Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Barbara M.A. van Vugt-Lussenburg"'
Autor:
Bérénice Collet, Barbara M.A. van Vugt-Lussenburg, Kees Swart, Rick Helmus, Matthijs Naderman, Eva de Rijke, Merete Eggesbø, Abraham Brouwer, Bart van der Burg
Publikováno v:
Environment International, Vol 143, Iss , Pp 105948- (2020)
In this paper, we investigated the possible presence of endocrine disrupting chemicals (EDCs) based on measuring the total estrogenic and androgenic activity in human milk samples. We used specific bioassays for analysis of the endocrine activity of
Externí odkaz:
https://doaj.org/article/c462c440116b4f10a0d21954119f344f
Autor:
Erika Moro, Johannes P Schimming, José V. Castell, Bas ter Braak, Laia Tolosa, Barbara M.A. van Vugt-Lussenburg, Bob van der Water, Teresa Martínez-Sena, Miguel A. Miranda, Sylvia Escher
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Archives of Toxicology, 95(6), 2109-2121. Springer Science and Business Media LLC
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Archives of Toxicology
instname
Archives of Toxicology, 95(6), 2109-2121. Springer Science and Business Media LLC
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Archives of Toxicology
Phenols are regarded as highly toxic chemicals. Their effects are difficult to study in in vitro systems because of their ambiguous fate (degradation, auto-oxidation and volatility). In the course of in vitro studies of a series of redox-cycling phen
Autor:
Wanda van der Stel, Susanne Hougaard Bennekou, Anna Forsby, Paul Jennings, Johannes Delp, Marcel Leist, Bob van de Water, Ilinca Suciu, Petra Kranaster, Giada Carta, Vesna Munic Kos, Andrea Cediel-Ulloa, Barbara M.A. van Vugt-Lussenburg
Publikováno v:
Archives of Toxicology
Delp, J, Cediel-Ulloa, A, Suciu, I, Kranaster, P, van Vugt-Lussenburg, B M, Munic Kos, V, van der Stel, W, Carta, G, Bennekou, S H, Jennings, P, van de Water, B, Forsby, A & Leist, M 2021, ' Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors ', Archives of Toxicology, vol. 95, no. 2, pp. 591-615 . https://doi.org/10.1007/s00204-020-02970-5
Archives of Toxicology, 95, 591-615. Springer Science and Business Media LLC
Archives of Toxicology, 95(2), 591-615. Springer Verlag
Delp, J, Cediel-Ulloa, A, Suciu, I, Kranaster, P, van Vugt-Lussenburg, B M, Munic Kos, V, van der Stel, W, Carta, G, Bennekou, S H, Jennings, P, van de Water, B, Forsby, A & Leist, M 2021, ' Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors ', Archives of Toxicology, vol. 95, pp. 591–615 . https://doi.org/10.1007/s00204-020-02970-5
Delp, J, Cediel-Ulloa, A, Suciu, I, Kranaster, P, van Vugt-Lussenburg, B M, Munic Kos, V, van der Stel, W, Carta, G, Bennekou, S H, Jennings, P, van de Water, B, Forsby, A & Leist, M 2021, ' Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors ', Archives of Toxicology, vol. 95, no. 2, pp. 591-615 . https://doi.org/10.1007/s00204-020-02970-5
Archives of Toxicology, 95, 591-615. Springer Science and Business Media LLC
Archives of Toxicology, 95(2), 591-615. Springer Verlag
Delp, J, Cediel-Ulloa, A, Suciu, I, Kranaster, P, van Vugt-Lussenburg, B M, Munic Kos, V, van der Stel, W, Carta, G, Bennekou, S H, Jennings, P, van de Water, B, Forsby, A & Leist, M 2021, ' Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors ', Archives of Toxicology, vol. 95, pp. 591–615 . https://doi.org/10.1007/s00204-020-02970-5
Inhibition of complex I of the mitochondrial respiratory chain (cI) by rotenone and methyl-phenylpyridinium (MPP +) leads to the degeneration of dopaminergic neurons in man and rodents. To formally describe this mechanism of toxicity, an adverse outc
Autor:
Harrie Besselink, Barbara M.A. van Vugt-Lussenburg, Bart van der Burg, Abraham Brouwer, Clémence Budin, Hai yen Man
Publikováno v:
Budin, C, Besselink, H, van Vugt-Lussenburg, B M A, Man, H Y, van der Burg, B & Brouwer, A 2021, ' Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DR human CALUX reporter gene assay ', Chemosphere, vol. 263, 128086, pp. 1-9 . https://doi.org/10.1016/j.chemosphere.2020.128086
Chemosphere
Chemosphere, 263:128086, 1-9. Elsevier Limited
Chemosphere
Chemosphere, 263:128086, 1-9. Elsevier Limited
Polychlorinated dioxins and dibenzofurans (PCDD/Fs) are highly toxic contaminants that are strictly regulated and monitored in the environment and food to reduce human exposure. Recently, the increasing occurrence of polybrominated dioxins and dibenz
Autor:
Alejandro Aguayo-Orozco, Liliana Capinha, Nazanin Golbamaki, Enrico Mombelli, Matthias Wehr, Bart van der Burg, Daria Goldmann, Nanette G Vrijenhoek, Thomas Exner, Richard Maclennan, Katharina Brotzmann, Ulf Norinder, Oliver Hatley, Alice Limonciel, Thomas Braunbeck, Sylvia Escher, Barbara Zdrazil, Frédéric Y. Bois, Paul Jennings, Emilio Benfenati, Domenico Gadaleta, Jose Castel, Ciarán Fisher, Sankalp Jain, Anthony Long, Rabea Graepel, Laia Tolosa, Andrew White, Bob van de Water, Barbara M.A. van Vugt-Lussenburg, Paul Walker, Annette Bitsch, Olivier Taboureau, Iain Gardner
Publikováno v:
Toxicology in Vitro, 79:105269, 1-16. Elsevier Limited
Escher, S E, Aguayo-Orozco, A, Benfenati, E, Bitsch, A, Braunbeck, T, Brotzmann, K, Bois, F, van der Burg, B, Castel, J, Exner, T, Gadaleta, D, Gardner, I, Goldmann, D, Hatley, O, Golbamaki, N, Graepel, R, Jennings, P, Limonciel, A, Long, A, Maclennan, R, Mombelli, E, Norinder, U, Jain, S, Capinha, L S, Taboureau, O T, Tolosa, L, Vrijenhoek, N G, van Vugt-Lussenburg, B M A, Walker, P, van de Water, B, Wehr, M, White, A, Zdrazil, B & Fisher, C 2022, ' Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action ', Toxicology in Vitro, vol. 79, 105269, pp. 1-16 . https://doi.org/10.1016/j.tiv.2021.105269
Escher, S E, Aguayo-Orozco, A, Benfenati, E, Bitsch, A, Braunbeck, T, Brotzmann, K, Bois, F, van der Burg, B, Castel, J, Exner, T, Gadaleta, D, Gardner, I, Goldmann, D, Hatley, O, Golbamaki, N, Graepel, R, Jennings, P, Limonciel, A, Long, A, Maclennan, R, Mombelli, E, Norinder, U, Jain, S, Capinha, L S, Taboureau, O T, Tolosa, L, Vrijenhoek, N G, van Vugt-Lussenburg, B M A, Walker, P, van de Water, B, Wehr, M, White, A, Zdrazil, B & Fisher, C 2022, ' Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action ', Toxicology in Vitro, vol. 79, 105269 . https://doi.org/10.1016/j.tiv.2021.105269
Toxicology in Vitro
Toxicology In Vitro, 79
Escher, S E, Aguayo-Orozco, A, Benfenati, E, Bitsch, A, Braunbeck, T, Brotzmann, K, Bois, F, van der Burg, B, Castel, J, Exner, T, Gadaleta, D, Gardner, I, Goldmann, D, Hatley, O, Golbamaki, N, Graepel, R, Jennings, P, Limonciel, A, Long, A, Maclennan, R, Mombelli, E, Norinder, U, Jain, S, Capinha, L S, Taboureau, O T, Tolosa, L, Vrijenhoek, N G, van Vugt-Lussenburg, B M A, Walker, P, van de Water, B, Wehr, M, White, A, Zdrazil, B & Fisher, C 2022, ' Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action ', Toxicology in Vitro, vol. 79, 105269, pp. 1-16 . https://doi.org/10.1016/j.tiv.2021.105269
Escher, S E, Aguayo-Orozco, A, Benfenati, E, Bitsch, A, Braunbeck, T, Brotzmann, K, Bois, F, van der Burg, B, Castel, J, Exner, T, Gadaleta, D, Gardner, I, Goldmann, D, Hatley, O, Golbamaki, N, Graepel, R, Jennings, P, Limonciel, A, Long, A, Maclennan, R, Mombelli, E, Norinder, U, Jain, S, Capinha, L S, Taboureau, O T, Tolosa, L, Vrijenhoek, N G, van Vugt-Lussenburg, B M A, Walker, P, van de Water, B, Wehr, M, White, A, Zdrazil, B & Fisher, C 2022, ' Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action ', Toxicology in Vitro, vol. 79, 105269 . https://doi.org/10.1016/j.tiv.2021.105269
Toxicology in Vitro
Toxicology In Vitro, 79
Read-across approaches often remain inconclusive as they do not provide sufficient evidence on a common mode of action across the category members. This read-across case study on thirteen, structurally similar, branched aliphatic carboxylic acids inv
Autor:
Clémence Budin, Sylvie Puel, Abraham Brouwer, Laura Soler, Barbara M.A. van Vugt-Lussenburg, Hai-Yen Man, Bart van der Burg, Isabelle P. Oswald, Carine Al-Ayoubi
Publikováno v:
Budin, C, Man, H Y, Al-Ayoubi, C, Puel, S, van Vugt-Lussenburg, B M A, Brouwer, A, Oswald, I P, van der Burg, B & Soler, L 2021, ' Versicolorin A enhances the genotoxicity of aflatoxin B1 in human liver cells by inducing the transactivation of the Ah-receptor ', Food and Chemical Toxicology, vol. 153, 112258, pp. 1-9 . https://doi.org/10.1016/j.fct.2021.112258
Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2021, 153, pp.112258. ⟨10.1016/j.fct.2021.112258⟩
Food and Chemical Toxicology, 153:112258, 1-9. Elsevier Limited
Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2021, 153, pp.112258. ⟨10.1016/j.fct.2021.112258⟩
Food and Chemical Toxicology, 153:112258, 1-9. Elsevier Limited
International audience; Aflatoxins are a group of mycotoxins that have major adverse effects on human health. Aflatoxin B1 (AFB1) is the most important aflatoxin and a potent carcinogen once converted into a DNA-reactive form by cytochrome P450 enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5df3e2d0730fbcd85b809778b47af5
https://research.vu.nl/en/publications/907af404-8436-47ae-b913-f845b5282d54
https://research.vu.nl/en/publications/907af404-8436-47ae-b913-f845b5282d54
Autor:
Barbara M.A. van Vugt-Lussenburg, Guilherme M. Grosseli, Abraham Brouwer, Gustavo B. Gregoracci, Flávia Talarico Saia, Alette A.M. Langenhoff, Bas van der Zaan, Pedro Sergio Fadini, Raiane G.M. de Oliveira, Rafaela Tomazini, Antonio Mozetto
Publikováno v:
Water, Air, and Soil Pollution 232 (2021) 3
Water, Air, and Soil Pollution, 232(3):123, 1-13. Springer Netherlands
Tomazini, R, Saia, F T, van der Zaan, B, Grosseli, G M, Fadini, P S, de Oliveira, R G M, Gregoracci, G B, Mozetto, A, van Vugt-Lussenburg, B M A, Brouwer, A & Langenhoff, A A M 2021, ' Biodegradation of Fipronil : Transformation Products, Microbial Characterisation and Toxicity Assessment ', Water, Air, and Soil Pollution, vol. 232, no. 3, 123, pp. 1-13 . https://doi.org/10.1007/s11270-021-05071-w
Water, Air, and Soil Pollution, 232(3)
Water, Air, and Soil Pollution, 232(3):123, 1-13. Springer Netherlands
Tomazini, R, Saia, F T, van der Zaan, B, Grosseli, G M, Fadini, P S, de Oliveira, R G M, Gregoracci, G B, Mozetto, A, van Vugt-Lussenburg, B M A, Brouwer, A & Langenhoff, A A M 2021, ' Biodegradation of Fipronil : Transformation Products, Microbial Characterisation and Toxicity Assessment ', Water, Air, and Soil Pollution, vol. 232, no. 3, 123, pp. 1-13 . https://doi.org/10.1007/s11270-021-05071-w
Water, Air, and Soil Pollution, 232(3)
Fipronil is a highly active, broad spectrum insecticide with increasing and wide use. The degradation of fipronil was studied in Brazilian soil under oxic and anoxic conditions. Under oxic conditions, the half-life of fipronil was 16.9 days, with fip
Autor:
Barbara M.A. van Vugt-Lussenburg, Kees Swart, Abraham Brouwer, Bart van der Burg, Merete Eggesbø, Bérénice Collet, Rick Helmus, Matthijs Naderman, Eva de Rijke
Publikováno v:
Environment International, 143:105948. Elsevier Ltd
Environment International, Vol 143, Iss, Pp 105948-(2020)
Environment International, 143:105948, 1-11. Elsevier Limited
Collet, B, van Vugt-Lussenburg, B M A, Swart, K, Helmus, R, Naderman, M, de Rijke, E, Eggesbø, M, Brouwer, A & van der Burg, B 2020, ' Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort ', Environment International, vol. 143, 105948, pp. 1-11 . https://doi.org/10.1016/j.envint.2020.105948
Environment International
Environment International, Vol 143, Iss, Pp 105948-(2020)
Environment International, 143:105948, 1-11. Elsevier Limited
Collet, B, van Vugt-Lussenburg, B M A, Swart, K, Helmus, R, Naderman, M, de Rijke, E, Eggesbø, M, Brouwer, A & van der Burg, B 2020, ' Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort ', Environment International, vol. 143, 105948, pp. 1-11 . https://doi.org/10.1016/j.envint.2020.105948
Environment International
In this paper, we investigated the possible presence of endocrine disrupting chemicals (EDCs) based on measuring the total estrogenic and androgenic activity in human milk samples. We used specific bioassays for analysis of the endocrine activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab71d00126942396445231b981c23847
https://dare.uva.nl/personal/pure/en/publications/antagonistic-activity-towards-the-androgen-receptor-independent-from-natural-sex-hormones-in-human-milk-samples-from-the-norwegian-humis-cohort(0a470c8b-e1ad-452f-a96a-38733f81afff).html
https://dare.uva.nl/personal/pure/en/publications/antagonistic-activity-towards-the-androgen-receptor-independent-from-natural-sex-hormones-in-human-milk-samples-from-the-norwegian-humis-cohort(0a470c8b-e1ad-452f-a96a-38733f81afff).html
Autor:
Anja Wilmes, Tobias Strassfeld, Harry Vrieling, Manoj Kumar, Balázs Mihalik, Costanza Rovida, Giorgia Pallocca, Nanette G Vrijenhoek, Ciarán Fisher, Bart van der Burg, Thomas Braunbeck, Xenia Dolde, Alice Krebs, Zofia Janstova, Béla Z. Schmidt, Wiebke Albrecht, Jan G. Hengstler, Tim Brecklinghaus, David A. Fluri, J. J. W. A. Boei, Thomas Exner, Marcel Leist, Tanja Waldmann, Jaffar Kisitu, Anna-Katharina Holzer, Manuel Pastor, Joh Dokler, Andrea Paola Cediel Ulloa, Paul Jennings, Barbara M.A. van Vugt-Lussenburg, Bas ter Braak, Bob van de Water, Anna Forsby, Maja Brajnik, Wolfgang Moritz, Catherine M. Verfaillie, Johannes P Schimming, Rebecca von Hellfeld, Alice Limonciel, Francois Busquet, Julianna Kobolák, Ugis Sarkans, Regina Stöber, Jessica Lundqvist, Andras Dinnyes
Publikováno v:
Archives of Toxicology
Archives of Toxicology, 94(7), 2435-2461. Springer Verlag
Archives of Toxicology, 94(7), 2435-2461. SPRINGER HEIDELBERG
Krebs, A, van Vugt-Lussenburg, B M A, Waldmann, T, Albrecht, W, Boei, J, Ter Braak, B, Brajnik, M, Braunbeck, T, Brecklinghaus, T, Busquet, F, Dinnyes, A, Dokler, J, Dolde, X, Exner, T E, Fisher, C, Fluri, D, Forsby, A, Hengstler, J G, Holzer, A-K, Janstova, Z, Jennings, P, Kisitu, J, Kobolak, J, Kumar, M, Limonciel, A, Lundqvist, J, Mihalik, B, Moritz, W, Pallocca, G, Ulloa, A P C, Pastor, M, Rovida, C, Sarkans, U, Schimming, J P, Schmidt, B Z, Stöber, R, Strassfeld, T, van de Water, B, Wilmes, A, van der Burg, B, Verfaillie, C M, von Hellfeld, R, Vrieling, H, Vrijenhoek, N G & Leist, M 2020, ' The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods ', Archives of Toxicology, vol. 94, no. 7, pp. 2435-2461 . https://doi.org/10.1007/s00204-020-02802-6
Archives of Toxicology, 94(7), 2435-2461
Archives of toxicology, 94:2435-2461
Archives of Toxicology, 94(7), 2435-2461. Springer Verlag
Archives of Toxicology, 94(7), 2435-2461. SPRINGER HEIDELBERG
Krebs, A, van Vugt-Lussenburg, B M A, Waldmann, T, Albrecht, W, Boei, J, Ter Braak, B, Brajnik, M, Braunbeck, T, Brecklinghaus, T, Busquet, F, Dinnyes, A, Dokler, J, Dolde, X, Exner, T E, Fisher, C, Fluri, D, Forsby, A, Hengstler, J G, Holzer, A-K, Janstova, Z, Jennings, P, Kisitu, J, Kobolak, J, Kumar, M, Limonciel, A, Lundqvist, J, Mihalik, B, Moritz, W, Pallocca, G, Ulloa, A P C, Pastor, M, Rovida, C, Sarkans, U, Schimming, J P, Schmidt, B Z, Stöber, R, Strassfeld, T, van de Water, B, Wilmes, A, van der Burg, B, Verfaillie, C M, von Hellfeld, R, Vrieling, H, Vrijenhoek, N G & Leist, M 2020, ' The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods ', Archives of Toxicology, vol. 94, no. 7, pp. 2435-2461 . https://doi.org/10.1007/s00204-020-02802-6
Archives of Toxicology, 94(7), 2435-2461
Archives of toxicology, 94:2435-2461
Hazard assessment, based on new approach methods (NAM), requires the use of batteries of assays, where individual tests may be contributed by different laboratories. A unified strategy for such collaborative testing is presented. It details all proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e81d40cbe9c93d9b654557d3afcabe
https://hdl.handle.net/1887/3184413
https://hdl.handle.net/1887/3184413
Autor:
Abraham Brouwer, Daan S. van Es, Frits van der Klis, Matthijs Naderman, Bart van der Burg, Jérôme Le Nôtre, Barbara M.A. van Vugt-Lussenburg
Publikováno v:
Green Chemistry, 22(6), 1873-1883. Royal Society of Chemistry
Green Chemistry, 22(6), 1873-1883
Van Vugt-Lussenburg, B M A, Van Es, D S, Naderman, M, Le Notre, J, Klis, F V D, Brouwer, A & Van Der Burg, B 2020, ' Endocrine activities of phthalate alternatives; Assessing the safety profile of furan dicarboxylic acid esters using a panel of human cell based reporter gene assays ', Green Chemistry, vol. 22, no. 6, pp. 1873-1883 . https://doi.org/10.1039/c9gc04348a
Green Chemistry 22 (2020) 6
Green Chemistry, 22(6), 1873-1883
Van Vugt-Lussenburg, B M A, Van Es, D S, Naderman, M, Le Notre, J, Klis, F V D, Brouwer, A & Van Der Burg, B 2020, ' Endocrine activities of phthalate alternatives; Assessing the safety profile of furan dicarboxylic acid esters using a panel of human cell based reporter gene assays ', Green Chemistry, vol. 22, no. 6, pp. 1873-1883 . https://doi.org/10.1039/c9gc04348a
Green Chemistry 22 (2020) 6
FDCA esters are highly relevant biobased alternatives for currently used benzene dicarboxylic acid esters. Despite all the developments on 2,5-FDCA applications, to the best of our knowledge thus far no toxicological data were available for 2,5-FDCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d540ae3e09739f54ca7639081890acee
https://research.vu.nl/en/publications/622fdf13-5bde-4835-ad1e-341f5f5a0f04
https://research.vu.nl/en/publications/622fdf13-5bde-4835-ad1e-341f5f5a0f04