, Xiao-Xiao Li, Timothy P. Kuka, Michael A. Linden, Khalid Amin, Wing-Cheung Chan, Jason B. Bell, Branden S. Moriarity, David A. Largaespada, Vincent W. Keng
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100223- (2021)
Background & Aims: Zinc finger and BTB domain containing 20 (ZBTB20) has been implicated as a potential oncogene in liver cancer. However, knockout studies have shown it to be a transcriptional repressor of the alpha-foetoprotein (Afp) gene in adult
Externí odkaz:
https://doaj.org/article/58dd8d290ff94e908089e3e2954c131c
Autor:
Jianqiang Wu, Vincent W. Keng, Deanna M. Patmore, Jed J. Kendall, Ami V. Patel, Edwin Jousma, Walter J. Jessen, Kwangmin Choi, Barbara R. Tschida, Kevin A.T. Silverstein, Danhua Fan, Eric B. Schwartz, James R. Fuchs, Yuanshu Zou, Mi-Ok Kim, Eva Dombi, David E. Levy, Gang Huang, Jose A. Cancelas, Anat O. Stemmer-Rachamimov, Robert J. Spinner, David A. Largaespada, Nancy Ratner
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1979-1990 (2016)
To identify genes and signaling pathways that initiate Neurofibromatosis type 1 (NF1) neurofibromas, we used unbiased insertional mutagenesis screening, mouse models, and molecular analyses. We mapped an Nf1-Stat3-Arid1b/β-catenin pathway that becom
Externí odkaz:
https://doaj.org/article/b85859bc4dea43bd98344313076ad5bb
Autor:
Vincent W. Keng, Adrienne L. Watson, Eric P. Rahrmann, Hua Li, Barbara R. Tschida, Branden S. Moriarity, Kwangmin Choi, Tilat A. Rizvi, Margaret H. Collins, Margaret R. Wallace, Nancy Ratner, David A. Largaespada
Publikováno v:
Sarcoma, Vol 2012 (2012)
The genetic mechanisms involved in the transformation from a benign neurofibroma to a malignant sarcoma in patients with neurofibromatosis-type-1- (NF1-)associated or sporadic malignant peripheral nerve sheath tumors (MPNSTs) remain unclear. It is hy
Externí odkaz:
https://doaj.org/article/47da9adc73ef4a64bea05365ec9576c1
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary Figure S4. Serum metabolite profiles of experimental animals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24958c300980b21687e820e88e37876d
https://doi.org/10.1158/1541-7786.22516128
https://doi.org/10.1158/1541-7786.22516128
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Chronic hepatitis B viral (HBV) infection remains a high underlying cause for hepatocellular carcinoma (HCC) worldwide, while the genetic mechanisms behind this remain unclear. This study elucidated the mechanisms contributing to tumor development in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fc2b46122901b041db9bc0b9d8eb88
https://doi.org/10.1158/1541-7786.c.6541287
https://doi.org/10.1158/1541-7786.c.6541287
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary materials and methods for PCR and serum preparation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a5bd4d0aaaa7236c30697665b61ba3
https://doi.org/10.1158/1541-7786.22516116
https://doi.org/10.1158/1541-7786.22516116
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary Table S3. Up-stream regulator of IGF2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5638d21bde6004e9e8de9c4b122b36cb
https://doi.org/10.1158/1541-7786.22516119.v1
https://doi.org/10.1158/1541-7786.22516119.v1
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNET) are aggressive, poorly differentiated brain tumors with limited effective therapies. Using Sleeping Beauty (SB) transposon mutagenesis, we identified novel genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcfc7720d1848ea19440c3e7a8f431f
https://doi.org/10.1158/0008-5472.c.6511413.v1
https://doi.org/10.1158/0008-5472.c.6511413.v1
Autor:
David A. Largaespada, Vincent W. Keng, Adam J. Dupuy, Joseph H. Nadeau, Lewis R. Roberts, Ju Dong Yang, Aaron L. Sarver, Rachel A. Heuer, Pauline J. Beckmann, Khalid Amin, Michael A. Linden, Wendy A. Hudson, Sandra Wagner, Robert Hullsiek, Carlos A. Tierrablanca, Jesse D. Riordan, Lindsey A. Lee, Timothy P. Kuka, Nuri A. Temiz, Barbara R. Tschida
Oncoprints showing steatosis-associated CIS gene amplifications, deep deletions, and mutations occurring in at least 5% of all(S5), steatosis-associated(S6), and alcohol-associated(S7) TCGA HCC cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454cd20e521cb04dc3547458aa1f7623
https://doi.org/10.1158/0008-5472.22415118
https://doi.org/10.1158/0008-5472.22415118