Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Barbara M. Iwasiow"'
Autor:
Naghmeh Khoshgoo, Robin Visser, Landon Falk, Chelsea A. Day, Dustin Ameis, Barbara M. Iwasiow, Fuqin Zhu, Arzu Öztürk, Sujata Basu, Molly Pind, Agnes Fresnosa, Mike Jackson, Vinaya Kumar Siragam, Gerald Stelmack, Geoffrey G. Hicks, Andrew J. Halayko, Richard Keijzer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a l
Externí odkaz:
https://doaj.org/article/1fa44ab5d33f4684b3412c079afd0d84
Autor:
Chelsea Day, Barbara M. Iwasiow, Fuqin Zhu, Richard Keijzer, Patrice Eastwood, Naghmeh Khoshgoo, Drew Mulhall, Robin Visser
Publikováno v:
Pediatric surgery international. 36(12)
Congenital diaphragmatic hernia (CDH) is a life-threatening disease associated with pulmonary hypoplasia. CDH occurs approximately 1 in every 2000–3000 live births, and the pathophysiology is unknown. MicroRNAs are short, non-coding RNAs that contr
Publikováno v:
Pediatric Research. 79:766-775
We currently do not know how the herbicide nitrofen induces lung hypoplasia and congenital diaphragmatic hernia in rats. Our aim was to compare the differentially expressed transcriptome of nitrofen-induced hypoplastic lungs to control lungs in embry
Autor:
Mary Patrice Eastwood, Thomas H. Mahood, Francesca Russo, Hongmei Wang, Jan Deprest, Richard Keijzer, Barbara M. Iwasiow, Drew Mulhall
Publikováno v:
Prenatal diagnosis. 38(9)
OBJECTIVE Profiling of miR-200b expression and its targets (transforming growth factor [TGF]-β2 and ZEB2) in the surgical rabbit congenital diaphragmatic hernia (DH) model before and after tracheal occlusion (TO). METHODS Thirty-eight timed-pregnant
Autor:
Ramin Kholdebarin, Barbara M. Iwasiow, Thomas H. Mahood, Chelsea Day, Naghmeh Khoshgoo, Fuqin Zhu, Patrícia Pereira-Terra, Richard Keijzer, Jorge Correia-Pinto, Landon Falk, Carly Fraser, Drew Mulhall
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Epub ahead of print
We aimed to evaluate the use of miR-200b as a prenatal transplacental therapy in the nitrofen rat model of abnormal lung development and congenital diaphragmatic hernia (CDH).Background:Pulmonary hypoplasia (PH) and pulmonary
We aimed to evaluate the use of miR-200b as a prenatal transplacental therapy in the nitrofen rat model of abnormal lung development and congenital diaphragmatic hernia (CDH).Background:Pulmonary hypoplasia (PH) and pulmonary
Publikováno v:
Paediatric respiratory reviews. 22
MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In t
Autor:
Dustin Ameis, Molly Pind, Gerald L. Stelmack, Robin Visser, Andrew J. Halayko, Sujata Basu, Michael F. Jackson, Fuqin Zhu, Landon Falk, Agnes Fresnosa, Vinaya Kumar Siragam, Barbara M. Iwasiow, Naghmeh Khoshgoo, Chelsea Day, Richard Keijzer, Arzu Öztürk, Geoffrey G. Hicks
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower numb
Autor:
Meghan Higgins, Barbara M. Iwasiow, Jorge Correia-Pinto, Richard Keijzer, Patrícia Pereira-Terra, Ramin Kholdebarin
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Purpose Congenital diaphragmatic hernia (CDH) is characterized by a developmental defect in the diaphragm, pulmonary hypoplasia and pulmonary hypertension. NPAS3 is a PAS domain transcription factor regulating Drosophila tracheogenesis. NPAS3 null mi
Autor:
Barbara M. Iwasiow, Jorge Correia-Pinto, Jan Deprest, Robbert J. Rottier, Ramin Kholdebarin, Martin Post, Jinxia Wang, Patrícia Pereira-Terra, Richard Keijzer, Philip DeKoninck, Anne Boerema-de Munck, Fuqin Zhu, Naghmeh Khoshgoo, Dick Tibboel
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Annals of Surgery, 262(6), 1130-1140. Lippincott Williams & Wilkins
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Annals of Surgery, 262(6), 1130-1140. Lippincott Williams & Wilkins
"Epub ahead of print 2015 Jan 5"
OBJECTIVE AND BACKGROUND: Our objective was to determine the fetal in vivo microRNA signature in hypoplastic lungs of human fetuses with severe isolated congenital diaphragmatic hernia (CDH) and changes in trache
OBJECTIVE AND BACKGROUND: Our objective was to determine the fetal in vivo microRNA signature in hypoplastic lungs of human fetuses with severe isolated congenital diaphragmatic hernia (CDH) and changes in trache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d68bb3c89971c51b0a536f503b1cc29
Publikováno v:
Early human development. 87(11)
Congenital diaphragmatic hernia remains a clinical challenge for both neonatologists and pediatric surgeons. Advancements in mechanical ventilation strategies and neonatal intensive care have improved survival and transformed treatment of congenital