Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Barbara L. F. Kaplan"'
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1273 (2024)
Over the last several years, there has been increased interest in cannabidiol (CBD) to treat various ailments such as pain, anxiety, insomnia, and inflammation. The potential for CBD as an anti-inflammatory therapy has come, in part, from its demonst
Externí odkaz:
https://doaj.org/article/36cd3edfe27e43148d1ba65546e55192
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1215 (2024)
Experimental autoimmune encephalomyelitis (EAE) is a powerful model to study multiple sclerosis (MS). One of the approaches for EAE is to actively immunize with myelin-derived peptides with immune adjuvants. One of the commonly used immune adjuvants
Externí odkaz:
https://doaj.org/article/5e8cb6c8682c49ad949daf353f27e7c9
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Externí odkaz:
https://doaj.org/article/0c557d01901347c8af289c68153622fd
Publikováno v:
Antibodies, Vol 11, Iss 1, p 4 (2022)
The environmental contaminant 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD) is a ligand for the aryl hydrocarbon receptor (AhR). TCDD is well-characterized to produce immunotoxicity, including suppression of antibody production. Previously we showed
Externí odkaz:
https://doaj.org/article/0db478b26c8b480da00f5ff55c4cbf98
Autor:
Barbara L. F. Kaplan
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 494-495 (2018)
Externí odkaz:
https://doaj.org/article/86bcb2a6db1245cfb8a69a1203fbf7d3
Autor:
James M. Nichols, Barbara L. F. Kaplan
Publikováno v:
Cannabis and Cannabinoid Research. 6:300-314
Introduction: Activation of the peripheral immune system and the infiltration of immune cells into the central nervous system are both key features of the experimental autoimmune encephalomyelitis ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793bb298b5602780184d11389defe499
https://doi.org/10.1089/can.2020.0046
https://doi.org/10.1089/can.2020.0046
Autor:
Brittany N. Szafran, Abdolsamad Borazjani, Hannah L. Scheaffer, J. Allen Crow, Ann Marie McBride, Oluwabori Adekanye, Caitlin B. Wonnacott, Richard Lehner, Barbara L. F. Kaplan, Matthew K. Ross
Publikováno v:
ACS pharmacologytranslational science. 5(10)
Carboxylesterases are members of the serine hydrolase superfamily and metabolize drugs, pesticides, and lipids. Previous research showed that inhibition of carboxylesterase 1 (CES1) in human macrophages altered the immunomodulatory effects of lipid m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec7d3eb4a3d0571f7f8e7905830083a
https://pubmed.ncbi.nlm.nih.gov/36268116
https://pubmed.ncbi.nlm.nih.gov/36268116
Autor:
James M. Nichols, Evangel Kummari, Barbara L. F. Kaplan, Gabriella Yray, Eun-Ju Yang, Jessica Sherman, Christa Gilfeather, Saphala Dhital, Timothy Morgan
Publikováno v:
J Neuroimmune Pharmacol
In this study cannabidiol (CBD) was administered orally to determine its effects and mechanisms in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). We hypothesized that 75mg/kg of oral CBD given for 5 days after i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff3c41de5ddab39a34646d15d2b1cd7
https://doi.org/10.1007/s11481-020-09917-8
https://doi.org/10.1007/s11481-020-09917-8
Autor:
James M. Nichols, Barbara L. F. Kaplan
Publikováno v:
Cannabis and Cannabinoid Research
Introduction: Cannabidiol (CBD) as Epidiolex® (GW Pharmaceuticals) was recently approved by the U.S. Food and Drug Administration (FDA) to treat rare forms of epilepsy in patients 2 years of age and older. Together with the increased societal accept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e6061254a27800c662e99160a2b0be
https://doi.org/10.1089/can.2018.0073
https://doi.org/10.1089/can.2018.0073
Autor:
Amye, McDonald, Ashleigh, Nicaise, Erin Rushing, Sears, Abigail, Bell, Evangel, Kummari, Barbara L F, Kaplan
Publikováno v:
Toxicology and Applied Pharmacology. 454:116259
Part of the mechanism by which 2,3,7.8-tetrachlorodibenzo-p-dioxin (TCDD) suppresses immune function involves induction of regulatory T cells and suppression of effector T cells. The goal of this project was to examine whether TCDD's suppression of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64b0ac755e45f895f3f4361d5981a0b
https://doi.org/10.1016/j.taap.2022.116259
https://doi.org/10.1016/j.taap.2022.116259