Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Barbara N. Walter"'
Autor:
Y.-H. Chen, Esther Guzman, Laurie B. Owen, J.L. Langowski, Ameae M. Walker, A. De Guzman, Barbara N. Walter, H.K. Muller, H.-L. Lo
Publikováno v:
Journal of Neuroimmunology. 170:31-40
The effects of two major forms of prolactin (PRL) were examined on delayed type hypersensitivity (DTH) responses to Candida albicans . Unmodified PRL (U-PRL) had no effect on the DTH response, whereas a molecular mimic of phosphorylated PRL (S179D PR
Publikováno v:
Journal of Biological Chemistry. 278:25428-25434
Proapoptotic gene transfer to promote death or to augment killing by DNA-damaging agents represents a promising strategy for cancer therapy. We have constructed an adenoviral Tet-Off trade mark vector with tightly controlled expression of Bid (Ad-Bid
Publikováno v:
European Journal of Biochemistry. 267:4414-4421
The p21-activated protein kinase gamma-PAK from rabbit, expressed in insect cells, is activated following binding of Cdc42(GTPgammaS). The rate of autophosphorylation is increased fivefold and the protein kinase activity 13-fold, as measured with the
Autor:
Rolf Jakobi, Polygena T. Tuazon, Barbara N. Walter, Jolinda A. Traugh, Zhongdong Huang, Gerald Litwack, Emad S. Alnemri
Publikováno v:
Journal of Biological Chemistry. 273:28733-28739
p21-activated protein kinase γ-PAK (Pak2, PAK I) is cleaved by CPP32 (caspase 3) during apoptosis and plays a key role in regulation of cell death. In vitro, CPP32 cleaves recombinant γ-PAK into two peptides; 1–212 contains the majority of the re
Autor:
Paul M. Guyre, Marianne Murphy, Barbara N. Walter, Neil A Fanger, Larry Pike-Nobile, Jeffrey L. Browning, Carl F. Ware, Lois B. Epstein
Publikováno v:
Cell Death & Differentiation. 5:497-505
The lymphotoxin beta receptor (LTbetaR), and its ligand, LTalpha1beta2, have been proposed to play a key role in the development and organization of lymphoid tissues. The LTbetaR is expressed on a variety of human primary and transformed cells, but s
Publikováno v:
Scopus-Elsevier
Cytotoxic T cells use Fas (CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, to eliminate virus-infected cells by activation of the apoptotic pathway for cell death. The adenovirus E3 region encodes several proteins that modify
Autor:
Todd L. VanArsdale, Barbara N. Walter, John C. Reed, Elliott Kieff, Carl F. Ware, George Mosialos, Walker R. Force, Sammee L. VanArsdale
Publikováno v:
Proceedings of the National Academy of Sciences. 94:2460-2465
The binding of heterotrimeric lymphotoxin, LTα1β2, to the LTβ receptor (LTβR), a member of the tumor necrosis factor receptor (TNFR) superfamily, induces nuclear factor κB (NF-κB) activation and cell death in HT29 adenocarcinoma cells. We now s
Autor:
Carol Otten-Evans, Kendall M. Mohler, Carl F. Ware, Paul D. Crowe, Barbara N. Walter, Roy A. Black
Publikováno v:
The Journal of Experimental Medicine
TNF is synthesized as a 26-kD membrane-anchored precursor and is proteolytically processed at the cell surface to yield the mature secreted 17-kD polypeptide. The 80-kD tumor necrosis factor (TNF) receptor (TNFR80) is also proteolytically cleaved at
Autor:
Jeffrey Browning, Wenie S. Din, Raymond G. Goodwin, Craig A. Smith, Barbara Ehrenfels, Todd L. VanArsdale, Barbara N. Walter, Paul D. Crowe, Carl F. Ware, Catherine Hession
Publikováno v:
Science. 264:707-710
Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. The cell surface form of LT-alpha is assembled during
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 289:231-243
We have established a system for the study of DNA-sequence specificity at a functionally heterozygous thymidine kinase ( tk ) locus in a human lymphoblastoid cell line (TK6). Characterization of the parental locus demonstrated that the 2 tk alleles w