Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Barbara Mioduszewska"'
Autor:
Witold Konopka, Kamila Duniec, Barbara Mioduszewska, Tomasz Proszynski, Jacek Jaworski, Leszek Kaczmarek
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 283-292 (2005)
To advance our understanding of the central nervous system, there is a need for refined approaches to control gene expression in neuronal culture as well as in the brain in vivo. In this study, we have applied a doxycycline-responsive Tet system to o
Externí odkaz:
https://doaj.org/article/275187bdf0534baebc197f6d3a353e1c
Autor:
Witold Konopka, Evgeni V. Nikolaev, Barbara Mioduszewska, Zofia M. Lasiecka, Marcin Wawrzyniak, Filip A. Konopacki, Grzegorz M. Wilczynski, Dorota Owczarek, Adam Gorlewicz, Kamila Duniec, Piotr Michaluk, Leszek Kaczmarek, Ole Petter Ottersen, Pawel Okulski, Werner Zuschratter, Dariusz C. Górecki, Ewa Wilczek, Monika Malinowska, Agnieszka Walczak, Lukasz Kolodziej
Publikováno v:
The Journal of Cell Biology
Temporal lobe epilepsy (TLE) is a devastating disease in which aberrant synaptic plasticity plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic enzyme and a key pathogenic factor in two animal models of TLE: kainate-e
Autor:
Jacek Jaworski, Katarzyna Zybura, Marcin Rylski, Barbara Mioduszewska, Piotr Michaluk, Leszek Kaczmarek, Renata Amborska
Publikováno v:
Journal of Biological Chemistry; Vol 283
Membrane depolarization controls long lasting adaptive neuronal changes in brain physiology and pathology. Such responses are believed to be gene expression-dependent. Notably, however, only a couple of gene repressors active in nondepolarized neuron
Autor:
Leszek Kaczmarek, Kamila Duniec, Barbara Mioduszewska, Jacek Jaworski, Witold Konopka, Tomasz J. Prószyński
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 283-292 (2005)
To advance our understanding of the central nervous system, there is a need for refined approaches to control gene expression in neuronal culture as well as in the brain in vivo. In this study, we have applied a doxycycline-responsive Tet system to o
Publikováno v:
Journal of Neurochemistry. 87:1313-1320
The acronym ICER (inducible cAMP early repressor) refers to a group of four proteins produced from the CREM/ICER gene due to use of an internal promoter (P2) placed in an intron of the CREM (cAMP responsive element modulator) gene. The ICER proteins
Autor:
Wojciech Dudek, Anna Polus, Joanna Skrzeczynska-Moncznik, Joanna Kulig, Tomasz J. Prószyński, Adriana Balwierz, Urszula Czech, Barbara Mioduszewska, Robert K. Filipkowski, Leszek Kaczmarek, Piotr Kołodziejczyk, Juliusz Pryjma, Aldona Dembinska-Kiec
Objectives: Angiogenesis, the process of formation of blood vessels, is essential for many physiological as well as pathological processes. It has been shown that human adipose tissue contains a population of non‐characterized cells, called stromal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124cb43249ef33db0197bd60a65b419
https://europepmc.org/articles/PMC6496779/
https://europepmc.org/articles/PMC6496779/
Publikováno v:
Journal of neuroscience research. 86(1)
Programmed cell death involving gene regulation and de novo protein synthesis is a major component of both normal development and a number of disease conditions. Hence, knowledge of its mechanisms, especially transcription factors, that regulate expr
Autor:
Dariusz C. Górecki, Leszek Kaczmarek, Grzegorz M. Wilczynski, Ole Petter Ottersen, Jacek Jaworski, Lukasz Kolodziej, Barbara Mioduszewska, Joanna Dzwonek, Piotr Michaluk
Publikováno v:
The Journal of biological chemistry. 282(22)
Matrix metalloproteinase-9 has recently emerged as an important molecule in control of extracellular proteolysis in the synaptic plasticity. However, no synaptic targets for its enzymatic activity had been identified before. In this report, we show t
Autor:
Jan, Pláteník, Vladimír J, Balcar, Yukio, Yoneda, Barbara, Mioduszewska, Richard, Buchal, Radovan, Hynek, Lukasz, Kilianek, Nobuyuki, Kuramoto, Grzegorz, Wilczynski, Kiyokazu, Ogita, Yoichi, Nakamura, Leszek, Kaczmarek
Publikováno v:
Journal of neurochemistry. 95(5)
Cyclic AMP response element binding protein (CREB) is a constitutive transcription factor that activates transcription following stimulus-dependent phosphorylation at Ser133, implicated in synaptic plasticity and neuronal survival pathways. The preva
Autor:
Jan Albrecht, Agata Klejman, Michal Hetman, Erzsebet Szatmari, Barbara Mioduszewska, Michal Wegrzynowicz
Publikováno v:
Neurochemistry international. 47(1-2)
The occurrence, nature and prevention of ammonia-induced cell death were assayed in cultured primary cortical neurons from newborn rats. Treatment with 1-10 mM ammonium chloride for 24 or 48 h, dose-dependently decreased neuronal survival (MTT assay)