Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Barbara Pernaute"'
Autor:
Kimberley M. Reid, Juan Miguel Sanchez-Nieto, Sandra Terrasse, Danilo Faccenda, Barbara Pernaute, Michelangelo Campanella, Tristan A. Rodriguez, Bradley S. Cobb
Publikováno v:
Cells, Vol 12, Iss 15, p 1957 (2023)
MicroRNAs (miRNAs) are important regulators of embryonic stem cell (ESC) biology, and their study has identified key regulatory mechanisms. To find novel pathways regulated by miRNAs in ESCs, we undertook a bioinformatics analysis of gene pathways di
Externí odkaz:
https://doaj.org/article/d16df6b24a13482494dd98f3329779b3
Autor:
Thomas Spruce, Mireya Plass, André Gohr, Debashish Ray, María Martínez de Lagrán, Gregor Rot, Ana Nóvoa, Demian Burguera, Jon Permanyer, Marta Miret, Hong Zheng, Maurice S Swanson, Quaid Morris, Moises Mallo, Mara Dierssen, Timothy R Hughes, Barbara Pernaute, Manuel Irimia
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001615 (2022)
Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specializati
Externí odkaz:
https://doaj.org/article/123842fa9e434a1097df0caff61e1e6d
Autor:
Nieves Peltzer, Eva Rieser, Lucia Taraborrelli, Peter Draber, Maurice Darding, Barbara Pernaute, Yutaka Shimizu, Aida Sarr, Helena Draberova, Antonella Montinaro, Juan Pedro Martinez-Barbera, John Silke, Tristan A. Rodriguez, Henning Walczak
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 153-165 (2014)
Summary: Linear ubiquitination is crucial for innate and adaptive immunity. The linear ubiquitin chain assembly complex (LUBAC), consisting of HOIL-1, HOIP, and SHARPIN, is the only known ubiquitin ligase that generates linear ubiquitin linkages. HOI
Externí odkaz:
https://doaj.org/article/fe44decd3f4d43868515aa18741bdad2
Autor:
Juan Miguel Sanchez, Di Hu, Salvador Pérez-Montero, Elmir Mahammadov, Shankar Srinivas, Margarida Sancho, David Carling, Alistair Green, Sarah Bowling, Tamzin Zawadzki, Mohammad M. Karimi, Ana Lima, Marian Dore, Nick S. Jones, Aida Di Gregorio, Jörg Burgstaller, Barbara Pernaute, Thomas Kolbe, Antonio Scialdone, Tristan A. Rodriguez, Gabriele Lubatti
Publikováno v:
Nature metabolism
Nat. Metab. 3, 1091-1108 (2021)
Nat. Metab. 3, 1091-1108 (2021)
Cell competition is emerging as a quality-control mechanism that eliminates unfit cells in a wide range of settings from development to the adult. However, the nature of the cells normally eliminated by cell competition and what triggers their elimin
Autor:
Christopher D. R. Wyatt, Barbara Pernaute, André Gohr, Marta Miret-Cuesta, Lucia Goyeneche, Quirze Rovira, Marion C. Salzer, Elvan Boke, Ozren Bogdanovic, Sophie Bonnal, Manuel Irimia
Publikováno v:
Science advances. 8(15)
Transition from maternal to embryonic transcriptional control is crucial for embryogenesis. However, alternative splicing regulation during this process remains understudied. Using transcriptomic data from human, mouse, and cow preimplantation develo
Autor:
Timothy P. Hughes, Hong Zheng, Gregor Rot, Debashish Ray, Quaid Morris, Demian Burguera, Thomas Spruce, Manuel Irimia, Marta Miret, Mara Dierssen, Mireya Plass, Andre Gohr, Ana Nóvoa, Jon Permanyer, Moisés Mallo, María Martínez de Lagrán, Barbara Pernaute, Maurice S. Swanson
Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specializati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156e9db4133688631866527976993058
https://doi.org/10.1101/2021.09.08.459166
https://doi.org/10.1101/2021.09.08.459166
Autor:
Manuel Irimia, Ozren Bogdanovic, Goyeneche L, Bonnal S, Barbara Pernaute, Wyatt Cdr, Rovira Q, Miret-Cuesta M, Andre Gohr
The transition from maternal to embryonic transcriptional control is a crucial step in embryogenesis. However, how alternative splicing is regulated during this process and how it contributes to early development is unknown. Using transcriptomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a7aa6340adbdd4043dc545c08eeec70
https://doi.org/10.1101/2020.11.25.397794
https://doi.org/10.1101/2020.11.25.397794
Autor:
Mohammad M. Karimi, Elmir Mahammadov, Nick S. Jones, Salvador Perez Montero, Alistair Green, Aida Di Gregorio, Margarida Sancho, Juan Miguel Sanchez, Shankar Srinivas, Di Hu, Ana Lima, Sarah Bowling, David Carling, Tamzin Zawadzki, Tristan A. Rodriguez, Jörg Burgstaller, Marian Dore, Barbara Pernaute, Antonio Scialdone, Gabriele Lubatti
Cell competition is emerging as a quality control mechanism that eliminates unfit cells in a wide range of settings from development to the adult. However, the nature of the cells normally eliminated by cell competition and what triggers their elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d690490be44e34ed86388c74e9c2d950
https://doi.org/10.1101/2020.01.15.900613
https://doi.org/10.1101/2020.01.15.900613
Autor:
Salvador Pérez-Montero, Katerina Lawlor, Gianmaria Liccardi, Barbara Pernaute, Tristan A. Rodriguez, Pascal Meier, Aida Di Gregorio, Alejandra Tomas, Juan Miguel Sánchez Nieto, Ana Lima, Ivana Barbaric, Guy A. Rutter, Sarah Bowling
The changes that drive differentiation create a large potential for the emergence of abnormal cells that need to be removed before they contribute to further development or the germline. This removal is in part achieved by cells becoming hypersensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7fdbb18eb26bafc791162575a0e866
Autor:
Scott William Roy, Gemma Marfany, Luis Puelles, Amanda Denuc, José Luis Ferran, Manuel Irimia, Jordi Garcia-Fernàndez, Barbara Pernaute
Publikováno v:
RNA Biology. 9:12-21
The structural complexity of the vertebrate brain is mirrored by its unparalleled transcriptome complexity. In particular, two post-transcriptional processes, alternative splicing and RNA editing, greatly diversify brain transcriptomes. Here we repor