Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Barbara Petzuch"'
Autor:
Barbara Petzuch, Agnès Bénardeau, Lucas Hofmeister, Jutta Meyer, Elke Hartmann, Mira Pavkovic, Ilka Mathar, Peter Sandner, Heidrun Ellinger-Ziegelbauer
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 187(1)
Micro-RNAs (miRNAs) are regulators of gene expression and play an important role in physiological homeostasis and disease. In biofluids, miRNAs can be found in protein complexes or in extracellular vesicles (EVs). Altered urinary miRNAs are reported
Autor:
Ellen Fritsche, Jördis Klose, Ulrike Hübenthal, Jenny Baumann, René Deenen, Clara Siebert, Stefan Masjosthusmann, Daniel Becker, Katharina Dach, Karl Köhrer, Barbara Petzuch, Julia Tigges, Marta Barenys
Publikováno v:
Toxicology and applied pharmacology. 354
It is widely accepted that human brain development has unique features that cannot be represented by rodents. Obvious reasons are the evolutionary distance and divergent physiology. This might lead to false predictions when rodents are used for safet
Autor:
Albert Braeuning, Eva Zeller, Ulrich M. Zanger, Michael Schwarz, Thomas S. Weiss, Maria Thomas, Werner Schroth, Janina Johänning, Silvia Vetter, Ute Hofmann, Barbara Petzuch
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 43(11)
Enzymatic conversion of most xenobiotic compounds is accomplished by hepatocytes in the liver, which are also an important target for the manifestation of the toxic effects of foreign compounds. Most cell lines derived from hepatocytes lack important