Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Barbara Pioselli"'
Autor:
Matteo Storti, Maria Laura Faietti, Xabier Murgia, Chiara Catozzi, Ilaria Minato, Danilo Tatoni, Simona Cantarella, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Mar Vilanova, Ester Sánchez-Jiménez, Marina Gay, Marta Vilaseca, Gino Villetti, Barbara Pioselli, Fabrizio Salomone, Simone Ottonello, Barbara Montanini, Francesca Ricci
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Premature birth, perinatal inflammation, and life-saving therapies such as postnatal oxygen and mechanical ventilation are strongly associated with the development of bronchopulmonary dysplasia (BPD); these risk factors, alone or
Externí odkaz:
https://doaj.org/article/5ecdcfc35d2a4e6cae01ddf16f8df80b
Autor:
Cristina García-Mouton, Mercedes Echaide, Luis A. Serrano, Guillermo Orellana, Fabrizio Salomone, Francesca Ricci, Barbara Pioselli, Davide Amidani, Antonio Cruz, Jesús Pérez-Gil
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 256 (2023)
Pulmonary surfactant (PS) has been proposed as an efficient drug delivery vehicle for inhaled therapies. Its ability to adsorb and spread interfacially and transport different drugs associated with it has been studied mainly by different surface bala
Externí odkaz:
https://doaj.org/article/93795d80df1447528e8bb099804d4e54
Autor:
Giorgio Aquila, Yannick Regin, Xabier Murgia, Fabrizio Salomone, Costanza Casiraghi, Chiara Catozzi, Enrica Scalera, Matteo Storti, Francesca Stretti, Giancarlo Aquino, Giorgia Cavatorta, Roberta Volta, Carmelina Di Pasquale, Caterina Amato, Fabio Bignami, Davide Amidani, Barbara Pioselli, Elisa Sgarbi, Paolo Ronchi, Giuseppe Mazzola, Ignacio Valenzuela, Jaan Toelen
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1507 (2022)
Thiazolidinediones (TZDs) are potent PPARγ agonists that have been shown to attenuate alveolar simplification after prolonged hyperoxia in term rodent models of bronchopulmonary dysplasia. However, the pulmonary outcomes of postnatal TZDs have not b
Externí odkaz:
https://doaj.org/article/3deb22c045194f439472a544de6d3be1
Autor:
Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Francesca Ricci, Francesca Boscaro, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Federico Bianco, Fabrizio Salomone, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background The amount of surfactant deposited in the lungs and its overall pulmonary distribution determine the therapeutic outcome of surfactant replacement therapy. Most of the currently available methods to determine the intrapulmonary di
Externí odkaz:
https://doaj.org/article/979ca60013de43c6880ec022810ad441
Autor:
Xiaojing Guo, Siwei Luo, Davide Amidani, Claudio Rivetti, Giuseppe Pieraccini, Barbara Pioselli, Silvia Catinella, Xabi Murgia, Fabrizio Salomone, Yaling Xu, Ying Dong, Bo Sun
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230229 (2020)
Poractant alfa and Calsurf are two natural surfactants widely used in China for the treatment of neonatal respiratory distress syndrome, which are extracted from porcine and calf lungs, respectively. The purpose of this experimental study was to comp
Externí odkaz:
https://doaj.org/article/210f3f62b99b4b4aa3fe9c992c866f0b
Autor:
Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Fabrizio Salomone, Giuseppe Pieraccini, Haruo Usada, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 868 (2021)
Direct lung administration of budesonide in combination with surfactant reduces the incidence of bronchopulmonary dysplasia. Although the therapy is currently undergoing clinical development, the lung distribution of budesonide throughout the prematu
Externí odkaz:
https://doaj.org/article/3053385b04904c7695a92e4a2539806c
Autor:
Nina Kronqvist, Médoune Sarr, Anton Lindqvist, Kerstin Nordling, Martins Otikovs, Luca Venturi, Barbara Pioselli, Pasi Purhonen, Michael Landreh, Henrik Biverstål, Zigmantas Toleikis, Lisa Sjöberg, Carol V. Robinson, Nicola Pelizzi, Hans Jörnvall, Hans Hebert, Kristaps Jaudzems, Tore Curstedt, Anna Rising, Jan Johansson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The properties of many transmembrane or aggregation-prone proteins make them difficult to recombinantly express. Here the authors use a modified N-terminal domain of a spider silk protein to express and purify several difficult to express proteins at
Externí odkaz:
https://doaj.org/article/6e88916356bd45a19c0f201d1ebfd6e8
Autor:
Luca Ronda, Barbara Pioselli, Silvia Catinella, Fabrizio Salomone, Marialaura Marchetti, Stefano Bettati
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201926 (2018)
CHF5633 (Chiesi Farmaceutici, Italy) is a synthetic surfactant developed for respiratory distress syndrome replacement therapy in pre-term newborn infants. CHF5633 contains two phospholipids (dipalmitoylphosphatidylcholine and 1-palmitoyl-2oleoyl-sn-
Externí odkaz:
https://doaj.org/article/b18967a424914a9897066cac22e4fa84
Autor:
Francesca Ricci, Chiara Catozzi, Xabier Murgia, Brenda Rosa, Davide Amidani, Luca Lorenzini, Federico Bianco, Claudio Rivetti, Silvia Catinella, Gino Villetti, Maurizio Civelli, Barbara Pioselli, Carlo Dani, Fabrizio Salomone
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169190 (2017)
Nasal continuous positive airway pressure (nCPAP) is a widely accepted technique of non-invasive respiratory support in spontaneously-breathing premature infants with respiratory distress syndrome (RDS). Surfactant administration techniques compatibl
Externí odkaz:
https://doaj.org/article/a1c121a13fb748a0ae0b370e4f481510
Autor:
Maurizio Civelli, Virgilio P. Carnielli, Fabrizio Salomone, Xabi Murgia, Daniele De Luca, Barbara Pioselli, Silvia Catinella, Davide Amidani, Francesco Amadei, Gino Villetti, Elisa Sgarbi, Giuseppe Mazzola
Publikováno v:
Current Medicinal Chemistry. 29:526-590
Pulmonary surfactant is a complex lipoprotein mixture secreted into the alveolar lumen by type 2 pneumocytes, which is composed by tens of different lipids (approximately 90% of its entire mass) and surfactant proteins (approximately 10% of the mass)