Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Barbara N. Timmermann"'
Autor:
Chitra Subramanian, Katie K. Spielbauer, Robin Pearce, Kevin J. Kovatch, Mark E. Prince, Barbara N. Timmermann, Mark S. Cohen
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5398 (2022)
Treatment regimens for head and neck squamous cell carcinoma (HNSCC) typically include cisplatin and radiotherapy and are limited by toxicities. We have identified naturally derived withalongolide A triacetate (WGA-TA) from Physalis longifolia as a l
Externí odkaz:
https://doaj.org/article/dfc5e4aab9304770bd8b533cb09e74ad
Autor:
Georg Petschenka, Colleen S. Fei, Juan J. Araya, Susanne Schröder, Barbara N. Timmermann, Anurag A. Agrawal
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
A major prediction of coevolutionary theory is that plants may target particular herbivores with secondary compounds that are selectively defensive. The highly specialized monarch butterfly (Danaus plexippus) copes well with cardiac glycosides (inhib
Externí odkaz:
https://doaj.org/article/80e8198b154c46568f0b1aff1f207c47
Autor:
Monica Chanda, Mark S. Cohen, Nina Zhang, Ton Wang, Brian S. J. Blagg, Chitra Subramanian, Barbara N. Timmermann, Jackee N Sanchez, Gary Shanguan
Publikováno v:
Melanoma research. 31(3)
Melanoma remains the most aggressive and fatal form of skin cancer, despite several FDA-approved targeted chemotherapies and immunotherapies for use in advanced disease. Of the 100 350 new patients diagnosed with melanoma in 2020 in the US, more than
Publikováno v:
Natural product communications. 14(1)
We report relative bioactivities of extracts prepared from a large collection of plants from three national parks in Panama. Over 181 plants were collected, taxonomically identified and their detannified dichloromethane (DCM)-methanolic extracts were
Autor:
Barbara N. Timmermann, Patrick T. Grogan, Valerie P. Opipari, Chitra Subramanian, Mark S. Cohen
Publikováno v:
Oncotarget
// Chitra Subramanian 1 , Patrick T. Grogan 2 , Valerie P. Opipari 3 , Barbara N. Timmermann 4 and Mark S. Cohen 1, 5 1 Department of Surgery, University of Michigan, Ann Arbor, MI, USA 2 Department of Internal Medicine, University of Wisconsin, Madi
Autor:
Chitra Subramanian, Mark S. Cohen, Anna Schwendeman, Peter T. White, James J. Moon, Rui Kuai, Barbara N. Timmermann
Publikováno v:
International Journal of Nanomedicine
Rui Kuai,1,2,* Chitra Subramanian,3,* Peter T White,3,* Barbara N Timmermann,4 James J Moon,1,2,5 Mark S Cohen,3,6 Anna Schwendeman1,2 1Department of Pharmaceutical Sciences, College of Pharmacy, 2Biointerfaces Institute, University of Michigan, 3Dep
Autor:
Jeffrey C. Oliver, Barbara N. Timmermann, Kathleen L. Prudic, David B. Ritland, Daniel R. Papaj
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-9 (2019)
Communications Biology
Communications Biology
Mimics should not exist without their models, yet often they do. In the system involving queen and viceroy butterflies, the viceroy is both mimic and co-model depending on the local abundance of the model, the queen. Here, we integrate population sur
Autor:
Jennifer B. Frye, Janice Oyarzo, Janet L. Funk, Barbara N. Timmermann, Huaping Zhang, Jianling Chen
Publikováno v:
PharmaNutrition. 4:123-131
Ginger and its extracts have been used traditionally as anti-inflammatory remedies, with a particular focus on the medicinal properties of its phenolic secondary metabolites, the gingerols. Consistent with these uses, potent anti-arthritic effects of
Autor:
Barbara N. Timmermann, Huaping Zhang
Publikováno v:
Journal of Natural Products. 79:732-742
A classic withanolide is defined as a highly oxygenated C28 ergostane-type steroid that is characterized by a C22-hydroxy-C26-oic acid δ-lactone in the nine-carbon side chain. Analysis of the reported (13)C NMR data of classic withanolides with hydr
Autor:
Mark S. Cohen, Qing Zhu, Barbara N. Timmermann, Chitra Subramanian, Peter T. White, Robert J. Gallagher, Brian S. J. Blagg, Huaping Zhang, Huiping Zhao
Publikováno v:
Surgery. 159:142-151
Thyroid cancer stem cells (CSCs) with ALDH and CD44 markers contribute to tumor growth and aggressiveness. We hypothesized that novel HSP90 inhibitors (KU711, WGA-TA) and 17-AAG can effectively target the function of thyroid CSCs in vitro and prevent