Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Barbara R Tschida"'
Autor:
Jesse D Riordan, Vincent W Keng, Barbara R Tschida, Todd E Scheetz, Jason B Bell, Kelly M Podetz-Pedersen, Catherine D Moser, Neal G Copeland, Nancy A Jenkins, Lewis R Roberts, David A Largaespada, Adam J Dupuy
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003441 (2013)
We previously utilized a Sleeping Beauty (SB) transposon mutagenesis screen to discover novel drivers of HCC. This approach identified recurrent mutations within the Dlk1-Dio3 imprinted domain, indicating that alteration of one or more elements withi
Externí odkaz:
https://doaj.org/article/74ed0ae8a4344f6fbb931f1bfaf4706b
Autor:
Caitlin B. Conboy, Germán L. Vélez‐Reyes, Barbara R. Tschida, Hsiangyu Hu, Gabriel Kaufmann, Nicholas Koes, Bryant Keller, Clara Alsinet, Helena Cornellà, Roser Pinyol, Juan E. Abrahante, Nuri A. Temiz, Michael A. Linden, Khalid Amin, Timothy P. Kuka, Vincent W. Keng, Josep M. Llovet, Timothy K. Starr, David A. Largaespada
Publikováno v:
Hepatology Communications, Vol 3, Iss 11, Pp 1496-1509 (2019)
Each year, more than 25,000 people succumb to liver cancer in the United States, and this neoplasm represents the second cause of cancer‐related death globally. R‐spondins (RSPOs) are secreted regulators of Wnt signaling that function in developm
Externí odkaz:
https://doaj.org/article/0eab1ccaa58a47a08d90c0ba26613dba
Autor:
Jeffrey C. To, Amy P. Chiu, Barbara R. Tschida, Lilian H. Lo, Cynthia H. Chiu, Xiao-Xiao Li, Timothy P. Kuka, Michael A. Linden, Khalid Amin, Wing-Cheung Chan, Jason B. Bell, Branden S. Moriarity, David A. Largaespada, Vincent W. Keng
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100223- (2021)
Background & Aims: Zinc finger and BTB domain containing 20 (ZBTB20) has been implicated as a potential oncogene in liver cancer. However, knockout studies have shown it to be a transcriptional repressor of the alpha-foetoprotein (Afp) gene in adult
Externí odkaz:
https://doaj.org/article/58dd8d290ff94e908089e3e2954c131c
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary Figure S4. Serum metabolite profiles of experimental animals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24958c300980b21687e820e88e37876d
https://doi.org/10.1158/1541-7786.22516128
https://doi.org/10.1158/1541-7786.22516128
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Chronic hepatitis B viral (HBV) infection remains a high underlying cause for hepatocellular carcinoma (HCC) worldwide, while the genetic mechanisms behind this remain unclear. This study elucidated the mechanisms contributing to tumor development in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fc2b46122901b041db9bc0b9d8eb88
https://doi.org/10.1158/1541-7786.c.6541287
https://doi.org/10.1158/1541-7786.c.6541287
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary materials and methods for PCR and serum preparation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a5bd4d0aaaa7236c30697665b61ba3
https://doi.org/10.1158/1541-7786.22516116
https://doi.org/10.1158/1541-7786.22516116
Autor:
Vincent W. Keng, Nadia Warner, David A. Largaespada, Daniel K.W. Mok, Chi-On Chan, Dewi K. Rowlands, David E. Hinton, Regina C. Lo, Xiao-Xiao Li, Branden S. Moriarity, Lilian H. Lo, Tung-Ting Sham, Barbara R. Tschida, Amy P. Chiu
Supplementary Table S3. Up-stream regulator of IGF2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5638d21bde6004e9e8de9c4b122b36cb
https://doi.org/10.1158/1541-7786.22516119.v1
https://doi.org/10.1158/1541-7786.22516119.v1
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNET) are aggressive, poorly differentiated brain tumors with limited effective therapies. Using Sleeping Beauty (SB) transposon mutagenesis, we identified novel genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcfc7720d1848ea19440c3e7a8f431f
https://doi.org/10.1158/0008-5472.c.6511413.v1
https://doi.org/10.1158/0008-5472.c.6511413.v1
Autor:
David A. Largaespada, Vincent W. Keng, Adam J. Dupuy, Joseph H. Nadeau, Lewis R. Roberts, Ju Dong Yang, Aaron L. Sarver, Rachel A. Heuer, Pauline J. Beckmann, Khalid Amin, Michael A. Linden, Wendy A. Hudson, Sandra Wagner, Robert Hullsiek, Carlos A. Tierrablanca, Jesse D. Riordan, Lindsey A. Lee, Timothy P. Kuka, Nuri A. Temiz, Barbara R. Tschida
Oncoprints showing steatosis-associated CIS gene amplifications, deep deletions, and mutations occurring in at least 5% of all(S5), steatosis-associated(S6), and alcohol-associated(S7) TCGA HCC cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454cd20e521cb04dc3547458aa1f7623
https://doi.org/10.1158/0008-5472.22415118
https://doi.org/10.1158/0008-5472.22415118
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Figure S4. Shows ARHGAP36 expression in mouse and human neural tissue. Figure S5. Shows characterization of ARHGAP36 and Megf10 in C17.2 cells Figures S6-S7 show mechanistic analysis of FOXR2 in C17.2 and HSC1L cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c88fb8090e9d0f93c8d64bec0f20df6
https://doi.org/10.1158/0008-5472.22423053
https://doi.org/10.1158/0008-5472.22423053