Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Barbara Pavan"'
Autor:
Giada Botti, Barbara Pavan, Anna Bianchi, Luca Ferraro, Sarah Beggiato, Federica Brugnoli, Valeria Bertagnolo, Alessandro Dalpiaz
Publikováno v:
Journal of Functional Foods, Vol 119, Iss , Pp 106331- (2024)
Poor oral bioavailability limits chlorogenic acid (CGA) benefits on the gut-brain axis. In this study we demonstrate the existence of an active circadian-dependent efflux for the CGA intestinal permeation, leading to greater bioavailability in the ev
Externí odkaz:
https://doaj.org/article/1ae5c38bdc01451c82045a0c9fb5c267
Autor:
Marika Faiella, Giada Botti, Alessandro Dalpiaz, Lorenzo Gnudi, Aurélie Goyenvalle, Barbara Pavan, Daniela Perrone, Matteo Bovolenta, Elena Marchesi
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1023 (2024)
Delivery represents a major hurdle to the clinical advancement of oligonucleotide therapeutics for the treatment of disorders such as Duchenne muscular dystrophy (DMD). In this preliminary study, we explored the ability of 2′-O-methyl-phosphorothio
Externí odkaz:
https://doaj.org/article/f564dd01072d4f529e4c43386b9bc6fe
Autor:
Lindomar Alberto Lerin, Giada Botti, Alessandro Dalpiaz, Anna Bianchi, Luca Ferraro, Chaimae Chaibi, Federico Zappaterra, Domenico Meola, Pier Paolo Giovannini, Barbara Pavan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6263 (2024)
Ferulic acid (Fer) and geraniol (Ger) are natural compounds whose antioxidant and anti-inflammatory activity confer beneficial properties, such as antibacterial, anticancer, and neuroprotective effects. However, the short half-lives of these compound
Externí odkaz:
https://doaj.org/article/29292328082746ebb1cc97b9bc3e2108
Autor:
Barbara Pavan
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 481-482 (2024)
Externí odkaz:
https://doaj.org/article/153a84cb18e64befa15490ab45aa1dab
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 389-395 (2023)
In the current landscape of endothelial cell isolation for building in vitro models of the blood-brain barrier, our work moves towards reproducing the features of the neurovascular unit to achieve glial compliance through an innovative biomimetic coa
Externí odkaz:
https://doaj.org/article/4665c543721348bda1d4697d14ec7d67
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105477- (2022)
Summary: New evidence is emerging about the dynamics of interaction between circadian rhythms and brain waves, whose coordination occurs through the entrainment process. The so-called “oscillopathies” or dysfunctions in synchronization of neurona
Externí odkaz:
https://doaj.org/article/9f054af586d14f25b550305a0eab3e92
Autor:
Giovanna Rassu, Milena Sorrenti, Laura Catenacci, Barbara Pavan, Luca Ferraro, Elisabetta Gavini, Maria Cristina Bonferoni, Paolo Giunchedi, Alessandro Dalpiaz
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1578 (2023)
Phytochemicals, produced as secondary plant metabolites, have shown interesting potential therapeutic activities against neurodegenerative diseases and cancer. Unfortunately, poor bioavailability and rapid metabolic processes compromise their therape
Externí odkaz:
https://doaj.org/article/45bbb6b79f11408090a1c691002c16d8
Autor:
Barbara Pavan, Anna Bianchi, Giada Botti, Luca Ferraro, Maria Chiara Valerii, Enzo Spisni, Alessandro Dalpiaz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1800 (2023)
Eugenol, cinnamaldehyde and D-limonene, the main components of natural essential oils, are endowed with antioxidant and anti-inflammatory properties which allow them to induce beneficial effects on intestinal, cardiac and neuronal levels. In order to
Externí odkaz:
https://doaj.org/article/f0d3b5c3e25e4da2a020f604e4676a0d
Publikováno v:
Nanomaterials, Vol 11, Iss 8, p 2022 (2021)
Poly(3,4-ethylenedioxythiophene)-Nafion (PEDOT:Nafion) is emerging as a promising alternative to PEDOT-polystyrene sulfonate (PEDOT:PSS) in organic bioelectronics. However, the biocompatibility of PEDOT:Nafion has not been investigated to date, limit
Externí odkaz:
https://doaj.org/article/bec082c932dd473386c851f09c648664
Targeting Systems to the Brain Obtained by Merging Prodrugs, Nanoparticles, and Nasal Administration
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1144 (2021)
About 40 years ago the lipidization of hydrophilic drugs was proposed to induce their brain targeting by transforming them into lipophilic prodrugs. Unfortunately, lipidization often transforms a hydrophilic neuroactive agent into an active efflux tr
Externí odkaz:
https://doaj.org/article/bc066b5044cd47e7aea201825df8b121