Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Barbara Malitschek"'
Autor:
Gábor Nyiri, Akos Kulik, Kazuhiko Nakadate, Barbara Malitschek, Bernhard Bettler, Takuya Notomi, Ryuichi Shigemoto
Publikováno v:
European Journal of Neuroscience. 15:291-307
Metabotropic gamma-aminobutyric acid receptors (GABA(B)Rs) are involved in modulation of synaptic transmission and activity of cerebellar and thalamic neurons. We used subtype-specific antibodies in pre- and postembedding immunohistochemistry combine
Publikováno v:
The Journal of Comparative Neurology. 431:182-197
Although studies in the visual cortex have found gamma-aminobutyric acid B (GABA(B)) receptor-mediated pre- and postsynaptic inhibitory effects on neurons, the subcellular localization of GABA(B) receptors in different types of cortical neurons and s
Autor:
Barbara Malitschek, Jakob Heid, Cécile Joly, Klemens Kaupmann, Stephan Urwyler, Johannes Mosbacher, Jean-Philippe Pin, Wolfgang Froestl, Thierry Galvez, Laurent Prézeau, Bernhard Bettler, Isabelle Brabet
Publikováno v:
Molecular Pharmacology. 57:419-426
The gamma-aminobutyric acid (GABA) receptor type B (GABA(B)R) is constituted of at least two homologous proteins, GABA(B)R1 and GABA(B)R2. These proteins share sequence and structural similarity with metabotropic glutamate and Ca(2+)-sensing receptor
Autor:
P J Conn, Otmar D. Wiestler, Christian E. Elger, Albert J. Becker, Ingmar Blümcke, M Plaschke, Barbara Malitschek, Robert Nitsch, Ailing A. Lie, Johannes Schramm, Rainer Kuhn, Heinz Beck, Karsten Behle
Publikováno v:
Annals of Neurology. 47:26-35
Selective hippocampal cell loss and altered neurotransmitter receptor expression have been proposed as pathogenic mechanisms in the development of chronic mesial temporal lobe epilepsy (TLE). Studies in animal models point to metabotropic glutamate r
Autor:
Barbara Malitschek, Klemens Kaupmann, Jean-Philippe Pin, Torsten Pfaff, Bernhard Bettler, Laurent Prézeau, Andreas Karschin
Publikováno v:
European Journal of Neuroscience. 11:2874-2882
Here we present a novel isoform of the metabotropic G-protein-coupled receptor for gamma-aminobutyric acid (GABA). The isoform, termed GABA(B)R1c (R1c), differs from the recently identified R1a and R1b receptors by an in-frame insertion of 31 amino a
Autor:
Helmut Bittiger, Jean-Philippe Pin, Barbara Malitschek, Cecile Joly, Klemens Kaupmann, Bernhard Bettler, Marie-Laure Parmentier, Wolfgang Froestl, Thierry Galvez, Rainer Kuhn
Publikováno v:
Journal of Biological Chemistry. 274:13362-13369
The gamma-aminobutyric acid type B (GABAB) receptor is distantly related to the metabotropic glutamate receptor-like family of G-protein-coupled receptors (family 3). Sequence comparison revealed that, like metabotropic glutamate receptors, the extra
Autor:
Jakob Heid, Pascal Beck, Andreas Karschin, Barbara Malitschek, Bernhard Bettler, Serge Bischoff, Wolfgang Froestl, Ákos Kulik, Ryuichi Shigemoto, Klemens Kaupmann, Johannes Mosbacher, Valerie Schuler
Publikováno v:
Nature. 396:683-687
B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G-protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cycla
Autor:
Barbara Malitschek, Rainer Kuhn, Peter Koulen, Heinz Wässle, Bernhard Bettler, Johann Helmut Brandstätter
Publikováno v:
European Journal of Neuroscience. 10:1446-1456
The recently cloned GABA(B) receptors were localized in rat retina using specific antisera. Immunolabelling was detected in the inner and outer plexiform layers (IPL, OPL), and in a number of cells in the inner nuclear layer and the ganglion cell lay
Autor:
Thomas Knöpfel, G. Casabona, F. Nicoletti, Agata Copani, Maria Angela Sortino, Pier Luigi Canonico, Grazia Aleppo, C. Ventra, Rainer Kuhn, Barbara Malitschek
Publikováno v:
European Journal of Neuroscience. 8:2407-2415
We have characterized the expression pattern and pharmacological profile of activation of metabotropic glutamate receptors (mGluRs) in immortalized, gonadotropin releasing hormone (GnRH)-secreting GT1-7 cells, which represent a homogeneous cellular p
Publikováno v:
Brain Research. 741:75-81
It has been proposed that neurotransmitter signalling can occur between axons and glia in the mammalian optic nerve in the absence of synaptic specialisations, and that this may be glutamate mediated. Here, the cellular distribution of five metabotro