Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Barbara N Borsos"'
Autor:
Nóra Ördög, Barbara N Borsos, Hajnalka Majoros, Zsuzsanna Ujfaludi, Gabriella Pankotai-Bodó, Sarolta Bankó, Farkas Sükösd, Levente Kuthi, Tibor Pankotai
Publikováno v:
Translational Oncology, Vol 20, Iss , Pp 101420- (2022)
Patients diagnosed with clear cell renal cell carcinoma (ccRCC) have poor prognosis for recurrence and approximately 30–40% of them will later develop metastases. For this reason, the appropriate diagnosis and the more detailed molecular characteri
Externí odkaz:
https://doaj.org/article/5cd5830857e44351832eecd8a1fa4822
Autor:
Barbara N Borsos, Vasiliki Pantazi, Zoltán G Páhi, Hajnalka Majoros, Zsuzsanna Ujfaludi, Ivett Berzsenyi, Tibor Pankotai
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267615 (2022)
DNA double-strand breaks are one of the most deleterious lesions for the cells, therefore understanding the macromolecular interactions of the DNA repair-related mechanisms is essential. DNA damage triggers transcription silencing at the damage site,
Externí odkaz:
https://doaj.org/article/4bf93282b3b648659a565bc9f9956c02
Autor:
Zoltan Pahi, Zsuzsanna Kiss, Orbán Komonyi, Barbara N Borsos, Laszlo Tora, Imre M Boros, Tibor Pankotai
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142226 (2015)
In eukaryotes the TFIID complex is required for preinitiation complex assembly which positions RNA polymerase II around transcription start sites. On the other hand, histone acetyltransferase complexes including SAGA and ATAC, modulate transcription
Externí odkaz:
https://doaj.org/article/d49ba4d64f114eb899718b7eab1704c7
Autor:
Nikolett Barta, Nóra Ördög, Vasiliki Pantazi, Ivett Berzsenyi, Barbara N. Borsos, Hajnalka Majoros, Zoltán G. Páhi, Zsuzsanna Ujfaludi, Tibor Pankotai
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1523 (2023)
DNA repair pathways trigger robust downstream responses, making it challenging to select suitable reference genes for comparative studies. In this study, our goal was to identify the most suitable housekeeping genes to perform comparable molecular an
Externí odkaz:
https://doaj.org/article/dc8168d8f30040ee82d0dd7759118539
Autor:
Bence Nagy-Mikó, Orsolya Németh-Szatmári, Réka Faragó-Mészáros, Aliz Csókási, Bence Bognár, Nóra Ördög, Barbara N. Borsos, Hajnalka Majoros, Zsuzsanna Ujfaludi, Orsolya Oláh-Németh, Aliz Nikolényi, Ágnes Dobi, Renáta Kószó, Dóra Sántha, György Lázár, Zsolt Simonka, Attila Paszt, Katalin Ormándi, Tibor Pankotai, Imre M. Boros, Zoltán Villányi, András Vörös
We aimed to investigate the contribution of co-translational protein aggregation to the chemotherapy resistance of tumor cells. Increased co-translational protein aggregation reflects altered translation regulation that may have the potential to buff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58b565ea54e71304666d0a63b023cc12
https://doi.org/10.1101/2023.01.13.523908
https://doi.org/10.1101/2023.01.13.523908
Autor:
Barbara N. Borsos, Zoltán G. Páhi, Zsuzsanna Ujfaludi, Farkas Sükösd, Alíz Nikolényi, Sarolta Bankó, Gabriella Pankotai-Bodó, Orsolya Oláh-Németh, Tibor Pankotai
Publikováno v:
Cells
Cells; Volume 11; Issue 17; Pages: 2721
Cells; Volume 11; Issue 17; Pages: 2721
Breast cancer is the most frequent cancer with a high fatality rate amongst women worldwide. Diagnosing at an early stage is challenging, and due to the limitations of the currently used techniques, including mammography and imaging diagnostics, it s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8dae6b7fe34a466fab526578bf2e1e
https://pubmed.ncbi.nlm.nih.gov/36078129
https://pubmed.ncbi.nlm.nih.gov/36078129
Publikováno v:
Scientific Reports. 12
Ubiquitylation is critical for preventing aberrant DNA repair and for efficient maintenance of genome stability. As deubiquitylases (DUBs) counteract ubiquitylation, they must have a great influence on many biological processes, including DNA damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50951ca17dce3d827bbe71559640a5b5
https://doi.org/10.1038/s41598-022-09703-x
https://doi.org/10.1038/s41598-022-09703-x
Autor:
Houjiang Zhou, Paul L. Appleton, Miroslav Novak, Florian Weiland, Rachel Toth, Vasiliki Pantazi, Michael E Morgan, Barbara N. Borsos, John Rouse, Meghan Slean, Taran Khanam, Tibor Pankotai, Thomas D. Carroll, Ivan Muñoz
Publikováno v:
The EMBO Journal
Mutations in the gene encoding the CDKL5 kinase are among the most common genetic causes of childhood epilepsy and can also give rise to the severe neurodevelopmental condition CDD (CDKL5 deficiency disorder). Despite its importance for human health,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3d10e294aab6c1073385a05713b2dc
https://doi.org/10.15252/embj.2021108271
https://doi.org/10.15252/embj.2021108271
Publikováno v:
Journal of Visualized Experiments.
Cells are continuously exposed to various DNA damaging agents, inducing different cellular responses. Applying biochemical and genetic approaches is essential in revealing cellular events associated with the recruitment and assembly of DNA repair com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac92faa0f2d32151efe13a4ae72f08a
https://doi.org/10.3791/62175
https://doi.org/10.3791/62175
Autor:
Zsuzsanna Újfaludi, Zoltán Gábor Páhi, Lajos Haracska, Imre Boros, Hajnalka Majoros, Tibor Pankotai, Mónika Mórocz, Barbara N. Borsos
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8500, p 8500 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8500, p 8500 (2021)
UV-induced DNA damage response and repair are extensively studied processes, as any malfunction in these pathways contributes to the activation of tumorigenesis. Although several proteins involved in these cellular mechanisms have been described, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3965372e055928e351fa6557065cc16f
https://pubmed.ncbi.nlm.nih.gov/34445206
https://pubmed.ncbi.nlm.nih.gov/34445206